| 运动与细胞凋亡 |
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| 引用本文： | 沈志祥.运动与细胞凋亡[J].山西师大体育学院学报,2004,19(3):80-82,105. |
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| 作者姓名： | 沈志祥 |
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| 作者单位： | 华东师范大学体育与健康学院,上海,200062 |
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| 摘 要： | 本文采用文献资料法对运动与细胞凋亡的研究现状及进展进行研究探讨。着重分析了凋亡相关基因、自由基和线粒体在细胞凋亡形成中的作用及可能机理，以及运动对细胞凋亡的影响。运动可以诱导细胞凋亡，细胞凋亡发生的比率和程度与运动形式、运动强度和运动持续时间有关，其机制可能主要包括以下方面：影响凋亡相关基因、自由基的介导使氧化与抗氧化系统失衡，损伤线粒体的结构和功能以及机械损伤。
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| 关 键 词： | 体育运动 细胞凋亡 自由基 运动强度 运动形式 运动时间 形态学 生物化学 |
| 文章编号： | 1008-8571(2004)03-0080-04 |
| 修稿时间： | 2004年5月8日 |
Exercise and the Apoptosis of the Cell |
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| SHEN ZHi-xiang.Exercise and the Apoptosis of the Cell[J].Journal of Physical Education Institute of Shanxi Teachers University,2004,19(3):80-82,105. |
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| Authors: | SHEN ZHi-xiang |
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| Abstract: | Progress and current status of the cellular apoptosis relating to exercise were discussed by means of consulting literature. The stress discussions consisted of apoptosis-related gene, the actions and mechanisms of free racial and mitochondria in the apoptosis process of cell respectively, as well as actions of exercise. Apoptosis of cell was induced by exercise and the incidence and level of apoptosis related to the mode, intensity and sustained time of exercise. The main possible mechanisms consisted of the followings: factors of apoptosis-related gene, free radical inducing resulted unequilibrium between oxidant and antioxidant system, mitochondrial structure and function injury, as well as mechanical injury. |
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| Keywords: | exercise apoptosis aging |
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