| 耐力训练及限制饮食对单纯性肥胖大鼠脂肪合成的影响 |
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| 引用本文： | 王立靖,衣雪洁.耐力训练及限制饮食对单纯性肥胖大鼠脂肪合成的影响[J].北京体育大学学报,2008,31(9). |
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| 作者姓名： | 王立靖 衣雪洁 |
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| 作者单位： | 1. 东南大学体育系,江苏,南京,210096
2. 沈阳体育学院,辽宁,沈阳,110032 |
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| 摘 要： | 为探讨运动及限制饮食对单纯性肥胖大鼠脂合成的影响,将大鼠随机分为四组:正常饮食对照组(ND),高脂饮食非运动组(HN),高脂饮食运动组(HE)和限制高脂饮食运动组(LE)。造肥胖模型后对HE和LE组实行游泳耐力训练,期间LE组进行限制性高脂饮食。10周后,测定其体重、体长、脂肪垫重量,并测定其肝组织乙酰CoA羧化酶(ACC)基因表达、甘油三酯、血胰岛素及极低密度脂蛋白水平。游泳训练后,HE和LE组ACC基因表达比HN组分别下降19.6%和36.3%,大鼠体重及体脂百分比也显著下降;LE组甘油三酯、血胰岛素和极低密度脂蛋白水平显著降低。且LE组甘油三酯含量比HE组显著下降。耐力训练降低了大鼠脂类的合成,结合限制饮食使这种趋势更明显,减肥效果更好。
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| 关 键 词： | 单纯性肥胖 运动 饮食 乙酰CoA羧化酶 |
Influence of Endurance Training and Food-Restriction on Fat Synthesis in Rats with Simple Obesity |
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| WANG Li-jing,YI Xue-jie.Influence of Endurance Training and Food-Restriction on Fat Synthesis in Rats with Simple Obesity[J].Journal of Beijing Sport University,2008,31(9). |
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| Authors: | WANG Li-jing YI Xue-jie |
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| Abstract: | To explore the effects of endurance training and food-restriction on fat synthesis,we divide rats into four groups randomly: Normal diet contrast group(ND),high fat diet non-exercise group(HN),high fat diet exercise group(HE) and high-fat diet-limiting exercise group(LE).After making fat rats model, rats of HE and LE groups are trained to swim,and rats of LE group go on the restricted-high fat diet during this time.we measure their weight,the length of bodies,fat cushion weight,and also determine the level of acetyl CoA carboxyl enzyme(ACC) gene expression,triglyceride in rats liver,and the level of blood insulin,very low-density lipoprotein.10 weeks later,ACC gene expression is 19.6% and 36.3% in HE and LE groups lower than that in HN group,and the rats weight and body fat content decreases remarkably too.The level of liver triglyceride,blood insulin,and very low-density lipoprotein in LE group decrease remarkably.Moreover,the liver triglyceride level of LE group decreases remarkably compared with HE group.Endurance training reduces fat synthesis,and it is has a more effective function if combined with food-restriction. |
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| Keywords: | simple obesity exercise diet Acetyl CoA carboxyl enzyme |
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