The purpose of this study was to investigate the effects of interval aerobic training combined with strength exercise in the same training session on body composition, and glycaemic and lipid profile in obese rats. Sixteen lean Zucker rats and sixteen obese Zucker rats were randomly divided into exercise and sedentary subgroups (4 groups, n = 8). Exercise consisted of interval aerobic training combined with strength exercise in the same training session. The animals trained 60 min/day, 5 days/week for 8 weeks. Body composition, lipid and glycaemic profiles and inflammatory markers were assessed.
Results showed that fat mass was reduced in both lean and obese rats following the exercise training (effect size (95% confidence interval (CI)) = 1.8 (0.5–3.0)). Plasma low-density lipoprotein–cholesterol and fasting glucose were lower in the exercise compared to the sedentary groups (d = 2.0 (0.7–3.2) and 1.8 (0.5–3.0), respectively). Plasma insulin was reduced in exercise compared to sedentary groups (d = 2.1 (0.8–3.4)). Some exercise × phenotype interactions showed that the highest decreases in insulin, homeostatic model assessment-insulin resistance, fasting and postprandial glucose were observed in the obese + exercise group (all, P < 0.01). The findings of this study suggest that interval aerobic training combined with strength exercise would improve body composition, and lipid and glycaemic profiles, especially in obese rats. 相似文献
INTRODUCTION It is well-known from the genetic code structure that there exists a connection between codons and physical and chemical amino acid properties (Lewin, 1983). Codon properties in turn are defined by physical properties of the nucleotides from which they are compounded (Ratner, 1985; 2000). The most important properties of nucleotides as complex three-dimensional molecules are their dipole moment, heat of formation and energy of the most stable con- formation (Schneider and Be… 相似文献
Blood zinc protoporphyrin (ZPP), serum total protein (TP), and total cholesterol (TC) levels in automobile workshop workers
in relation to lead toxicity were analysed. In the present study, automobile workshop workers (healthy male workers at an
age between 28 and 35 from four major automobile workshops in Kottayam, Kerala State, India) and the control (male healthy
adults at an age between 28 and 35 residing at Aymanam, a distant village at Kottayam District, Kerala having reduced or no
chance of lead exposure) displayed significant difference in blood lead (BPb) and blood ZZP (BZPP) level. The mean value of
BPb in automobile workshop workers was 15.76±0.33 μg/dl, while in the control it was 8.20±0.15 μg/dl. In automobile workshop
workers, the mean value of BZPP was 34.2±0.62 μg/dl. The control group exhibited a mean of 11.5±0.22 μg/dl. Automobile workshop
workers exhibited significant increase in BZPP was corresponding to the increase in BPb level. The total protein levels estimated
in automobile workshop workers showed significant decrease compared to control individuals, but was within the reference range
of healthy individuals. The mean value of TP level in automobile workshop workers and control was 6.9±0.13 g/dl and 7.71±0.18
g/dl, respectively. There was no significant difference in blood haemoglobin (BHb) level among the automobile workshop workers
and control. The serum TC level in automobile workshop workers showed significant decrease compared to the control individuals,
but was with in the reference range of healthy individuals. The mean level of serum TC in automobile workshop workers was
162.00±3.44 mg/dl and the same in control was 172.86±4.32 mg/dl. The present study affirms occupational lead toxicity in automobile
workshop workers and its effect on serum protein and cholesterol levels. 相似文献
Prostate Specific Antigen (PSA) has emerged as the most applicable and important tumor marker for carcinoma prostate. In the
present study PSA was determined in serum of healthy subjects, patients of benign prostate hypertrophy (BPH) and Carcinoma
Prostate (Ca−P) to evaluate its diagnostic efficiency in day to day management of prostate cancer patients and in differentiating
patients of early prostate cancer from those with BPH. Receiver operating characteristic curve (ROC) revealed 2 ng/ml and
10 ng/ml cut off serum PSA level for BPH and untreated carcinoma prostate patients (Ca−P). An extremely significant increase
(P<0.0001) was observed in mean PSA concentration in BPH patients and adenocarcinoma prostate patients when compared to healthy
males. Clinical relevance of PSA was highlighted by a case study of cancer patient prior to any therapy till death. 相似文献