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对8例过敏性紫癫病人患者进行症状和全身综合评估,加强病情观察对症护理,防止并发症的发生.结果8例患者中,1例复发,1例出现肾脏病变转院治疗,其余患者获得满意疗效. 相似文献
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柴茂山 《雁北师范学院学报》2011,27(4)
目的探讨调血保肾胶囊预防小儿过敏性紫癜发生发展过程中的肾脏损害,从而降低小儿过敏性紫癜性肾炎的发生率的临床价值。方法设健康组、观察组、对照组,对门诊和住院患儿324例进行临床对比观察,并通过检测尿β2-MG、AIb、TRF、IgG、RBP5种微量蛋白,探讨其预防作用。结果治疗前观察组与对照组尿β2-MG、AIb、TRF、IgG4种微量蛋白均高于健康组（P〈0．01）;而治疗后观察组尿4种微量蛋白与治疗前比较明显降低（尸〈0．05）,对照组与治疗前比较无差异（P〉0．05）;治疗后尿4种微量蛋白观察组与对照组比较亦有差异（P〈0．05）。结论调血保肾胶囊具有预防小儿过敏性紫癜发生发展过程中的肾脏损害、降低小儿过敏性紫癜肾炎发生率的作用,通过尿β2-MG,AIb,TRF,IgG,RBP5种微量蛋白的检测,能够早期发现小儿过敏性紫癜肾脏损害,及时采取预防治疗手段进行有效的治疗。 相似文献
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目的：探讨影响儿童过敏性紫癜（Henoch-Schonlein Purpura,HSP）复发的相关因素,以及采取的预防措施。方法：选取2012年01月至2013年12月在某市级儿童医院住院确诊为HSP,初发病例的患儿作为研究对象,进行回顾性分析。共收集364例患儿,其中失访16例,选择符合诊断标准的患儿348例为研究对象。结果：复发组年龄≥7岁构成比、感染发生率、食物过敏发生率、肾脏受累发生率明显高于未复发组,差异显著（P〈0.05）;复发组男女比例为1.77∶1,未复发组男女比例为1.05∶1,两组男女构成比差异具有统计学意义（P〈0.05）;两组在地区（生活农村、城镇）、发病季节、关节症状、消化道症状、皮疹发生率差异无统计学意义（P〉0.05）。结论：对有上述异常指标患儿应加强随访观察,积极寻找、消除诱因,避免疾病复发与恶化。 相似文献
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Meltem Kilercik Abdurrahman Coskun Mustafa Serteser Deniz Inan Ibrahim Unsal 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2014,24(1):138-145
Background:
The ultra-large von Willebrand factor (vWF) multimers are very active and must be degraded by ADAMTS13 for optimal activity. A severe functional deficiency of ADAMTS13 has been associated with thrombotic thrombocytopenic purpura. The correct interpretation of patient vWF and ADAMTS13 plasma levels requires an understanding of the biological variation associated with these analytes. In the present paper, we aimed to determine the biological variation of ADAMTS13 and vWF in human adults.Materials and methods:
Blood samples were collected weekly from 19 healthy subjects for 5 consecutive weeks. vWF activity and antigenicity were determined using aggregometric and immunoturbidimetric methods. ADAMTS13 antigenicity and activity were determined by ELISA.Results:
The within-subject biological variations for vWF activity and antigenicity were 8.06% and 14.37%, respectively, while the between-subject biological variations were 18.5% and 22.59%, respectively. The index of individuality for vWF activity was 0.44, while vWF antigenicity was 0.64. Similarly, ADAMTS13 activity and antigenicity within-subject biological variations were 12.73% and 9.75%, respectively, while between-subject biological variations were 9.63% and 6.28%, respectively. The ADAMTS13 indexes of individuality were 1.32 and 1.55, respectively.Conclusion:
We report high biological variation and individuality in vWF antigenicity and activity levels. However, ADAMTS13 antigenicity and activity displayed high biological variation, but low individuality. Thus, population-based reference intervals may be useful for monitoring ADAMTS13 antigenicity and activity, but not for vWF, which displays high individuality. These findings should be considered when determining the reference interval and other clinical variables associated with ADAMTS13 and vWF levels. 相似文献5.
吴家钏 《泰州职业技术学院学报》2002,2(3):50-51
应用国产环孢素联合治疗难治性特发性血小板紫癜(ITP)20例。总有效率85％。该方案治疗难治性ITP疗效好，不良反应轻，安全可靠，值得推广。 相似文献
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