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| 健脾补糖对过度训练脾虚大鼠骨骼肌GLUT4和P38活性的影响 | |
| 引用本文： | 衣雪洁,张庆荣,于莹.健脾补糖对过度训练脾虚大鼠骨骼肌GLUT4和P38活性的影响[J].北京体育大学学报,2007,30(9):1212-1215. |
| 作者姓名： | 衣雪洁 张庆荣 于莹 |
| 作者单位： | 1. 沈阳体育学院运动人体科学系,辽宁,沈阳,110102 2. 辽宁中医药大学中医基础理论教研室,辽宁,沈阳,110032 3. 哈尔滨体育学院运动生化教研室,黑龙江,哈尔滨,150011 |
| 摘 要： | 为了探讨健脾补糖对过度训练大鼠骨骼肌的糖转运和MAPK转导通路中P38活性的影响.通过6周递增大负荷游泳训练,观察过度训练和健脾补糖对胃肠的吸收功能,骨骼肌的糖转运、储备和P38活性的影响.研究表明:1)过度训练脾虚的大鼠的骨骼肌MAPK信号转导系统的P38途径虽然被激活.但骨骼肌的葡萄糖转运和糖储存被低血糖和胰岛素所抑制.因此没有明显改善骨骼肌的肌糖原储备.2)健脾补糖从改善胃肠功能、增加能源物质的摄入、提高抗氧化能力等多靶点激活了P38,使骨骼肌对葡萄糖的转运速度与合成速度均加快,在末次运动后24 h就使肌糖原达到了明显的超量恢复状态. |
| 关 键 词： | 健脾补糖 过度训练 脾虚 骨骼肌 GLUT4 P38 活性 健脾 补糖 过度训练 脾虚 大鼠骨骼肌 活性 影响 Rats Saccharide Spleen Effects Activity 状态 超量恢复 肌糖原 运动后 合成速度 葡萄糖转运 多靶点 氧化能力 |
Effects of Invigorating Spleen and Supplying Saccharide on Overtrained Rats' Skeletal Muscle GLUT4 and P38 Activity |
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| YI Xue-jie,ZHANG Qing-rong,YU Ying.Effects of Invigorating Spleen and Supplying Saccharide on Overtrained Rats'''' Skeletal Muscle GLUT4 and P38 Activity[J].Journal of Beijing Sport University,2007,30(9):1212-1215. | |
| Authors: | YI Xue-jie ZHANG Qing-rong YU Ying |
| Abstract: | The study focuses on how invigorating the spleen and supplying saccharide affect glucose transport in the skeletal muscle and P38 activity in MAPK signal transduction system of overtrained rats.All groups of rats are trained by increasing load of swimming for 6 weeks,and to observe effects of invigorating spleen and supplying saccharide on function of the stomach and intestine,glucose transport and storage in the skeletal muscle and P38 activity.It draws a conclusion that 1)Rats of spleen asthenia sports fatigue activates the P38 pathways in MAPK signal transduction passageway in the skeletal muscle.Meanwhile,hypoglycemia and insulin suppress glucose transport and storage in the skeletal muscle.So it is not very significant in the muscle glycogen store increase.2)Training with invigorating spleen and supplying saccharine may lead to improve stomach and intestine,intake augmentation of energy source substrates,and enhance saccharide oxidation capability in the multi-target.Besides,it plays an important part in the P38 pathways in the MAPK signal transduction system,which may speed up glucose transport and synthesis in the skeletal muscle,and result in the over-recovery of muscle glycogen. |
| Keywords: | invigorating spleen and supplying saccharide overload training weakness of spleen skeletal muscle GLUT4 P38 activity |
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