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INTRODUCTION Conventional coronary artery bypass graftin(CCABG) with cardiopulmonary bypass (CPB) habeen accepted as an effective and safe treatment fomulti-vessel coronary heat disease. CPB may stilcontribute to the operation field because of threlatively easier technical requirement; but it alscauses a serious systematic inflammatory reactiowhich will lead to dysfunction of important organand higher cost for the patients. Off-pump coronarartery bypass grafting (OPCABG) has r… 相似文献
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ZHANG Yan-xing LIU Jian-ren JIANG biao LIU Hui-qin DING Mei-ping SONG Shui-jiang ZHANG Bao-rong ZHANG Hong XU Bin CHEN Huai-hong WANG Zhong-jin HUANG Jian-zheng 《Journal of Zhejiang University. Science. B》2007,(10)
Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmanry resuscitation often accompanied by action myoclonus and cerebellar ataxia. It is seen in patients who have un-dergone a cardiorespiratory arrest, regained consciousness afterwards, and then developed myoclonus days or weeks after the event. Worldwide, 122 cases have been reported in the literature so far, including 1 case of Chinese. Here we report 2 Chinese LAS patients with detailed neuroimagings. Cranial single photon emission computed tomography (SPECT) of patient 1, a 52-year-old woman, showed a mild hypoperfusion in her left temporal lobe, whereas patient 2, a 54-year-old woman, manifested a mild bilateral decrease of glucose metabolism in the frontal lobes and a mild to moderate decrease of the N-acetyl aspartate (NAA) peak in the bilateral hippocampi by cranial [18F]-fluorodeoxyglucose positron emission tomographic (PET) scan and cranial magnetic resonance spectroscopy (MRS), respectively. We also review the literature on the neuroimaging, pathogenesis, and treatment of LAS. 相似文献
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目的：探讨中药复方枳菊解郁汤对抑郁模型小鼠空间学习记忆能力的影响及其机制。方法：采用多种因素慢性轻度不可预见性应激方式建立抑郁模型小鼠,分别给予小鼠低、中、高剂量枳菊解郁汤处理。采用Morris水迷宫实验,检测小鼠的空间学习记忆能力的变化;通过免疫组织化学方法检测脑内基质细胞衍生因子(SDF-1)的表达。结果：与对照组相比,模型组小鼠的空间学习记忆能力明显下降(P<0.01),SDF-1在海马CA1,CA3,DG及前脑皮层的表达明显降低(P<0.05);与模型组相比,枳菊解郁汤中剂量组小鼠的空间学习记忆能力明显增高(P<0.05),SDF-1在海马CA1,CA3,DG及前脑皮层的表达明显增加(P<0.05)。结论：枳菊解郁汤的抗抑郁作用可能与SDF-1的表达上调有关。 相似文献
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慢性皮肤溃疡是一种中医外科疑难病,病因复杂,现代医学尚缺乏疗效确切的治疗手段。中医药对该病有许多独特疗法,文章主要从中药膏外敷、中药熏洗与湿敷、按摩、针灸、情志饮食等各方面护理特色进行归纳、阐述,为本病的临床护理提供参考。 相似文献
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赵望秦 《陕西师范大学学报(哲学社会科学版)》2004,33(6):67-70
赵嘏《读史编年诗》虽于元明之际已佚 ,但有敦煌残卷遗世。考其内容 ,是一部在特定文化背景和创作风气影响下产生的以七言律诗为形式的训蒙作品 ,写法新颖 ,独具特色。由于不切合儿童的学习特性 ,又成为蒙学史上的一部败笔之作 相似文献
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Venkateshwari A Sri Manjari K Krishnaveni D Nallari P Vidyasagar A Jyothy A 《Indian journal of clinical biochemistry : IJCB》2011,26(2):136-139
Pancreatic fibrosis is a key pathological feature in the etiology of chronic pancreatitis that leads to obliteration of exocrine
and endocrine pancreatic tissues and its replacement by fibrous tissue resulting in clinical manifestations. Matrix metalloproteinase
9 is a member of the MMP family that is also known as gelatinase B, degrades type IV collagen of extracellular matrix and
basal membrane. The present study is aimed at evaluating the clinical significance of plasma concentration of MMP-9 in chronic
pancreatitis. The samples were obtained from 112 chronic pancreatitis patients and an equal number of age and sex matched
healthy controls. MMP-9 levels were quantitatively measured by ELISA assay. Statistical analysis was applied to test the significance
of results. The present study revealed a significant increase of plasma MMP 9 levels in chronic pancreatitis patients compared
to control subjects. Elevated levels were also observed in all the patient groups compared to control subjects with regard
to sex, age, addictions etc. MMP-9 degrades the type IV collagens in normal basement membrane, which in turn activates the
pancreatic stellate cells which promote the development of pancreatitic fibrosis. Thus, elevated plasma levels of MMP-9 may
act as a susceptibility factor for the development of chronic pancreatitis. 相似文献
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Madhusudhana Rao A Anand U Anand CV 《Indian journal of clinical biochemistry : IJCB》2011,26(1):28-31
Numerous lines of evidence implicate a role of myeloperoxidase (MPO) in the pathogenesis of cardiovascular disease (CVD).
It is a well accepted fact that patients with chronic kidney disease (CKD) are at an increased risk for CVD. MPO is a pro-oxidant
enzyme which could be involved in the increased susceptibility of these patients to CVD. Hence, the levels of plasma MPO was
determined in healthy controls as well as in patients with CKD [stratified with the level of their kidney failure as CKD stages
II–V (end stage renal disease)]. Plasma MPO was assayed by a spectrophotometric method. Serum urea and creatinine were estimated
on a clinical chemistry analyzer using standard laboratory procedures. The mean plasma MPO levels were significantly lower
with advancing stages of renal failure (P < 0.001). There was a positive correlation between MPO and GFR (r = +0.89, P < 0.001) and a negative correlation with urea (r = −0.85, P < 0.001) and creatinine (r = −0.82, P < 0.001). While an inverse association was observed between plasma MPO and urea in CKD patients, such an association was
not observed in control subjects (P = 0.43). In conclusion, the decline in plasma MPO levels may be due to the inhibitory effect of uraemic toxins on the enzyme. 相似文献
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目的：观察综合干预对老年慢性便秘患者的治疗效果,探讨老年慢性便秘的综合干预措施。方法：将门诊92例老年慢性便秘患者随机分为对照组45例和观察组47例。对照组采取常规药物治疗,观察组在对照组治疗措施基础上,实施综合干预。为期6个月。结果：观察组患者治疗显效率、总有效率均明显高于对照组（P〈0.05或P〈0.01）;治疗前两组患者老年慢性便秘保健能力均明显高于对照组（P〈0.01）;治疗后第1周,观察组排便困难程度、大便性状评分均明显低于对照组（P〈0.01）,排便次数明显多于对照组（P〈0.01）。结论：综合干预治疗老年慢性便秘疗效显著,值得推广应用。 相似文献
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BackgroundStochastic resonance stimulation (SRS) transmits subsensory electrical Gaussian white noise into the body to enhance sensorimotor function. This therapy has improved static single leg balance in subjects with functional ankle instability. However, the effect of this stimulation on dynamic single leg balance is not known. Improvements in dynamic single leg balance with SRS may have implications for enhancing functional rehabilitation for ankle instability. Thus, the purpose of this study was to determine the effects of SRS on dynamic single leg balance in subjects with functional ankle instability.MethodsThis study was an experimental research design and data were collected in a sports medicine research laboratory. Twelve subjects with functional ankle instability (69 ± 15 kg; 173 ± 10 cm; 21 ± 2 years) reported a history of ankle sprains and instability at the ankle with physical activity. A single leg jump-landing test was used to assess dynamic balance. Subjects were required to jump between 50% and 55% of the maximal vertical jump height, land on a single leg atop a force plate, and stabilize as quickly as possible. Jump-landing tests were performed with and without SRS. Three trials were performed for each treatment condition (SRS and control). A randomized block design was used to determine test order. Anterior/posterior and medial/lateral time-to-stabilization were computed to assess dynamic balance. Lesser time indicated better stability. One-tailed paired samples t tests were used for analysis (α ≤ 0.05).ResultsSRS improved anterior/posterior time-to-stabilization (stochastic resonance = 1.32 ± 0.31 s, control = 1.74 ± 0.80 s, p = 0.03), but did not enhance medial/lateral time-to-stabilization (stochastic resonance = 1.95 ± 0.40 s, control = 1.92 ± 0.48 s, p = 0.07).ConclusionClinicians might use SRS to facilitate balance improvements with sagittal plane dynamic single leg balance exercises that patients may not be able to perform otherwise. 相似文献
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Woo Taek Kim Sung Gyun Ahn Jun-Won Lee Joong Kyung Sung Seung Hwan Lee Junghan Yoon 《Journal of Zhejiang University. Science. B》2010,11(8):627-630
It is a challenge to confirm chronic mesenteric ischemia (CMI) as a cause of gastrointestinal (Gl) symptoms such as postprandial epigastric bloating,anorexia,and debilitating weight loss.Endovascular intervention for CMI has been gaining popularity because of the high morbidity associated with surgical revascularization.However,in EVI for superior mesenteric artery (SMA) occlusion,the transfemoral approach is limited by difficulty in coaxial alignment of the guiding catheter,which leads to insufficient back-up support.Herein,we report on a 58-year-old male patient with chronic total occlusion of the SMA,which was successfully revascularized by endovascular intervention via the left radial artery.Transradial endovascutar therapy may be another treatment option for the treatment of CMI. 相似文献