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The functions of the eukaryotic cell rely onmembrane-bound compartments called organelles. Each of these possesses distinct membrane composition and unique function. In the 1970’s, during George Palade’s time, it was unclear how these organelles communicate with each other and perform their biological functions. The elegant research work of James E Rothman, Randy W Schekman and Thomas C Südhof identified the molecular machinery required for membrane trafficking, vesicle fusion and cargo delivery. Further, they also showed the importance of these processes for biological function. Their novel findings helped to explain several biological phenomena such as insulin secretion, neuron communication and other cellular activities. In addition, their work provided clues to cures for several neurological, immunological and metabolic disorders. This research work laid the foundation to the field of molecular cell biology and these post-Palade investigators were awarded the Nobel Prize in Physiology or Medicine in 2013. 相似文献
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Audrey Scranton Tamara Afifi Walid Afifi Katlyn Gangi 《Journal of Intercultural Communication Research》2016,45(6):449-469
Undocumented Latin American immigrants are one of the fastest-growing populations in the United States, and they are one of the most vulnerable. Due to constant fear of deportation, these immigrants have to communicatively “pass” for documented in a variety of situations, and they might be likely to use informal network ties (social capital) to do so. Through eight diverse focus group interviews of undocumented immigrants, this study explores how this population passes. Undocumented immigrants used talk, the body, or documents to pass either individually or through network members. Implications for both theory and practice are discussed. 相似文献
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Devon N. Gangi Sofie Boterberg Amy J. Schwichtenberg Erika Solis Gregory S. Young Ana-Maria Iosif Sally Ozonoff 《Child development》2021,92(3):e285-e295
Two independent cohorts (N = 155, N = 126) of infants at high and low risk for autism spectrum disorder (ASD) were followed prospectively between 6 and 36 months of age, when n = 46 were diagnosed with ASD. Gaze to adult faces was coded—during a developmental assessment (Cohort 1) or a play interaction (Cohort 2). Across both cohorts, most children developing ASD showed sharp declines in gaze to faces over time, relative to children without ASD. These findings suggest that declining developmental trajectories may be more common than previously recognized by retrospective methods. Trajectory-based screening methods could potentially identify children in the early stages of symptom onset and allow for early intervention before the full disorder has developed. 相似文献
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A growing body of research has investigated the comments by students on websites that offer evaluations of college faculty. This corpus includes both quantitative and qualitative studies that each use a different scheme for classifying/analysing student comments, which makes the comparison of findings across studies impossible. The present study used a grounded theory method to develop a model for classifying the content of student comments on faculty rating sites that can be applied across studies. The multi‐dimensional nature of the model allows for the representation of the interconnected nature of the topics addressed by students in their comments and allows for comments to be categorised with varying degrees of specificity. Future research is needed to test the validity of the model for addressing various research questions. 相似文献
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Norah E. Dunbar Katlyn Gangi Samantha Coveleski Aubrie Adams Quinten Bernhold Howard Giles 《Communication Studies》2016,67(2):129-146
While deception is generally viewed as an undesirable and unethical action, people evaluate some lies as more detrimental than others. This study examined factors influencing deception assessments, including the seriousness of the lie and whom it benefits. The effect of an intergroup versus an interpersonal context for the lie was examined. Utilizing 24 vignettes varying in terms of these conditions, 259 participants evaluated a lie’s appropriateness, deceptiveness, and complexity. Altruistic and white lies were viewed as less deceptive and more acceptable than self-serving and more consequential lies. Lies evaluated as least acceptable were interpersonal, serious, and self-serving compared to altruistic lies and those embedded in an intergroup context. Intergroup and interpersonal deceptions are recognized as distinct forms of lying and are evaluated differently. 相似文献
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