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We describe how a team approach that we developed as a mentoring strategy can be used to recruit, advance, and guide students to be more interested in the interdisciplinary field of mathematical biology, and lead to success in undergraduate research in this field. Students are introduced to research in their first semester via lab rotations. Their participation in the research of four faculty members-two from biology and two from mathematics-gives them a first-hand overview of research in quantitative biology and also some initial experience in research itself. However, one of the primary goals of the lab rotation experience is that of developing teams of students and faculty that combine mathematics and statistics with biology and the life sciences, teams that subsequently mentor undergraduate research in genuine interdisciplinary environments. Thus, the team concept serves not only as a means of establishing interdisciplinary research, but also as a means of incorporating new students into existing research efforts that will then track those students into meaningful research of their own. We report how the team concept is used to support undergraduate research in mathematical biology and what types of team-building strategies have worked for us. 相似文献
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Katie J. Thralls Suneeta Godbole Todd M. Manini Eileen Johnson Loki Natarajan Jacqueline Kerr 《Journal of sports sciences》2013,31(20):2309-2317
ABSTRACTThis study compared five different methods for analyzing accelerometer-measured physical activity (PA) in older adults and assessed the relationship between changes in PA and changes in physical function and depressive symptoms for each method. Older adult females (N = 144, Mage = 83.3 ± 6.4yrs) wore hip accelerometers for six days and completed measures of physical function and depressive symptoms at baseline and six months. Accelerometry data were processed by five methods to estimate PA: 1041 vertical axis cut-point, 15-second vector magnitude (VM) cut-point, 1-second VM algorithm (Activity Index (AI)), machine learned walking algorithm, and individualized cut-point derived from a 400-meter walk. Generalized estimating equations compared PA minutes across methods and showed significant differences between some methods but not others; methods estimated 6-month changes in PA ranging from 4 minutes to over 20 minutes. Linear mixed models for each method tested associations between changes in PA and health. All methods, except the individualized cut-point, had a significant relationship between change in PA and improved physical function and depressive symptoms. This study is among the first to compare accelerometry processing methods and their relationship to health. It is important to recognize the differences in PA estimates and relationship to health outcomes based on data processing method.Abbreviation: Machine Learning (ML); Short Physical Performance Battery (SPPB); Center of Epidemiologic Studies Depression Scale (CES-D); Physical Activity (PA); Activity Index (AI); Activities of Daily Living (ADL) 相似文献
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Arun Kumar B. S. Dhillon D. N. Rao Geetha Menon Hari Shankar L. K. Dhaliwal Maiti Leema Nomita Chandhiok Neeta Kumar Rohini Sehgal Suneeta Mittal Sumitu Sahdev Kandpal Shobha V. L. Jindal 《Indian journal of clinical biochemistry : IJCB》2012,27(4):405-409
Malondialdehyde (MDA) is widely used as oxidative stress biomarker in biomedical research. Plasma is stored in deep freezers generally till analysis. Effect of such storage on MDA values, which may be variable and prolong, was incidentally observed in the ongoing study which is to estimate oxidative stress with oral iron. Plasma from blood samples of pregnant women (20–30 years age) in third trimester of singleton pregnancy (n = 139), consuming oral iron tablets was stored at −20 °C with intention of MDA estimation, as soon as possible. However logistic problems led this storage for prolonged and variable period (1–708 days). When values of MDA estimated using “Ohkawa” 79 method and readings were plotted against time to check the temporal effect, it showed a hyperbolic curve. Standard deviation (SD) was lowest when samples were tested within 3 weeks time. The samples analyzed within 3 weeks had mean ± SD value of 31.59 ± 26.11 μmol/L, while 123.7 ± 93.97 and 366.5 ± 189.8 μmol/L for samples stored for 1–3 and 4 months to 1 year respectively. Mean ± SD were 539.9 ± 196.8 in the samples store for more than a year. Rate of change in values was also lowest (0.0433 μmol/L/day) in the samples tested within first 3 weeks, which rose to 1.2 μmol/L/day during 3 month’s storage. This rate peaked at storage of 120 days (1.87 μmol/L/day) and fell to 0.502 μmol/L/day in the second year of storage. It is concluded that at −20 °C, only 3 weeks of storage time should be considered valid for fairly acceptable stability in MDA values. 相似文献
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Rohini Godbole 《Resonance》2011,16(11):1019-1028
In this article it is pointed out how the different layers of substructure of matter were revealed to us by experiments which
were essentially very similar to the famous α-particle scattering experiment performed by Rutherford. This experiment, which
revealed the nuclear structure of an atom, paved the way towards our current understanding of the fundamental constituents
of matter and shaped the course of physics for the 20th century. 相似文献
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Suneeta Kercood Sydney S. Zentall Megan Vinh Kinsey Tom-Wright 《Contemporary educational psychology》2012
The purpose of this theoretically-based study was to examine the effects of yellow-highlighting ‘relevant’ words and units within math word problems. Initial differences were documented between 10 girls at-risk for ADHD and 10 comparisons on the performance of group and individual assessments of math computations and word problems, as had previously been reported for boys. To address these deficits (faster speed and lower accuracy) for the at-risk group, these fourth-grade girls were randomly assigned word problems under two experimental conditions (highlight vs. nohighlight) within a counterbalanced condition- and form-order design. Intervention gains were (a) slower rate of performance, (b) decreased off-task behavior, and (c) improved problem solving performance, differentially for girls at-risk for ADHD when their materials were first presented with highlighting – the effects of which carried over to a non-highlight condition. The theoretical, practical, and future research implications of this study are addressed. 相似文献
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