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1.
Geometry and topology are fundamental concepts, which underlie a wide range of fascinating physical phenomena such as topological states of matter and topological defects. In quantum mechanics, the geometry of quantum states is fully captured by the quantum geometric tensor. Using a qubit formed by an NV center in diamond, we perform the first experimental measurement of the complete quantum geometric tensor. Our approach builds on a strong connection between coherent Rabi oscillations upon parametric modulations and the quantum geometry of the underlying states. We then apply our method to a system of two interacting qubits, by exploiting the coupling between the NV center spin and a neighboring 13C nuclear spin. Our results establish coherent dynamical responses as a versatile probe for quantum geometry, and they pave the way for the detection of novel topological phenomena in solid state.  相似文献   

2.
This paper investigates the mixed H and passive control problem for a class of nonlinear switched systems based on a hybrid control strategy. To solve this problem, firstly, using the Takagi–Sugeno (T–S) fuzzy model to approximate every nonlinear subsystem, the nonlinear switched systems are modeled as the switched T–S fuzzy systems. Secondly, the hybrid controllers are used to stabilize the switched T–S fuzzy systems. The hybrid controllers consist of dynamic output-feedback controllers for every subsystem and state updating controllers at the switching instant. Thirdly, a new performance index is proposed for switched systems. This new performance index can be viewed as the mixed weighted H and passivity performance. Based on this new performance index, the weighted H control problem and the passive control problem for switched T–S fuzzy systems via the hybrid control strategy are solved in a unified framework. Together the multiple Lyapunov functions (MLFs) approach with the average dwell time (ADT) technique, new design conditions for the hybrid controllers are obtained. Under these conditions, the closed-loop switched T–S fuzzy systems are globally uniformly asymptotically stable with a prescribed mixed H and passivity performance index. Moreover, the desired hybrid controllers can be constructed by solving a set of linear matrix inequalities (LMIs). Finally, the effectiveness of the obtained results is illustrated by a numerical example.  相似文献   

3.
A numerical modeling of natural convection under the influence of either axial (Bz) or radial (Br) magnetic field in a cylindrical configuration filled with a low-Prandtl number electrically conducting fluid, is studied. The finite volume method is used to discretize the equations of continuity, Navier Stokes and energy. A computer program based on the SIMPLER algorithm is developed. The flow and temperature fields are presented by stream function and isotherms, respectively. Stability diagrams are established according to the numerical results of this investigation. These diagrams put in evidence the dependence of the critical Grashof number, Grcr with the increase of the Hartmann number, Ha. The strongest stabilization of the convective flows occurs when the magnetic field is applied in the radial direction. This study confirms the possibility of stabilization of a liquid metal flow in natural convection by application of a radial magnetic field.  相似文献   

4.
Carbon is one of the most fascinating elements due to its structurally diverse allotropic forms stemming from its bonding varieties (sp, sp2 and sp3). Exploring new forms of carbon has been the eternal theme of scientific research. Herein, we report on amorphous (AM) carbon materials with a high fraction of sp3 bonding recovered from compression of fullerene C60 under high pressure and high temperature, previously unexplored. Analysis of photoluminescence and absorption spectra demonstrates that they are semiconducting with a bandgap range of 1.5–2.2 eV, comparable to that of widely used AM silicon. Comprehensive mechanical tests demonstrate that synthesized AM-III carbon is the hardest and strongest AM material known to date, and can scratch diamond crystal and approach its strength. The produced AM carbon materials combine outstanding mechanical and electronic properties, and may potentially be used in photovoltaic applications that require ultrahigh strength and wear resistance.  相似文献   

5.
One of the most significant challenges implementing colloidal magnetic nanoparticles in medicine is the efficient heating of microliter quantities by applying a low frequency alternating magnetic field. The ultimate goal is to accomplish nonsurgically the treatment of millimeter size tumors. Here, we demonstrate the synthesis, characterization, and the in vitro as well as in vivo efficiency of a dextran coated maghemite (γ-Fe2O3) ferrofluid with an exceptional response to magnetic heating. The difference to previous synthetic attempts is the high charge of the dextran coating, which according to our study maintains the colloidal stability and good dispersion of the ferrofluid during the magnetic heating stage. Specifically, in vitro 2 μl of the ferrofluid gives an outstanding temperature rise of 33 °C within 10 min, while in vivo treatment, by infusing 150 μl of the ferrofluid in animal model (rat) glioma tumors, causes an impressive cancer tissue dissolution.  相似文献   

6.
Mechanically exfoliated two-dimensional ferromagnetic materials (2D FMs) possess long-range ferromagnetic order and topologically nontrivial skyrmions in few layers. However, because of the dimensionality effect, such few-layer systems usually exhibit much lower Curie temperature (TC) compared to their bulk counterparts. It is therefore of great interest to explore effective approaches to enhance their TC, particularly in wafer-scale for practical applications. Here, we report an interfacial proximity-induced high-TC 2D FM Fe3GeTe2 (FGT) via A-type antiferromagnetic material CrSb (CS) which strongly couples to FGT. A superlattice structure of (FGT/CS)n, where n stands for the period of FGT/CS heterostructure, has been successfully produced with sharp interfaces by molecular-beam epitaxy on 2-inch wafers. By performing elemental specific X-ray magnetic circular dichroism (XMCD) measurements, we have unequivocally discovered that TC of 4-layer Fe3GeTe2 can be significantly enhanced from 140 K to 230 K because of the interfacial ferromagnetic coupling. Meanwhile, an inverse proximity effect occurs in the FGT/CS interface, driving the interfacial antiferromagnetic CrSb into a ferrimagnetic state as evidenced by double-switching behavior in hysteresis loops and the XMCD spectra. Density functional theory calculations show that the Fe-Te/Cr-Sb interface is strongly FM coupled and doping of the spin-polarized electrons by the interfacial Cr layer gives rise to the TC enhancement of the Fe3GeTe2 films, in accordance with our XMCD measurements. Strikingly, by introducing rich Fe in a 4-layer FGT/CS superlattice, TC can be further enhanced to near room temperature. Our results provide a feasible approach for enhancing the magnetic order of few-layer 2D FMs in wafer-scale and render opportunities for realizing realistic ultra-thin spintronic devices.  相似文献   

7.
As a non-invasive therapeutic method without penetration-depth limitation, magnetic hyperthermia therapy (MHT) under alternating magnetic field (AMF) is a clinically promising thermal therapy. However, the poor heating conversion efficiency and lack of stimulus–response obstruct the clinical application of magnetofluid-mediated MHT. Here, we develop a ferrimagnetic polyethylene glycol-poly(2-hexoxy-2-oxo-1,3,2-dioxaphospholane) (mPEG-b-PHEP) copolymer micelle loaded with hydrophobic iron oxide nanocubes and emodin (denoted as EMM). Besides an enhanced magnetic resonance (MR) contrast ability (r2 = 271 mM−1 s−1) due to the high magnetization, the specific absorption rate (2518 W/g at 35 kA/m) and intrinsic loss power (6.5 nHm2/kg) of EMM are dozens of times higher than the clinically available iron oxide nanoagents (Feridex and Resovist), indicating the high heating conversion efficiency. Furthermore, this composite micelle with a flowable core exhibits a rapid response to magnetic hyperthermia, leading to an AMF-activated supersensitive drug release. With the high magnetic response, thermal sensitivity and magnetic targeting, this supersensitive ferrimagnetic nanocomposite realizes an above 70% tumor cell killing effect at an extremely low dosage (10 μg Fe/mL), and the tumors on mice are completely eliminated after the combined MHT–chemotherapy.  相似文献   

8.
Robust fault detection for a class of nonlinear time-delay systems   总被引:1,自引:0,他引:1  
In this paper, the robust fault detection filter (RFDF) design problems are studied for nonlinear time-delay systems with unknown inputs. Firstly, a reference residual model is introduced to formulate the robust fault detection filter design problem as an H model-matching problem. Then appropriate input/output selection matrices are introduced to extend a performance index to the time-delay systems in time domain. The reference residual model designed according to the performance index is an optimal residual generator, which takes into account the robustness against disturbances and sensitivity to faults simultaneously. Applying robust H optimization control technique, the existence conditions of the robust fault detection filter for nonlinear time-delay systems with unknown inputs are presented in terms of linear matrix inequality (LMI) formulation, independently of time delay. An illustrative design example is used to demonstrate the validity and applicability of the proposed approach.  相似文献   

9.
We report differential phase contrast scanning transmission electron microscopy (TEM) of nanoscale magnetic objects in Kagome ferromagnet Fe3Sn2 nanostructures. This technique can directly detect the deflection angle of a focused electron beam, thus allowing clear identification of the real magnetic structures of two magnetic objects including three-ring and complex arch-shaped vortices in Fe3Sn2 by Lorentz-TEM imaging. Numerical calculations based on real material-specific parameters well reproduced the experimental results, showing that the magnetic objects can be attributed to integral magnetizations of two types of complex three-dimensional (3D) magnetic bubbles with depth-modulated spin twisting. Magnetic configurations obtained using the high-resolution TEM are generally considered as two-dimensional (2D) magnetic objects previously. Our results imply the importance of the integral magnetizations of underestimated 3D magnetic structures in 2D TEM magnetic characterizations.  相似文献   

10.
This paper deals with the stability and dissipative problem of a class of stochastic hybrid system. The system under study involves Markovian jump, impulsive effects and time delay, which are often encountered in practice and are the sources of instability. Our attention is focused on analysis of whether the stochastic hybrid system with time-delay is stochastically asymptotically stable and strictly (Q, S, R) dissipative. By introducing an extra artificial time instance, the equivalent system is obtained and the sufficient conditions are derived by using linear matrix inequality (LMI) techniques. The main results of this paper unify the existing results on H control.  相似文献   

11.
Unwanted sedimentation and attachment of a number of cells onto the bottom channel often occur on relatively large-scale inlets of conventional microfluidic channels as a result of gravity and fluid shear. Phenomena such as sedimentation have become recognized problems that can be overcome by performing microfluidic experiments properly, such as by calculating a meaningful output efficiency with respect to real input. Here, we present a dual-inlet design method for reducing cell loss at the inlet of channels by adding a new “ upstream inlet ” to a single main inlet design. The simple addition of an upstream inlet can create a vertically layered sheath flow prior to the main inlet for cell loading. The bottom layer flow plays a critical role in preventing the cells from attaching to the bottom of the channel entrance, resulting in a low possibility of cell sedimentation at the main channel entrance. To provide proof-of-concept validation, we applied our design to a microfabricated flow cytometer system (μFCS) and compared the cell counting efficiency of the proposed μFCS with that of the previous single-inlet μFCS and conventional FCS. We used human white blood cells and fluorescent microspheres to quantitatively evaluate the rate of cell sedimentation in the main inlet and to measure fluorescence sensitivity at the detection zone of the flow cytometer microchip. Generating a sheath flow as the bottom layer was meaningfully used to reduce the depth of field as well as the relative deviation of targets in the z-direction (compared to the x-y flow plane), leading to an increased counting sensitivity of fluorescent detection signals. Counting results using fluorescent microspheres showed both a 40% reduction in the rate of sedimentation and a 2-fold higher sensitivity in comparison with the single-inlet μFCS. The results of CD4+ T-cell counting also showed that the proposed design results in a 25% decrease in the rate of cell sedimentation and a 28% increase in sensitivity when compared to the single-inlet μFCS. This method is simple and easy to use in design, yet requires no additional time or cost in fabrication. Furthermore, we expect that this approach could potentially be helpful for calculating exact cell loading and counting efficiency for a small input number of cells, such as primary cells and rare cells, in microfluidic channel applications.  相似文献   

12.
This paper investigates an H2/H filter designing for networked systems perturbed by multiple noises. The measurement transmission from the sensor to the remote filter is completed via a communication network in simultaneously presenting of data transmission time-varying delays, data packet dropout and data sequence disorder. Since the filter will receive delayed and disordered information, a zero-order-hold (ZOH) or a logical-ZOH (LZOH) is firstly employed for resorting the chaos data sequence. Afterwards, a hybrid H2/H filtering scheme is designed for accurately estimating the target output. By Itô formula and a novel free-weight method, the almost surely mean square exponentially stable (ASMSES) condition of the error system is conveniently obtained and the corresponding filter design method is finally presented. By the proposed method, not only the ASMSES with a pre-scheduled H2/H performance can be achieved, but also the convergence rate of overall system is pre-regulable. In addition, it has been point out the dynamic filtering performance of LZOH scheme should be better than ZOH ones due to less time-varying delays are introduced and more latest measurement information are employed. Numerical examples are provided to demonstrate the effectiveness of the proposed methods.  相似文献   

13.
澜沧江流域潜在蒸散发敏感性分析   总被引:3,自引:1,他引:3  
蒸散发对气候变量的敏感性研究是近年来水文学的热点之一,对探讨水循环对气候变化的响应具有重要意义。本文利用1960年-2005年澜沧江流域及其周边35个气象站的逐日常规气象观测数据,基于Penman-Monteith公式,计算了1月、7月及年3个不同时间尺度下潜在蒸散发对平均气温、相对湿度、风速及日照时数的敏感系数,分析了澜沧江流域潜在蒸散发对各气候变量的敏感性及其时空变化规律。结果表明各站潜在蒸散发对各变量的敏感系数空间分异明显,流域整体上对日照时数最为敏感。几十年来对日照时数的敏感性在1月主要为增加趋势,7月则为减小趋势。  相似文献   

14.
Iron-based superconductors have been identified as a novel platform for realizing Majorana zero modes (MZMs) without heterostructures, due to their intrinsic topological properties and high-Tc superconductivity. In the two-dimensional limit, the FeTe1−xSex monolayer, a topological band inversion has recently been experimentally observed. Here, we propose to create MZMs by applying an in-plane magnetic field to the FeTe1−xSex monolayer and tuning the local chemical potential via electric gating. Owing to the anisotropic magnetic couplings on edges, an in-plane magnetic field drives the system into an intrinsic high-order topological superconductor phase with Majorana corner modes. Furthermore, MZMs can occur at the domain wall of chemical potentials at either one edge or certain type of tri-junction in the two-dimensional bulk. Our study not only reveals the FeTe1−xSex monolayer as a promising Majorana platform with scalability and electrical tunability and within reach of contemporary experimental capability, but also provides a general principle to search for realistic realization of high-order topological superconductivity.  相似文献   

15.
To develop a lab on a chip (LOC) integrated with both sensor and actuator functions, a novel two-in-one system based on optical-driven manipulation and sensing in a microfluidics setup based on a hydrogenated amorphous silicon (a-Si:H) layer on an indium tin oxide/glass is first realized. A high-intensity discharge xenon lamp functioned as the light source, a chopper functioned as the modulated illumination for a certain frequency, and a self-designed optical path projected on the digital micromirror device controlled by the digital light processing module was established as the illumination input signal with the ability of dynamic movement of projected patterns. For light-addressable potentiometric sensor (LAPS) operation, alternating current (AC)-modulated illumination with a frequency of 800 Hz can be generated by the rotation speed of the chopper for photocurrent vs bias voltage characterization. The pH sensitivity, drift coefficient, and hysteresis width of the Si3N4 LAPS are 52.8 mV/pH, −3.2 mV/h, and 10.5 mV, respectively, which are comparable to the results from the conventional setup. With an identical two-in-one system, direct current illumination without chopper rotation and an AC bias voltage can be provided to an a-Si:H chip with a manipulation speed of 20 μm/s for magnetic beads with a diameter of 1 μm. The collection of magnetic beads by this light-actuated AC electroosmosis (LACE) operation at a frequency of 10 kHz can be easily realized. A fully customized design of an illumination path with less decay can be suggested to obtain a high efficiency of manipulation and a high signal-to-noise ratio of sensing. With this proposed setup, a potential LOC system based on LACE and LAPS is verified with the integration of a sensor and an actuator in a microfluidics setup for future point-of-care testing applications.  相似文献   

16.
BackgroundAt present, cellulases are the most important enzymes worldwide, and their demand has been increasing in the industrial sector owing to their notable hydrolysis capability.ResultsIn the present study, contrary to conventional techniques, three physical parameters were statistically optimized for the production of cellulase by thermophilic fungi by using response surface methodology (RSM). Among all the tested thermophilic strains, the best cellulase producing fungus was identified as Talaromyces thermophilus – both morphologically and molecularly through 5.8S/ITS rDNA sequencing. The central composite design (CCD) was used to evaluate the interactive effect of the significant factors. The CCD was applied by considering incubation period, pH, and temperature as the model factors for the present investigation. A second-order quadratic model and response surface method revealed that the independent variables including pH 6, temperature 50 °C, and incubation period 72 h significantly influenced the production of cellulases. The analysis of variance (ANOVA) indicated that the established model was significant (P ≤ 0.05) and showed the high adequacy of the model. The actual and predicted values of CMCase and FPase activity showed good agreement with each other and also confirmed the validity of the designed model.ConclusionsWe believe the present findings to be the first report on cellulase production by exploiting Kans grass (Saccharum spontaneum) as a substrate through response surface methodology by using thermophilic fungus, Talaromyces thermophilus.How to cite: Abdullah R, Tahseen M, Nisar K et al. Statistical optimization of cellulases by Talaromyces thermophilus utilizing Saccharum spontaneum, a novel substrate. Electron J Biotechnol 2021;51. https://doi.org/10.1016/j.ejbt.2021.03.007.  相似文献   

17.
Spin defects in silicon carbide (SiC) with mature wafer-scale fabrication and micro/nano-processing technologies have recently drawn considerable attention. Although room-temperature single-spin manipulation of colour centres in SiC has been demonstrated, the typically detected contrast is less than 2, and the photon count rate is also low. Here, we present the coherent manipulation of single divacancy spins in 4H-SiC with a high readout contrast () and a high photon count rate (150 kilo counts per second) under ambient conditions, which are competitive with the nitrogen-vacancy centres in diamond. Coupling between a single defect spin and a nearby nuclear spin is also observed. We further provide a theoretical explanation for the high readout contrast by analysing the defect levels and decay paths. Since the high readout contrast is of utmost importance in many applications of quantum technologies, this work might open a new territory for SiC-based quantum devices with many advanced properties of the host material.  相似文献   

18.
This paper presents a simple and efficient design method for cosine-modulated filter banks with prescribed stopband attenuation, passband ripple, and channel overlap. The method casts the design problem as a linear minimization of filter coefficients such that their value at ω=π/2M is 0.707, which results in a simpler, more direct design procedure. The weighted constrained least squares technique is exploited for designing the prototype filter for cosine modulation (CM) filter banks. Several design examples are included to show the increased efficiency and flexibility of the proposed method over the exiting methods. An application of the proposed method is considered in the area of sub-band coding of the ECG and speech signals.  相似文献   

19.
A new feedback controller architecture is presented for linear systems with a single I/O delay in the generalized internal model control (GIMC) framework. According to the doubly coprime factorization of these systems, traditional GIMC strategy is extended to linear systems with a single I/O delay. The distinguished feature of the control system architecture is that high tracking performance and good external disturbance rejection could be done separately by a nominal Smith predictor part and a finite dimensional conditional controller. First, a nominal Smith predictor part could be designed to deal with command tracking performance. Second, according to the left coprime factorization of the nominal controller, a finite dimensional conditional controller could be considered for external disturbance rejection, when the controlled plant should be assumed to be a square one. Finally, a simple design example is illustrated the effectiveness of the presented method.Finally, a simple design example is illustrated the effectiveness of the presented method.  相似文献   

20.
Magnetic hyperthermia therapy (MHT) is able to ablate tumors using an alternating magnetic field (AMF) to heat up magnetocaloric agents (e.g. magnetic nanoparticles) administered into the tumors. For clinical applications, there is still a demand to find new magnetocaloric agents with strong AMF-induced heating performance and excellent biocompatibility. As a kind of biocompatible and biodegradable material, magnesium (Mg) and its alloys have been extensively used in the clinic as an implant metal. Herein, we discovered that the eddy thermal effect of the magnesium alloy (MgA) could be employed for MHT to effectively ablate tumors. Under low-field-intensity AMFs, MgA rods could be rapidly heated, resulting in a temperature increase in nearby tissues. Such AMF-induced eddy thermal heating of MgA could not only be used to kill tumor cells in vitro, but also be employed for effective and accurate ablation of tumors in vivo. In addition to killing tumors in mice, we further demonstrated that VX2 tumors of much larger sizes growing in rabbits after implantation of MgA rods could also be eliminated after exposure to an AMF, illustrating the ability of MgA-based MHT to kill large-sized tumors. Moreover, the implanted MgA rods showed excellent biocompatibility and ∼20% of their mass was degraded within three months. Our work thus discovered for the first time that non-magnetic biodegradable MgA, an extensively used implant metal in clinic, could be used for effective magnetic thermal ablation of tumors under a low-field-intensity AMF. Such a strategy could be readily translated into clinical use.  相似文献   

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