| 不同低氧训练模式对大鼠大脑环磷酸腺苷及自由基代谢的影响 |
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| 引用本文： | 王仁纲,林文弢,梁伟,翁锡全.不同低氧训练模式对大鼠大脑环磷酸腺苷及自由基代谢的影响[J].首都体育学院学报,2011,23(3):275-277,284. |
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| 作者姓名： | 王仁纲 林文弢 梁伟 翁锡全 |
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| 作者单位： | 1. 广州体育学院运动生化省重点实验室,广东广州,510500
2. 广东暨南大学,广州,510632 |
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| 摘 要： | 探讨不同低氧训练模式对大鼠大脑环磷酸腺苷(cAMP)及自由基代谢的变化影响,为低氧训练方法的选择提供理论依据。将8周龄健康雄性SD大鼠37只,随机分为常氧运动组、高住高练组、高住低练组和低住高练组共4组,低氧环境控制在15.4%O2左右,训练组常氧跑步速度为25 m/min,低氧下跑步速度为20 m/min,1 h/d,6 d/w,训练持续4周后测试大脑cAMP、SOD和MDA含量。结果发现:与常氧组比较,高住低练组与高练低住组cAMP均有升高的趋势,但经统计学检验均无显著差异(P>0.05);高住低练组与高练低住组SOD活性显著高于高住高练组和常氧运动组(P<0.05),而高住高练组、高住低练组与高练低住组MDA均明显低于常氧运动组(P<0.05)。结论:4周的高住高练、高住低练和低住高练能提高大鼠脑抗氧化能力,有利于脑机能保持在正常水平,且高练低住和高住低练效果较高住高练好,更有利于脑cAMP含量的保持。
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| 关 键 词： | 低氧训练 大鼠 脑 cAMP SOD MDA |
Effects of Different Hypoxia Training Methods on Brain cAMP and Free Radical Metabolism of Rats |
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| WANG Rengang,LIN Wentao,LIANG Wei,WENG Xiquan.Effects of Different Hypoxia Training Methods on Brain cAMP and Free Radical Metabolism of Rats[J].Journal of Capital College of Physical Education,2011,23(3):275-277,284. |
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| Authors: | WANG Rengang LIN Wentao LIANG Wei WENG Xiquan |
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| Institution: | WANG Rengang1,LIN Wentao1,LIANG Wei2,WENG Xiquan1 1.Science Experimental Center,Guangzhou Sport University,Guangzhou 510500,China,2.Jinan University,Guangzhou 510632,China. |
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| Abstract: | Objective:To substantiate the effects of different hypoxia training methods on brain cAMP and free radical of rats.Methods:37 male Sprague-Drawly(SD) rats(180~220g body weight) were randomly divided into 4 groups:training at low altitude(LL),living high-training high(HH),living high and training low(HL),living low and training high(LH).In the hypoxic environment the oxygen content was 15.4%.The rats were trained on a treadmill using a progressive protocol that plateau at 25m/min in normal environment and at... |
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| Keywords: | hypoxia training rat brain cAMP SOD MDA |
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