| 有氧运动训练延缓小鼠大脑老化的生化研究 |
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| 引用本文： | 陈彩珍,卢健,许永刚,赖荣兴.有氧运动训练延缓小鼠大脑老化的生化研究[J].广州体育学院学报,2001,21(2):25-27,87. |
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| 作者姓名： | 陈彩珍 卢健 许永刚 赖荣兴 |
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| 作者单位： | 广州体育学院科研所、运动生化室 |
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| 摘 要： | 通过对小鼠大脑线粒体形态功能及抗氧化水平的观察研究，旨在探讨大脑老化的过程、机理及有氧运动对其的影响。研究发现，老龄小鼠大脑线粒体数量减少、体积增大，呼吸链酶活性下降，氧化与抗氧化系统失衡，脂褐素含量增多；有氧运动训练能增强大脑抗氧化防御机能，延缓大脑线粒体伴随衰老出现的能量转换效率的下降。
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| 关 键 词： | 有氧运动训练 大脑老化 线粒体形态 呼吸控制率 抗氧化能力 小鼠 生物化学 |
| 文章编号： | 1007-323(2001)02-0025-03 |
Biochemical Study on Effect of Aerobic Training of the Aging Brain |
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| CHEN Cai_zhen,LU Jian,XU Yong_gang,LAI Rong_xing.Biochemical Study on Effect of Aerobic Training of the Aging Brain[J].Journal of Guangzhou Physical Education Institute,2001,21(2):25-27,87. |
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| Authors: | CHEN Cai_zhen LU Jian XU Yong_gang LAI Rong_xing |
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| Abstract: | The present study observes effects of aerobic training on the age_related changes of mice brain mitochondria morphology,function and antioxidant activity.The results showed that the number of mitochondria reduced,and the volume increased.Mitochondrial respiratory chain enzymes activities declined with age,and the system of oxidant and antioxidant was imbalance.Adaptive changes of mitochondria were brought by aerobic training which might delay the age_related decline of mitochondrial function in brain. |
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| Keywords: | aerobic training aging brain mitochondria RCR antioxidant |
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