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Sharmila Upadhya Subramanya Upadhya K. S. Prabhu 《Indian journal of clinical biochemistry : IJCB》2002,17(1):20-24
The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer.
Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All
the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid
levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001, P=0.03).
Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared
to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia,
as serum ceruloplasmin (an acute phase reactant) is also increased in these patients. 相似文献
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Garg Anuj A Sharmila Kumar Pramod Madhukar Mani Loyola-Gonz&#;lez Octavio Kumar Manoj 《Education and Information Technologies》2022,27(4):4793-4815
Education and Information Technologies - Nowadays, internet technology plays a vital role in all the fields of our daily lives ranging from the world economy, professional careers, higher... 相似文献
13.
G. Sharmila Banu G. Kumar A. G. Murugesan 《Indian journal of clinical biochemistry : IJCB》2009,24(4):414-418
The aim of this study was to investigate the ethanolic leaf extract of Trianthema portulacastrum L. (Family: Aizoaceae) on
aflatoxin induced hepatic damage in rats. Aflatoxin intoxication in rats significantly (p < 0.001) elevated the levels of
serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), alkaline phosphatase (ALP),
and total bilirubin, which indicated acute hepatocellular damage and biliary obstruction. Ethanolic leaf extract of T. portulacastrum
showed dose dependent decrease in the levels of SGPT, SGOT, ALP and total bilirubin. Minimum effective dose of extract was
found to be 100 mg/kg body weight. Results obtained from histopathological studies also supported hepatoprotective activity
against aflatoxin-induced hepatotoxicity. Thus the study demonstrates that T. portulacastrum possess antihepatotoxic effect
against aflatoxin. 相似文献
14.
Bhaskar S Veena Sharmila Upadhya Satish Kumar Adiga Kumar N Pratap 《Indian journal of clinical biochemistry : IJCB》2008,23(2):186-190
The objective of the study was to estimate the serum concentrations of oxidative stress markers-lipid hydroperoxide (MDA-Malondialdehyde),
lactate dehydrogenase (LDH), nitrite; and ferric reducing antioxidant power (FRAP) — a measure of total antioxidant capacity
in serum. Serum nitrite levels were high in fertile women than in infertile women (p<0.001), whereas MDA was high in infertile
women than in fertile group (p<0.018). On classifying the entire group of women with infertility based on the etiology, serum
MDA and LDH levels were higher in women with infertility due to unexplained factor than in women with other causes contributing
to infertility compared to controls (p<0.001, p<0.02). A positive correlation among serum prolactin and nitrite suggested
that hyperprolactinemia could contribute to infertility by inducing oxidative damage. Serum FRAP levels showed no significant
difference in the groups studied. Lipid peroxidation was high in women with unexplained infertility which may be due to hyperprolactinemia. 相似文献
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Courses: Any communication course requiring a literature review, including, but is not limited to, Communication Research Methods and Communication Theory.
Objectives: After completing this activity, students should be able to write better literature reviews by (1) locating a range of resources; (2) identifying a variety of relevant information (that directly relates to the question at hand) from within a popular social medium; (3) identifying relevant information from scholarly works and making informed judgments about what information should be used or discarded; and (4) synthesizing information from disparate sources, drawing appropriate inferences and conclusions from the available research to communicate a point clearly. 相似文献
17.
Biochemical activity of selenium and glutathione on country made liquor (CML) induced hepatic damage in rats 总被引：1，自引：0，他引：1
G. Kumar G. Sharmila Banu M. Rajasekara Pandian 《Indian journal of clinical biochemistry : IJCB》2007,22(1):105-108
The serum and hepatic enzymes of rats were studied after exposed to country made liquor (CML) along with two chelating agents
(glutathione and Selenium). There was a significant increase in several serum enzyme levels (viz., aspartate transaminase,
alanine transaminase, alkaline phosphatase, sorbitol dehydrogenase, glutamate dehydrogenase, bilirubin) and decrease in various
hepatic enzymes (Succinic dehydrogenase, Glucose 6-phosphatase, 5'Nucleotiease, Acid phosphatase, Acid ribonuclease, Cytochrome
P-450) due to repeated administration of CML (2ml/100g of body weight). Results of this study revealed that the GSH and Se
could give a significant protective action in serum and hepatic enzymes of CML exposed rats. 相似文献