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1.
Ling Xia Ying-lan Gong Xiu-wei Zhu Yu Zhang Qi Sun Heng-gui Zhang 《Journal of Zhejiang University. Science. B》2010,11(6):402-416
The aim of this study is to build two mathematical models of canine ionic currents specific to right atria and left atria.The canine left atria mathematical model was firstly modified from the Ramirez-Nattel-Courtemanche(RNC) model using the recently available experimental data of ionic currents and was further developed based on our own experimental data.A model of right atria was then built by considering the differences between right atria and left atria.The two developed models well reproduced the exper... 相似文献
2.
心钠素和醛固酮是体内重要的体液调节激素,运动会引起血浆心钠素(ANP)、醛固酮(ALDO)的增高,血浆心钠素(ANP)随运动强度的增加而增加,系统合理的运动训练能提高血浆心钠素水平,力竭运动血浆ANP含量过度增高,增加潜在的心肌受损的可能性。运动中血浆醛固酮(ALDO)浓度与运动强度和脱水程度相关,血浆心钠素(ANP)与机体脱水程度关系不大。运动中检测心钠素、醛固酮浓度的变化对合理制定运动强度、科学指导运动训练具有重要意义。 相似文献
3.
目的探讨血脂对老年慢性心房颤动(chronic atrial fibrillation,CAF)患者发生缺血性中风的影响.方法对资料完整的182例老年(＞60岁)CAF患者进行前瞻性研究,分析血脂与缺血性中风的关系.结果老年CAF患者血清胆固醇和甘油三酯增高、高密度脂蛋白降低与缺血性中风有明显关系(P＜0.05),其中胆固醇增高与缺血性中风关系最显著(P＜0.001).结论血脂异常是老年CAF患者发生缺血性中风的重要危险因素. 相似文献
4.
Kai Jiang Chao Huang Shu-ming Ye Hang Chen 《Journal of Zhejiang University. Science. B》2012,13(9):751-756
Atrial fibrillation (AF) has been considered as a growing epidemiological problem in the world, with a substantial impact on morbidity and mortality. Ambulatory electrocardiography (e.g., Holter) monitoring is commonly used for AF diagnosis and therapy and the automated detection of AF is of great significance due to the vast amount of information provided. This study presents a combined method to achieve high accuracy in AF detection. Firstly, we detected the suspected transitions between AF and sinus rhythm using the delta RR interval distribution difference curve, which were then classified by a combination analysis of P wave and RR interval. The MIT-BIH AF database was used for algorithm validation and a high sensitivity and a high specificity (98.2% and 97.5%, respectively) were achieved. Further, we developed a dataset of 24-h paroxysmal AF Holter recordings (n=45) to evaluate the performance in clinical practice, which yielded satisfactory accuracy (sensitivity=96.3%, specificity=96.8%). 相似文献
5.
不同训练水平赛艇运动员多级负荷中血浆心钠素的变化 总被引：4，自引：0，他引：4
本文研究了不同训练水平男子赛艇运动员与健康大学生在进行不同强度负荷后,血浆心钠素与心血管功能的变化,探讨了系统赛艇训练对心脏内分泌及其功能的影响。结果提示系统赛艇训练不影响安静时的血浆心钠素水平,但可提高运动中心钠素对负荷明显反应的强度阈,运动中检测血浆ANP水平的变化,可以用来评价赛艇运动员的训练水平和心脏储备能力。 相似文献
6.
INTRODUCTIONMostparoxysmalatrialfibrillationisactivatedbyatrialectopiesoriginatinginthepulmonaryveins.Severalresearchesdemonstratedthatal most 50 %offocalatrialfibrillationoriginatesintheleftsuperiorpulmonaryveinandabout3 0 %intherightsuperiorpulmonaryvei… 相似文献
7.
Jiang CY Wang JA He H Sun Y Zhou BQ 《Journal of Zhejiang University. Science. B》2005,6(12):1153-1156
INTRODUCTION Pulmonary veins(PV)may play an importantrole in both the initiation and maintenance of parox-ysmal atrial fibrillation(AF)(Fynn and Kalman,2004).Curative treatment of patients with paroxys-mal AF is possible by radiofrequency ablation,mak-ing segmental or linear lesions around the ostia ofPVs using a3-dimentional mapping system(Carto)(Pappone et al.,2000;2001;Oral et al.,2003).Multi-slice spiral computed tomography(MSCT)could generate a3-dimentional image of left atrium… 相似文献
8.
Shu Zhang 《Journal of Zhejiang University. Science. B》2012,13(8):609-615
Atrial fibrillation (AF) increases the risk of stroke. New anticoagulation agents have recently provided alternative and promising approaches. This paper reviews the current state of anticoagulation therapy in AF patients, focusing on various clinical scenarios and on comparisons, where possible, between western and eastern populations. 相似文献
9.
Hui Cheng Yin-yin Dai Ru-hong Jiang Qiang Liu Ya-xun Sun Jian-wei Lin Zu-wen Zhang Shi-quan Chen Jun Zhu Xia Sheng Chen-yang Jiang 《Journal of Zhejiang University. Science. B》2014,15(10):915-922
Objective
To evaluate the incidence and clinical outcome of adenosine triphosphate (ATP) plus isoproterenol (ISP)-induced non-pulmonary vein (PV) foci before and after circumferential PV isolation (CPVI) during index ablation in patients with paroxysmal atrial fibrillation (PAF).Methods
In 80 consecutive patients undergoing catheter ablation for drug-refractory, symptomatic PAF at our hospital from April 2010 to January 2011, atrial fibrillation (AF) was provoked with ATP (20 mg) and ISP (20 μg/min) administration before and after CPVI. The spontaneous initiation of AF was mapped and recorded.Results
Before ablation, AF mostly originating from PVs (PV vs. non-PV, 36/70 vs. 3/70; P<0.01) was induced in 39 patients with sinus rhythm. CPVI significantly suppressed AF inducibility; however, more non-PV foci were provoked (post-CPVI vs. pre-CPVI, 13/76 vs. 3/70; P=0.016). Patients with pre- and post-CPVI induced AF (n=49) were divided according to non-PV foci being induced (group N, n=17) or not (group P, n=32). After mean (19.2±8.2) months follow-up, 88.2% (15/17) and 65.6% (21/32) of patients in groups N and P, respectively, were free from AF recurrence (P=0.088).Conclusions
ATP+ISP administration effectively provokes non-PV foci, especially after CPVI in PAF patients. Although in this study difference did not achieve statistical significance, supplementary ablation targeting non-PV foci might benefit clinical outcome. 相似文献10.