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�����״��������� 总被引：1，自引：0，他引：1
??The aim of the paper is to expound that document disseminations in a certain society are an organic whaic consisting of carious kinds. It divides document disseminatians into different types according to the relation be- tween disseminators and disseminated documents, the nature of processes, reiatians and functions of the dissemina- Lions. And then the characteristics, functions and shortcomings of each type of dncumant disseminatiarzs are dis- cussed. 相似文献
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Wang Baixiang Yang Jiakang Fan Lijie Wang Yu Zhang Chenqiu Wang Huiming 《Journal of Zhejiang University. Science. B》2021,22(5):410-420
Hypertension is a prevalent systemic disease in the elderly, who can suffer from several pathological skeletal conditions simultaneously, including osteoporosis. Benidipine(BD), which is widely used to treat hypertension, has been proved to have a beneficial effect on bone metabolism. In order to confirm the osteogenic effects of BD, we investigated its osteogenic function using mouse MC3 T3-E1 preosteoblast cells in vitro. The proliferative ability of MC3 T3-E1 cells was significantly associated with the concentration of BD, as measured by methylthiazolyldiphenyl-tetrazolium bromide(MTT)assay and cell cycle assay. With BD treatment, the osteogenic differentiation and maturation of MC3 T3-E1 cells were increased,as established by the alkaline phosphatase(ALP) activity test, matrix mineralized nodules formation, osteogenic genetic test,and protein expression analyses. Moreover, our data showed that the BMP2/Smad pathway could be the partial mechanism for the promotion of osteogenesis by BD, while BD might suppress the possible function of osteoclasts through the OPG/RANKL/RANK(receptor activator of nuclear factor-κB(NF-κB)) pathway. The hypothesis that BD bears a considerable potential in further research on its dual therapeutic effect on hypertensive patients with poor skeletal conditions was proved within the limitations of the present study. 相似文献
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储嘉康 《宁波大学学报(教育科学版)》1988,(2)
本文讨论了国家经济信息系统县级网络的投资原则、效益分析方法及投资优化的数学模型,并给出了若干分析和计算的实例。 相似文献
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我国西部地区包括广西、云南、贵州、四川、重庆、西藏、甘肃、新疆、陕西、宁夏、内蒙古、青海等省、自治区、直辖市.那里土地辽阔,人口稀少,资源丰富,农业发展潜力很大,但西部地区也有其明显的弱点,即生态环境比较脆弱.因此,开发西部必须处理好经济发展与生态建设之间的关系,这可能需要经过几代人的努力.下面着重谈三个问题. 相似文献
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在总结我国金融情报工作产生背景的基础上，深入分析了国内金融情报兴起和发展的现状，以及理论研究的动向及其最新进展，认为当前我国金融情报服务体系的建设中，存在着观念陈旧、功能作用有局限性、理论研究与学科发展滞后和专业人才短缺等四个方面的问题，并提出了解决上述问题的三点对策建议。 相似文献
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关于图书馆学理论基础及其研究的几点思考 总被引：3，自引：0，他引：3
Less attention was paid to diffrentiating theoretical basis from basic theory in the theoretical study of library science in the past,with the result that a tendency of arbitrary nature,blindness and simplification was shown in the process of the study made for theoretical basis.The paper holds that the basic theory of library science refers to abatracting and generalized entirely and macroscopically the library representation so as to explore its essence,probe into its production and development and lastly,build the system of library science on the basis of summing up the rich library practices.The theoretical basis ,however,starting with the greater and higher object coverage including the library itself,is an abstract recognition of higher level of th essential phenomenon enbodied by the library activities.In many ways,the paper goes deep into and in detail the thoretical basis.ref.14 相似文献
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<正> 信息是构成客观观界的三基元之一。人们认识、加工信息的结果(即知识)常常以文献的形式出现,形成以文献为载体的信息——文献信息。文献信息是人类智慧的结晶,是维系社会精神的精灵,是一种可再生的社会资源。文献信息的生产、发行、存储和开发利用各行业、各部门组成社会文献信息系统——这是一个具有独立意义的、作为社会大系统的有机构件的系统。这一系统是伴随着人类文明的发达而历史地建立和发展起来的。在上古,伴随着文字的创始,文献产生了。最早的文献以天然物质为载体。在国外有泥版、纸莎草,在我国则有甲骨、金石、 相似文献
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