| 补充海洋肽对大鼠骨骼肌bFGF及Desmin的作用 |
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| 引用本文： | 姚燕,王启荣,安江红,杨锐睿,邵晶,高红,周越.补充海洋肽对大鼠骨骼肌bFGF及Desmin的作用[J].北京体育大学学报,2011,34(6):50-53. |
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| 作者姓名： | 姚燕 王启荣 安江红 杨锐睿 邵晶 高红 周越 |
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| 作者单位： | 北京体育大学;国家体育总局运动医学研究所;北京市体育科学研究所; |
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| 基金项目： | 北京市科技计划项目“运动员营养品的开发和应用研究——海洋肽在运动性骨胳肌损伤修复中的应用及其机制研究”(D0606002040431); 北京市重点实验室(运动机能评定与技术分析实验室)开放研究课题(2007-006) |
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| 摘 要： | 目的:观察适应性训练、补充海洋肽以及大豆蛋白后骨骼肌bFGF及desmin含量的变化,研究运动训练、补充海洋肽以及大豆蛋白对运动性肌肉损伤和修复的影响。方法:以雄性SD大鼠72只,随机分为:安静组、运动组、运动+海洋肽组、运动+大豆蛋白组。进行6周适应性离心运动训练即-5°下坡间歇跑,跑速从20.0 m/min递增至35.0 m/min,每次10~20 min,每周训练5 d,之后给予定量离心负荷,分别取运动后即刻、24 h和48 h不同时间处死、取股中间肌、测试。结果:6周适应性训练可以增强desmin的适应能力。补充海洋肽组股中间肌desmin蛋白丢失较少。补充大豆蛋白组运动后即刻bFGF蛋白表达量显著性低于安静组,运动后48 h组bFGF蛋白表达量显著性高于运动后即刻组。结论:补充海洋肽能够更好的减少离心运动后骨架蛋白的丢失,促进运动后骨骼肌损伤的修复。
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| 关 键 词： | 海洋肽 离心运动 bFGF desmin |
Effects of Marine Peptide Supplementation on bFGF and Desmin in Skeletal Muscle of Rat |
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| YAO Yan,WANG Qi-rong,AN Jiang-hong,YANG Rui-rui,SHAO Jing,GAO Hong,ZHOU Yue.Effects of Marine Peptide Supplementation on bFGF and Desmin in Skeletal Muscle of Rat[J].Journal of Beijing Sport University,2011,34(6):50-53. |
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| Authors: | YAO Yan WANG Qi-rong AN Jiang-hong YANG Rui-rui SHAO Jing GAO Hong ZHOU Yue |
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| Institution: | YAO Yan1,WANG Qi-rong2,AN Jiang-hong3,YANG Rui-rui1,SHAO Jing2,GAO Hong2,ZHOU Yue1(1.Beijing Sport University,Beijing 100084,China,2.National Institute of Sports Medicine Beijing,100029,3.Beijing Institute of Sports Science,Beijing 100075,China) |
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| Abstract: | Objective: To investigate effect of training,the marine bioactive peptide and soybean protein supplementation on content changes of desmin and bFGF after eccentric exercise in rats.Methods: Male SD rats were randomly divided into non-exercise control group and three training groups: group of supplying marine bioactive peptide,group of supplying soybean protein and group of supplying water.In 6-wk training with five days/wk,the speed raised from 20.0m/min to 35.0m/min,and the grade was always-5°.In the seventh week,the tissues were collected separately at 0h,24h and 48h after eccentric exercise.Results: 1.The desmin content decreased at 0h and began to rise at 48h after eccentric exercise.2.Supplying soybean protein could reduce the loss of desmin.3.bFGF protein content increased earlier than desmin.Conclusion: Supplying soybean protein can repair desmin after eccentric exercise to some extent.Supplying marine bioactive peptide can reduce the loss of desmin better,but not by regulating bFGF. |
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| Keywords: | marine bioactive peptide eccentric exercise bFGF desmin |
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