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1.
This investigation examined the oxidative stress (F2-Isoprostane; F2-IsoP) and inflammatory (interleukin-6; IL-6) responses to repeat-sprint training in hypoxia (RSH). Ten trained male team sport athletes performed 3(sets)*9(repetitions)*5?s cycling sprints in simulated altitude (3000?m) and sea-level conditions. Mean and peak sprint power output (MPO and PPO) were recorded, and blood samples were collected pre-exercise, and again at 8 and 60?min post-exercise. Both MPO and PPO were significantly reduced in hypoxia (compared to sea-level) in the second (MPO: 855?±?89 vs. 739?±?95?W, p?=?.006; PPO: 1024?±?114 vs. 895?±?112?W, p?=?.010) and third (MPO: 819?±?105 vs. 686?±?83?W, p?=?.008; PPO: 985?±?125 vs. 834?±?99?W, p?=?.008) sets, respectively. IL-6 was significantly increased from pre- to 1?h post-exercise in both hypoxia (0.7?±?0.2 vs. 2.4?±?1.4?pg/mL, p?=?.004) and sea-level conditions (0.7?±?0.2 vs. 1.6?±?0.3?pg/mL, p?d?=?0.80) suggesting higher IL-6 levels of post-hypoxia. F2-IsoP was significantly lower 1?h post-exercise in both the hypoxic (p?=?.005) and sea-level (p?=?.002) conditions, with no differences between trials. While hypoxia can impact on exercise intensity and may result in greater post-exercise inflammation, it appears to have little effect on oxidative stress. These results indicate that team sport organisations with ready access to hypoxic training facilities could confidently administer RSH without significantly increasing the post-exercise inflammatory or oxidative stress response.  相似文献   

2.
This study investigated protein kinase activation and gene expression of angiogenic factors in response to low-load resistance exercise with or without blood flow restriction (BFR). In a repeated measures cross-over design, six males performed four sets of bilateral knee extension exercise at 20% 1RM (reps per set?=?30:15:15:continued to fatigue) with BFR (110?mmHg) and without (CON). Muscle biopsies were obtained from the vastus lateralis before, 2 and 4?h post-exercise. mRNA expression was determined using real-time RT–PCR. Protein phosphorylation/expression was determined using Western blot. p38MAPK phosphorylation was greater (p?=?0.05) at 2?h following BFR (1.3?±?0.8) compared to CON (0.4?±?0.3). AMPK phosphorylation remained unchanged. PGC-1α mRNA expression increased at 2?h (5.9?±?1.3 vs. 2.1?±?0.8; p?=?0.03) and 4?h (3.2?±?0.8 vs. 1.5?±?0.4; p?=?0.03) following BFR exercise with no change in CON. PGC-1α protein expression did not change following either exercise. BFR exercise enhanced mRNA expression of vascular endothelial growth factor (VEGF) at 2?h (5.2?±?2.8 vs 1.7?±?1.1; p?=?.02) and 4?h (6.8?±?4.9 vs. 2.5?±?2.7; p?=?.01) compared to CON. mRNA expression of VEGF-R2 and hypoxia-inducible factor 1α increased following BFR exercise but only eNOS were enhanced relative to CON. Matrix metalloproteinase-9 mRNA expression was not altered in response to either exercise. Acute low-load resistance exercise with BFR provides a targeted angiogenic response potentially mediated through enhanced ischaemic and shear stress stimuli.  相似文献   

3.
Fatigue represents a reduction in the capability of muscle to generate force. The aim of the present study was to establish the effects of exercise that simulates the work rate of competitive soccer players on the strength of the knee extensors and knee flexors. Thirteen amateur soccer players (age 23.3±3.9 years, height 1.78±0.05?m, body mass 74.8±3.6?kg; mean±s) were tested during the 2000–2001 soccer season. Muscle strength of the quadriceps and hamstrings was measured on an isokinetic dynamometer. A 90?min soccer-specific intermittent exercise protocol, incorporating a 15?min half-time intermission, was developed to provide fatiguing exercise corresponding in work rate to a game of soccer. The exercise protocol, performed on a programmable motorized treadmill, consisted of the different intensities observed during soccer match-play (e.g. walking, jogging, running, sprinting). Muscle strength was assessed before exercise, at half-time and immediately after exercise. A repeated-measures analysis of variance showed significant reductions (P?<0.001) in peak torque for both the quadriceps and hamstrings at all angular velocities (concentric: 1.05, 2.09, 5.23 rad?·?s?1; eccentric: 2.09 rad?·?s?1). The peak torque of the knee extensors (KE) and knee flexors (KF) was greater before exercise [KE: 232±37, 182±34, 129±27, 219±41?N?·?m at 1.05, 2.09 and 5.23 rad?·?s?1 (concentric) and 2.09 rad?·?s?1 (eccentric), respectively; KF: 126±20, 112±19, 101±16, 137±23?N?·?m] than at half-time (KE: 209±45, 177±35, 125±36, 214±43?N?·?m; KF: 114±31, 102±20, 92±15, 125±25?N?·?m) and greater at half-time than after exercise (KE: 196±43, 167±35, 118±24, 204±43?N?·?m; KF: 104±25, 95±21, 87±13, 114±27?N?·?m). For the hamstrings?:?quadriceps ratio, significant changes were found (P?<0.05) for both legs, the ratio being greater before than after exercise. For fast?:?slow speed and left?:?right ratios, no significant changes were found. We conclude that there is a progressive reduction in muscle strength that applies across a range of functional characteristics during exercise that mimics the work rate in soccer.  相似文献   

4.
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5.
The aim of this study was to examine neuromuscular variables contributing to differences in force loss after participants were exposed to the same relative bout of eccentric exercise. Thirty-six males performed 50 maximal eccentric contractions of the elbow flexors and were stratified into high responders (n?=?10) and low responders (n?=?10) based on force loss 36 h after exercise. Maximal voluntary isometric contractions (MVCs) and electromyography (EMG) were measured at baseline and 36 h after exercise. During eccentric exercise, mean peak torque, mean end-range torque from the final 25% of each trial and total angular impulse were computed over 25 contractions in each of two bouts. The slope of the change in these values for each 25 eccentric contractions was calculated for each participant using linear regression. At baseline, MVC was not different between groups (low responders: 97.0?±?9.6 N?·?m; high responders: 82.7?±?6.4 N?·?m; P?=?0.08). High responders demonstrated a 68% (range 62-78%) reduction in MVC and low responders a 39% (29-48%) reduction after exercise. Peak torque, end-range torque and total angular impulse were 13%, 40% and 33% higher, respectively, in the low than in the high responders (peak torque: P?=?0.0002; end-range torque: P?<?0.0001; total angular impulse: P?<?0.001). The rate of decline in peak torque slope was greater in high than in low responders (P?=?0.044). In conclusion, lower peak torque, end-range torque and total angular impulse during eccentric contractions and a greater peak torque slope may identify high responders to eccentric exercise.  相似文献   

6.
Myokines may play a role in the health benefits of regular physical activity. Secreted protein acidic rich in cysteine (SPARC) is a pleiotropic myokine that has been shown to be released into the bloodstream by skeletal muscle in response to aerobic exercise. As there is evidence suggesting that SPARC release may be linked to glycogen breakdown and activation of 5’ adenosine monophosphate-activated protein kinase, we hypothesised that brief supramaximal exercise may also be associated with increased serum SPARC levels. In the present study, 10 participants (3 women; mean?±?SD age: 21?±?3 y, body mass index (BMI): 22?±?3?kg?m?2, and V˙O2max: 39?±?6?mL?kg?1?min?1) performed an acute bout of supramaximal cycle exercise (20-s Wingate sprint against 7.5% of body mass, with a 1-min warm-up and a 3-min cool-down consisting of unloaded cycling). Serum SPARC levels were determined pre-exercise as well as 0, 15, and 60?min post-exercise and corrected for plasma volume change. To determine whether regular exercise affected the acute SPARC response, participants repeated the acute exercise protocol three times per week for four weeks, and serum SPARC response to supramaximal exercise was reassessed after this period. Acute supramaximal exercise significantly decreased plasma volume (?10%; p?<?.001), but was not associated with a significant change in serum SPARC levels at either the pre-training or post-training testing sessions. In conclusion, in contrast to aerobic exercise, a single brief supramaximal cycle sprint is not associated with an increase in serum SPARC levels, suggesting that SPARC release is not related to skeletal muscle glycogen breakdown.  相似文献   

7.
The protective action of remote ischaemic preconditioning (RIPC) has been demonstrated in the context of surgical interventions in cardiology. Application of RIPC to sports performance has been proposed, but its effect on the electrocardiogram (ECG) during exercise remains unknown. This exploratory study aims to measure the changes in ventricular repolarization observed during exercise following RIPC in healthy subjects. In an experimental randomized crossover study, 17 subjects underwent two bouts of constant load exercise tests at 75% and 115% of gas exchange threshold (GET). Prior to exercise, they were allocated to either control or RIPC intervention with four cycles of 5?min of ischaemia followed by 5?min of reperfusion. ECG was continuously recorded during the protocol. QT and RR intervals were measured every 30?s (on an average tracing of the preceding 10?s). Although the time course of RR intervals did not differ between the two interventions (p?=?.56 at 75% GET and p?=?.74 at 115% GET), a significant shortening of QT intervals (measured from Q onset to T end) was observed during exercise (mean?±?standard deviation of RIPC vs. control: ?32?±?19?ms at 75% GET (p?p?p?p?相似文献   

8.
We tested the hypothesis that backward downhill walking (eccentric component) impairs both voluntary activation and muscle contractile properties in the plantar flexors and delays recovery as compared to a gradient and distance-matched uphill walk. Fourteen males performed two 30-min walking exercises (velocity: 1?m/?s; grade: 25%; load: 12% of body weight), one downhill (DW) and one uphill (UP), in a counterbalanced order, separated by 6?weeks. Neuromuscular test sessions were performed before, after, 24-, 48- and 72-h post-exercise, including motor nerve stimulations during brief (5?s) and sustained (1?min) maximal isometric voluntary contractions of the plantar flexors. DW (?18.1?±?11.1%, P?P?=.15), decreased torque production during brief contractions for at least three days post-exercise (P?P?P?=?.024) and DW (?25.6?±?10.3%, P?P?=?.001) was lower in DW than UP. Peak twitch torque and maximum rates of torque development and relaxation were equally reduced after UP and DW (P?P?P?>?.05). Using a direct comparison, the capacity to drive the plantar flexors during sustained contractions remains sub-optimal during the three-day recovery period in response to non-exhaustive, downhill backward walking in reference to an uphill exercise matched for distance covered.  相似文献   

9.
This study examined the effect of hypoxia on growth hormone (GH) release during an acute bout of high-intensity, low-volume resistance exercise. Using a single-blinded, randomised crossover design, 16 resistance-trained males completed two resistance exercise sessions in normobaric hypoxia (HYP; inspiratory oxygen fraction, (FiO2) 0.12, arterial oxygen saturation (SpO2) 82?±?2%) and normoxia (NOR; FiO2 0.21, SpO2 98?±?0%). Each session consisted of five sets of three repetitions of 45° leg press and bench press at 85% of one repetition maximum. Heart rate, SpO2, and electromyographic activity (EMG) of the vastus lateralis muscle were measured throughout the protocol. Serum lactate and GH levels were determined pre-exposure, and at 5, 15, 30 and 60?min post-exercise. Differences in mean and integrated EMG between HYP and NOR treatments were unclear. However, there was an important increase in the peak levels and area under the curve of both lactate (HYP 5.8?±?1.8 v NOR 3.9?±?1.1?mmol.L?1 and HYP 138.7?±?33.1 v NOR 105.8?±?20.8?min.mmol.L?1) and GH (HYP 4.4?±?3.1 v NOR 2.1?±?2.5?ng.mL?1 and HYP 117.7?±?86.9 v NOR 72.9?±?85.3?min.ng.mL?1) in response to HYP. These results suggest that performing high-intensity resistance exercise in a hypoxic environment may provide a beneficial endocrine response without compromising the neuromuscular activation required for maximal strength development.  相似文献   

10.
There is a paucity of research on devices suitable for home-based isometric exercise. Our aim was to compare cardiovascular responses to isometric exercise using novel and established methods. Ten individuals (age 34.0?±?8.5 years, mass 68.2?±?10.4?kg, height 1.72?±?0.09?m; mean?±?s) performed three different isometric exercise protocols with 48?h between each. Each protocol involved four repeated exercise bouts of 2?min at 30% maximum voluntary contraction force using alternate legs (transducer), alternate arms (transducer), or alternate arms (novel device). Systolic blood pressure, diastolic blood pressure, mean arterial blood pressure and heart rate were measured every 30?s. The highest (peak) values during each 2?min bout of exercise were recorded (peak systolic blood pressure, peak diastolic blood pressure, peak mean arterial blood pressure and peak heart rate). At the end of each 2?min exercise bout, the participants rated their perceived discomfort using Borg's CR-10 scale. There was a statistically significant difference in peak systolic blood pressure between isometric arm flexion using the force transducer and the novel device [158.1?±?10.8 vs. 149.1?±?13.9?mmHg (mean?±?s); P = 0.02]. Further analysis showed that peak systolic blood pressure was on average 9?mmHg higher using the force transducer with limits of agreement of –?15.97 to 33.97?mmHg. Analysis of the peak diastolic blood pressure, peak mean arterial blood pressure, peak heart rate and CR-10 data revealed no statistically significant differences between the three protocols. These results suggest that this novel, home-based method elicited similar cardiovascular responses during isometric exercise to those of established laboratory-based methods. However, the lower peak systolic blood pressure using the modified scales warrants further investigation before this method is used widely in the home.  相似文献   

11.
It has previously been shown that females incur less muscle damage than males after strenuous exercise, but limited data are available for humans. To determine possible differences between the sexes in humans, the response to high-force eccentric exercise was examined in a large sample of women (n = 83) and men (n = 82). The participants performed a bout of eccentric exercise of the elbow flexors consisting of 70 maximal repetitions. Isometric strength, resting elbow angle and muscle soreness were measured before, immediately after (except soreness) and then daily for 7 days after exercise. There was a significant loss in strength among both groups (69% for women and 63% for men) (P?0.01) immediately after exercise; at 168 h post-exercise, women still had a 27% strength loss and men had a 24% strength loss. No significant difference in strength loss or recovery rate was found between men and women. Soreness reached peak values 32-48 h post-exercise (P?0.01), with no significant difference between men and women. Range of motion decreased significantly until 3 days after exercise (14.6° or 0.255 rad loss for women; 12.2° or 0.213 rad loss for men) (P?0.01); at 168 h post-exercise, the women and men still showed a loss of 4.8° (0.084 rad) and 4.0° (0.07 rad), respectively. There was a significant interaction of sex x time (P?0.01); a post-hoc test indicated that the women experienced a greater loss in range of motion at 72 h than men and this difference was maintained to 168 h post-exercise (P?0.01). Thus, our results do not support the contention that women have a lower response to eccentric exercise than men.  相似文献   

12.
Abstract

The purpose of this study was to examine the effect of fatiguing exercise on sex-related differences in the function of hamstring and quadriceps muscles at several angular velocities and joint angles. Physically active participants (50 male: 28.7?±?4.5y, 1.82?±?0.07 m, 82.3?±?6.87?kg; 50 female: 27.0?±?5.8y, 1.61?±?0.08 m, 68.75?±?9.24?kg) carried out an isokinetic assessment to determine concentric and eccentric torques during knee extension and flexion actions at three different angular velocities (60/180/300°/s). The H/QFUNCT was calculated using peak torque (PT) values at 3 different joint-angle-specific (15°, 30° and 45° of knee flexion). A repeated measures analysis of variance (ANOVA) was used to compare within group results. Between group comparisons of sex-related differences were assessed by independent T-tests. Fatiguing exercise in males resulted in a decrease in H/QFUNCT ratios for each angle of knee flexion at both 60°/s and 300°/s angular velocities (p?<?0.05). In females, significant decreases in H/QFUNCT ratios were observed following fatiguing exercise for each angle of knee flexion and angular velocity (p?<?0.01). Significant differences in H/QFUNCT ratios following fatiguing exercise were evident between males and females at each joint angle and angular velocity (p?<?0.01). These findings indicate sex related differences in H/QFUNCT ratios following fatiguing exercise. Females have greater reductions in torque and H/QFUNCT ratios following fatigue than their male counterparts. This potentially exposes females to higher risks of injury, particularly when fatigued. Practitioners should attend to the imbalance in fatigue resistance of hamstring and quadriceps function, particularly in female athletes.  相似文献   

13.
We sought to determine the sex-specific effects of an acute bout of free-weight resistance exercise (RE) on pulse wave reflection (aortic blood pressures, augmentation index (AIx), AIx at 75?bpm (AIx@75), augmentation pressure (AP), time of the reflected wave (Tr), subendocardial viability ratio (SEVR)), and aortic arterial stiffness in resistance-trained individuals. Resistance-trained men (n?=?14) and women (n?=?12) volunteered to participate in the study. Measurements were taken in the supine position at rest, and 10 minutes after 3 sets of 10 repetitions at 75% 1-repetition maximum on the squat, bench press, and deadlift. A 2?×?2?×?2 ANOVA was used to analyse the effects of sex (men, women) across condition (RE, control) and time (rest, recovery). There were no differences between sexes across conditions and time. There was no effect of the RE on brachial or aortic blood pressures. There were significant condition?×?time interactions for AIx (rest: 12.1?±?7.9%; recovery: 19.9?±?10.5%, p?=?.003), AIx@75 (rest: 5.3?±?7.9%; recovery: 24.5?±?14.3%, p?=?.0001), AP (rest: 4.9?±?2.8?mmHg; recovery: 8.3?±?6.0?mmHg, p?=?.004), and aortic arterial stiffness (rest: 5.3?±?0.6?ms; recovery: 5.9?±?0.7?ms, p?=?.02) with significant increases during recovery from the acute RE. There was also a significant condition?×?time for time of the reflected wave (rest: 150?±?7?ms; recovery: 147?±?9?ms, p?=?.02) and SEVR (rest: 147?±?17%; recovery: 83?±?24%, p?=?.0001) such that they were reduced during recovery from the acute RE compared to the control. These data suggest that an acute bout of RE increases AIx, AIx@75, and aortic arterial stiffness similarly between men and women without significantly altering aortic blood pressures.  相似文献   

14.
Runners often experience delayed onset muscle soreness (DOMS), especially of the knee extensors, following prolonged running. Sagittal knee joint biomechanics are altered in the presence of knee extensor DOMS but it is unclear how muscle soreness affects lower limb biomechanics in other planes of motion. The purpose of this study was to assess the effects of knee extensor DOMS on three-dimensional (3D) lower limb biomechanics during running. Thirty-three healthy men (25.8?±?6.8 years; 84.1?±?9.2?kg; 1.77?±?0.07?m) completed an isolated eccentric knee extensor damaging protocol to elicit DOMS. Biomechanics of over-ground running at a set speed of 3.35?m?s?1±5% were measured before eccentric exercise (baseline) and, 24?h and 48?h following exercise in the presence of knee extensor DOMS. Knee flexion ROM was reduced at 48?h (P?=?0.01; d?=?0.26), and peak knee extensor moment was reduced at 24?h (P?=?0.001; d?=?0.49) and 48?h (P?<?0.001; d?=?0.68) compared to baseline. Frontal and transverse plane biomechanics were unaffected by the presence of DOMS (P?>?0.05). Peak positive ankle and knee joint powers and, peak negative knee joint power were all reduced from baseline to 24?h and 48?h (P?<?0.05). These findings suggest that knee extensor DOMS greatly influences sagittal knee joint angular kinetics and, reduces sagittal power production at the ankle joint. However, knee extensor DOMS does not affect frontal and transverse plane lower limb joint biomechanics during running.  相似文献   

15.
The acute influence of chain-loaded variable resistance exercise on subsequent free-weight one-repetition maximum (1-RM) back squat performance was examined in 16 recreationally active men. The participants performed either a free-weight resistance (FWR) or chain-loaded resistance (CLR) back squat warm-up at 85% 1-RM on two separate occasions. After a 5-min rest, the participants attempted a free-weight 1-RM back squat; if successful, subsequent 5% load additions were made until participants failed to complete the lift. During the 1-RM trials, 3D knee joint kinematics and knee extensor and flexor electromyograms (EMG) were recorded simultaneously. Significantly greater 1-RM (6.2?±?5.0%; p?p?p?>?.05) was found in concentric EMG, eccentric or concentric knee angular velocity, or peak knee flexion angle. Performing a CLR warm-up enhanced subsequent free-weight 1-RM performance without changes in knee flexion angle or eccentric and concentric knee angular velocities; thus a real 1-RM increase was achieved as the mechanics of the lift were not altered. These results are indicative of a potentiating effect of CLR in a warm-up, which may benefit athletes in tasks where high-level strength is required.  相似文献   

16.
ABSTRACT

This study examined changes in enjoyment, affective valence, and rating of perceived exertion (RPE) in obese women performing two regimes of high intensity interval training (HIIT) differing in structure and volume. Nineteen obese and inactive women (age and body mass index?=?37.5?±?10.5?yr and 39.0?±?4.3?kg/m2) were randomized to 6?wk of traditional (TRAD, n?=?10) or periodized interval training (PER, n?=?9) which was performed on a cycle ergometer during which structure changed weekly. Two supervised sessions per week were performed in a lab, and one session per week was performed unsupervised. During every lab-based session, perceptual responses including enjoyment, affective valence, and RPE were acquired. Data showed a groupXtraining interaction for enjoyment (p?=?0.02) which was lower by 10–25 units during PER versus TRAD. In addition, there was a groupXtimeXtraining interaction for RPE (p?=?0.01). RPE did not change in response to TRAD yet varied during PER, with lower RPE values exhibited during brief supramaximal bouts (6.3?±?0.9) compared to longer intervals (7.3?±?1.2). Both regimes showed reductions in affective valence during training, with the lowest values equal to 1.5?±?1.6 in TRAD and ?0.2?±?1.6 in PER. Compared to TRAD, more aversive responses were shown in PER throughout training by 0.4–2.0 units. Data show lower enjoyment and more aversive responses to higher-volume bouts of interval training, which suggests that shorter bouts may be perceived more favourably by obese women.  相似文献   

17.
Chronic exertional compartment syndrome (CECS) is characterized by pain occurring during physical activity. As clinical examination is not sufficient to diagnose it, intracompartmental pressure (ICP) measure is used for CECS confirmation. Numerous clinical signs are reported but their diagnosis predictive ability has never been studied. We aimed to determine if the 12 classically reported clinical signs are predictive of CECS. We performed a single-centre retrospective cohort study on patients referred for CECS suspicion. Patients were asked to run on a treadmill. When pain occurred, post-exercise ICP was performed. We diagnosed CECS if the ICP was ≥30?mmHg and used a logistic regression to calculate the predictive value of clinical signs. One hundred twenty-five patients were evaluated. Ninety-six had CECS and 29 did not, according to the ICP 30?mmHg cut-off. Anterior and lateral compartments were the most frequently affected. After exercise, mean ICP was 58.6?mmHg?±?20.5 in the group with CECS versus 20.9?mmHg?±?4 in the group without (p?p?p?相似文献   

18.
This investigation examined effects of two exercise modes (barbell, BB; bodyweight suspension, BWS) on muscle activation, resistance load, and fatigue. During session one, nine resistance-trained males completed an elbow flexion one-repetition maximum (1RM). During sessions two and three, subjects completed standing biceps curls to fatigue at 70% 1RM utilizing a randomized exercise mode. Surface electromyography (sEMG) recorded muscle activation of the biceps brachii, triceps brachii, anterior deltoid, posterior deltoid, rectus abdominis, and erector spinae. BWS resistance load was measured using a force transducer. Standing maximal voluntary isometric contractions of the elbow flexors recorded at 90° were used to determine the isometric force decrement and rate of fatigue (ROF) during exercise. sEMG and resistance load data were divided into 25% contraction duration bins throughout the concentric phase. BWS resulted in a 67.7?±?7.4% decline in resistance load throughout the concentric phase (p?≤?0.05). As a result, BB elicited higher mean resistance loads (31.4?±?4.0?kg) and biceps brachii sEMG (84.7?±?27.8% maximal voluntary isometric contractions, MVIC) compared with BWS (20.4?±?3.4?kg, 63.4?±?21.6% MVIC). No difference in rectus abdominis or erector spinae sEMG was detected between exercise modes. Isometric force decrement was greater during BWS (?21.7?±?7.0?kg) compared with BB (?14.9?±?4.7?kg); however, BB (?3.0?±?0.8?kg/set) resulted in a steeper decline in ROF compared with BWS (?1.7?±?0.6?kg/set). The variable resistance loading and greater isometric force decrement observed suggest that select BWS exercises may resemble variable resistance exercise more than previously considered.  相似文献   

19.
ABSTRACT

Interval exercise training is increasingly recommended to improve health and fitness; however, it is not known if cardiovascular risk is different from continuous exercise protocols. This systematic review with meta-analyses assessed the effect of a single bout of interval exercise on cardiovascular responses that indicate risk of cardiac fibrillation and infarction compared to continuous exercise. Electronic databases Medline, CINAHL, Embase, Scopus and Cochrane were searched. Key inclusion criteria were: (1) intervals of the same intensity and duration followed by a recovery period and (2) reporting at least one of blood pressure, heart rate variability, arterial stiffness or function. Cochrane Risk of Bias tool and GRADE approach were used. Meta-analyses found that systolic blood pressure responses to interval exercise did not differ from responses to continuous exercise immediately (MD 8 mmHg [95% CI ?32, 47], p = 0.71) or at 60 min following exercise (MD 0 mmHg [95% CI ?2, 1], p = 0.79). However, reductions in diastolic blood pressure and flow-mediated dilation with interval exercise were observed 10–15 min post-exercise. The available evidence indicates that interval exercise does not convey higher cardiovascular risk than continuous exercise. Further investigation is required to establish the safety of interval exercise for clinical populations.  相似文献   

20.
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