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目的:临床观察中药加味柴芍六君颗粒治疗腹泻型肠易激综合征(irritable bowel syndrome-diarrhea predomina nt,IBS-D)的临床疗效。方法:将80例IBS-D患者随机分为加味柴芍六君颗粒中药组和培菲康西药组,分别给予加味柴芍六君颗粒及口服培菲康治疗。疗程均为4周,疗程结束后随访3个月,观察疗效。结果:(1)治疗2、4周后、治疗结束后第1个月及第3个月随访时,结果两组的证候总积分改善明显优于治疗前,差异有统计学意义(p0.05);(2)治疗4周后,中药组总有效率为81.1%,西药组为70.4%,2组总体疗效差异无统计学意义(p=0.194);在单项症状方面排便次数和大便性状等改善情况中药组要优于西药,差异具有统计学意义(p0.05);(3)在第1、第3个月随访中药组证候积分改善优于西药组,差异具有统计学意义(p0.05)。结论:临床应用加味柴芍六君颗粒治疗IBS-D具有较好的临床疗效。 相似文献
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目的：评价粪便菌群检测在治疗小儿腹泻中的临床意义.方法：通过收集宜春新建医院儿科自2013年6月至2014年1月住院治疗且好转或痊愈出院的腹泻患儿103例,随机分为对照组64例和干预组39例,对照组采用传统治疗方案进行治疗,干预组在传统治疗方案基础上根据粪便菌群检测结果补充相应的微生态制剂,分别对两组对象的住院时间及住院费用进行比较分析.结果：对照组和干预组的平均住院时间分别为5.9 ±2.1d和4.4±1.9d,平均住院费用分别为1661.03±533.17元和1171.5±555.27元,差异均有统计学意义（P＜0.05）.结论：根据粪便菌群检测结果制定小儿腹泻治疗方案进行治疗,可以缩短患儿治疗时间,降低患者治疗费用. 相似文献
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Brijesh S Daswani PG Tetali P Rojatkar SR Antia NH Birdi TJ 《Journal of Zhejiang University. Science. B》2006,7(8):665-674
While data are available on the effect of medicinal plants on intestinal motility and their antibacterial action, there is a paucity of information on their mode of action on various aspects of diarrheal pathogenicity, namely colonization to intestinal epithelial cells and production/action of enterotoxins. Crude decoction of dried leaves of Pongamia pinnata was evaluated for its antimicrobial （antibacterial, antigiardial and antirotaviral） effect; and its effect on production and action of enterotoxins （cholera toxin, CT; Escherichia coli labile toxin, LT; and E. coli stable toxin, ST）; and adherence of enteropathogenic E. coli and invasion of enteroinvasive E. coli and Shigellaflexneri to epithelial cells. The decoction had no antibacterial, antigiardial and antirotaviral activity, but reduced production of CT and bacterial invasion to epithelial cells. The observed results indicated that the crude decoction ofP. pinnata has selective antidiarrheal action with efficacy against cholera and enteroinvasive bacterial strains causing bloody diarrheal episodes. 相似文献
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