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1.
Dipankar Bhattacharya 《Resonance》2006,11(12):35-44
Newton’s law of universal gravitation laid the physical foundation of celestial mechanics. This article reviews the steps
towards the law of gravitation, and highlights some applications to celestial mechanics found in Newton’sPrincipia.
His research interests cover all types of cosmic explosions and their remnants. 相似文献
2.
Larry Peterson Tom Anderson Dan Blumenthal Dean Casey David Clark Deborah Estrin Joe Evans Mike Reiter Scott Shenker John Wroclawski 洪丹 陈茂科 《中国教育网络》2006,(11):18-20
2006年8月,GEN(I网络创新的全球化环境)项目组公布其项目的设计原则。来自普林斯顿大学、麻省理工大学、华盛顿大学等学校的十二位专家编写了这份报告。该报告阐述了GENI的研究范围、用户的需求、需求的内在压力,以及工程设计的原则。报告指出了GENI的价值主张,广泛的部署、多样化可扩展的网络技术集合、对真实用户流量的支持仍是GENI关注的原则和方向。上期已经介绍第一部分——“分布式需求定义GENI的重心”,本期刊出第二部分——“解决分布式需求的内在冲突”。 相似文献
3.
Neelima Verma Jyoti chakraverty Pankaj Baweja Alka Girotra Leena Chatterjee Manish Chugh 《Indian journal of clinical biochemistry : IJCB》2017,32(1):117-120
Hyperferritinemia (>10,000 ng/ml) is an important hallmark used as an indicator of infection triggered macrophage activation syndrome leading to hemophagocytic lympho histiocytosis (HLH). Measurement of serum ferritin can be used in diagnosis as well as disease monitoring indicator and prognosis related to HLH, cAPS, sepsis, neoplasm and inflammatory conditions. It is a major contributor to manage critically ill patients as predicting and monitoring indicator. It can be used as acute phase response in conditions of MAS, AOSD, cAPS etc. A case study in our hospital showed extremely high ferritin values along with low hemoglobin, elevated LDH and triglycerides with positive MRSA in sputum culture and macrophage proliferation and hemophagocytosis in the bone marrow examination. Patient showed definite inverse relation with steroid therapy and serum ferritin levels. 相似文献
4.
Asma Ahmed Banishree Saha Anand Patwardhan Shwetha Shivprasad Dipankar Nandi 《Resonance》2009,14(5):455-471
How do we remain healthy, for the most parts, in the midst of an environment teeming with opportunistic and infectious microbes, potential carcinogens and allergens? The fact is that our immune system, by and large, does a fine job in protecting us. It is therefore important to understand the organization of the immune network, which is broadly categorized into two groups: innate and adaptive. Cells involved in innate immunity are the first to come into contact with invading microbes, similar to the border security force, and respond rapidly but in a non-specific manner. On the other hand, the cells involved in adaptive immunity are slower to respond but act in a very specific manner. Though the primary response is slow, the secondary response is much faster and demonstrates memory. This article will focus on some important features and key players involved in the adaptive immune response. The first part deals with the humoral immune response mediated mainly by immunoglobulins produced by the B cells. The second part deals with T cells, the Major Histocompatibility Complex (MHC)-encoded molecules, and Recombination Activating Genes (RAG) responsible for generating diverse B-cell receptors (BCR) and T-cell receptors (TCR). With the advent of newer and smarter infectious agents, it is important to understand the working of the immune network as more research in this area may facilitate the development of better protective strategies. 相似文献
5.
Mukta Deobagkar-Lele Chetana Bhaskarla Rajkumar Dhanaraju Manikandan Ponnusamy Dipankar Nandi 《Resonance》2012,17(10):974-995
The 2011 Nobel Prize inMedicine or Physiology was awarded to Jules Hoffmann, Bruce Beutler and Ralph Steinman for their contributions in the area of Innate Immunity. This review introduces the readers to innate immunity and links the studies of the awardees to this area of research. The cells and mechanisms involved in the innate immune response are reviewed with a special emphasis on the discovery of the Toll receptors in Drosophila and the Toll-like receptors in mammals. The importance of the innate response during inflammatory conditions is discussed and examples of genes related to innate immunity that cause disease are also highlighted. Finally, the roles of innate immunity in modulating adaptive immune response, especially with respect to dendritic cells, are discussed. Further studies in this area are likely to enhance our understanding of the immune response and may lead to drugs to ameliorate excessive inflammatory responses. 相似文献
6.
Both (a) in-school factors such as over-focus on academic performance, absence of uniform, and corporal punishment, and (b) out-of school factors such as caring for ailing parents, child labour, etc., hinder participation of orphan and vulnerable children (OVC) in Free Primary Education (FPE) system in Nyanza Province, Kenya. In this context Concern Worldwide Kenya undertook an appreciative capacity building approach and appropriately positioned District Education Office (DEO) of the Ministry of Education and local civil society organisations (CSOs) to address in-school and out-of-school factors, respectively, to ensure quality education for OVC. The outcome of the programme is promising and has demonstrated the need for greater cooperation between CSOs and the government to develop creative strategies in overcoming the causes of marginalisation within the contexts of the growing AIDS pandemic and poverty in Kenya. 相似文献
7.
Y. P. Singh O. P. Sachdeva S. K. Aggarwal K. Chugh Harbans Lal 《Indian journal of clinical biochemistry : IJCB》2008,23(3):290-292
Blood glutathione was estimated in fifty patients of head and neck cancer in the age group of 18–76 years and the results
were compared with a group of normal healthy controls. Mean blood glutathione level was found to be significantly lowered
in patients than the controls. Irrespective of the site, TNM classification, histopathology, and character of lesion, fall
in blood glutathione was nearly same in all the patients. The mean level was significantly increased after radiotherapy when
compared with the levels before radiotherapy. The decreased levels of GSH in-patients with head and neck cancer, observed
in the present study, may be due to its increased utilization by the cells. The results suggest that patients with head and
neck cancer have increased oxidative stress. 相似文献
8.
Harbans Lal Kiran Chugh Varinder Saini Jasbinder Kaur A. S. Saini 《Indian journal of clinical biochemistry : IJCB》1993,8(1):33-35
Glutathione-5-transferase (GST) and glutathione (GSH) levels were estimated in the lungs of 3 and 30 months old rats. GST activity was found to be significantly reduced in the old rats (30 months age) compared to the young rats (3 months age). In old rats, with methionine supplementation GST activity was increased whereas with vitamin C supplementation GSH levels were increased. The data show that the supplementation of methionine as well as of vitamin C have beneficial effect on the scavenging system and protect lungs against the free radical damage during ageing. 相似文献
9.
Naveen Chitkara R. C. Dadoo Sadhna Bansal Kiran Chugh S. K. Aggarwal Harbans Lal 《Indian journal of clinical biochemistry : IJCB》1996,11(2):162-164
Plasma vitamin E levels were estimated in 75 patients each of carcinoma breast and benign breast diseases. Mean plasma vitamin E concentration was found to be significantly reduced in malignancy compared to the controls as well as the non malignant conditions. The decrease in plasma vitamin E in cancer patients was directly related with the TNM stage of cancer. The levels, however, did not vary significantly with respect to histopathology or after 8 days of surgery. 相似文献
10.
Sighting Sapria in the wild is a lifetime experience for a botanist. Because this rare, parasitic flowering plant is one of the lesser known and poorly understood taxa, which is on the brink of extinction. In India, Sapria is only found in the forests of Namdapha National Park in Arunachal Pradesh. In this article, an attempt has been made to document the diversity, distribution, ecology, and conservation need of this valuable plant. 相似文献