| 疲劳应激大鼠杏仁皮质内侧核群一氧化氮合酶阳性神经元的变化 |
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| 引用本文： | 刘鸿宇,曹电康,侯宏花,付芳,王晓东.疲劳应激大鼠杏仁皮质内侧核群一氧化氮合酶阳性神经元的变化[J].北京体育大学学报,2005,28(8):1086-1088. |
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| 作者姓名： | 刘鸿宇 曹电康 侯宏花 付芳 王晓东 |
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| 作者单位： | 中北大学,山西,太原,030051 |
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| 基金项目： | 中北大学校科研和教改项目 |
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| 摘 要： | 为了探讨杏仁皮质内侧核群一氧化氮合酶(NOS)与运动疲劳应激的关系,观察了运动疲劳应激对大鼠杏仁皮质内侧核群NOS阳性神经元中神经元型一氧化氮合酶(nNOS)表达的影响.结果发现:疲劳组大鼠杏仁皮质前核(Aco)、杏仁内侧核(Me)和杏仁中央核(Ce)中nNOS阳性神经元数量和面积均小于对照组(P<0.05,P<0.01) ,其中疲劳组杏仁中央核(Ce)中 nNOS阳性神经元的灰度值也明显小于对照组(P<0.01).表明:疲劳应激可使大鼠杏仁皮质内侧核群神经元中的nNOS下调,杏仁皮质内侧核群nNOS神经元参与了中枢运动性疲劳的形成,其机理可能与杏仁皮质内侧核群神经元对应激反应的心理、行为、内分泌调节有关.
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| 关 键 词： | 应激 运动性疲劳 杏仁皮质内侧核 神经元型一氧化氮合酶(nNOS) 大鼠 性疲劳 应激大鼠 杏仁中央核 皮质内侧核群 一氧化氮合酶 阳性神经元 变化 Fatigue Stress Rats Neurons Nitric Oxide Changes 内分泌调节 行为 心理 应激反应 机理 中枢 灰度值 |
| 文章编号： | 1007-3612(2005)08-1086-03 |
| 修稿时间： | 2004年6月7日 |
Research on Changes of the Nitric Oxide Synthase-positive Neurons in Medial Cortical Amygdaloid Nuclei of Rats under Stress of Exercise-induced Fatigue |
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| LIU Hong-yu,CAO Dian-kang,HOU Hong-hua,Fu Fang,WANG Xiao-dong.Research on Changes of the Nitric Oxide Synthase-positive Neurons in Medial Cortical Amygdaloid Nuclei of Rats under Stress of Exercise-induced Fatigue[J].Journal of Beijing Sport University,2005,28(8):1086-1088. |
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| Authors: | LIU Hong-yu CAO Dian-kang HOU Hong-hua Fu Fang WANG Xiao-dong |
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| Abstract: | In order to explore the relationship between stress of exercise-induced fatigue and nitric oxide synthase (NOS) in medial cortical amygdaloid nuclei, it was observed that the effects of stress of exercise-induced fatigue on expression of nNOS in the nitric oxide synthase-positive neurons in rat medial cortical amygdaloid nuclei. The results show that a signifi- cant decrease of nNOS positive neurons in anterior cortical amygdaloid nucleus (Aco),medial amygdaloid nucleus (Me), central amygdaloid nucleus(Ce) in the number and area in fatigue group (P<0.05,P<0.01), and a significant decrease of nNOS positive neurons in Ce in gray degree in fatigue group (P<0.01). It is concluded that stress of exercise-induced fatigue can induce downregulated expression of nNOS in medial cortical amygdaloid nuclei which were involved in forming of exercise-induced central fatigue, due to the psychological, behavioral, and endocrine regulation of amygdaloid nuclei on stress. |
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| Keywords: | stress exercise-induced fatigue medial cortical amygdaloid nuclei neuronal nitric oxide synthase (nNOS) rat |
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