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21.
Rashmi Raghuvanshi Aiki Kaul Pushpa Bhakuni Aparna Mishra M. K. Misra 《Indian journal of clinical biochemistry : IJCB》2007,22(2):90-92
In the present communication, we report remarkably elevated levels of xanthine oxidase activity in the blood of the patients
with myocardial infarction when compared to age and sex matched healthy persons. Highly significant increase of malondialdehyde,
serving as an index of lipid peroxidation and thus free radical mediated damage, has also been found in the patients. We propose
the measurement of the blood levels of xanthine oxidase, a very simple, reliable and less time consuming method as an indicator
of myocardial infarction. 相似文献
22.
Jaleel CA Gopi R Manivannan P Kishorekumar A Gomathinayagam M Panneerselvam R 《Journal of Zhejiang University. Science. B》2007,8(4):283-288
The ability of triadimefon(TDM),a triazolic fungicide,to alter the biochemical constituents and thereby minimizing the days required for sprouting in white yam(Dioscorea rotundata Poir.) tubers during storage under(30±2) °C in the dark,was studied.TDM at 20 mg/L was given to tubers by dipping the tubers in treatment solution containing 20 mg/L TDM on 10,25 and 40 d after storage(DAS).Starch,sugars,protein,amino acid contents as well as protease and α-amylase activities were estimated on 15,30 and 45 DAS from two physiological regions viz.,apical and basal regions of the tubers.In normal conditions(control) sprouting occurred on 70 to 80 DAS.The starch content decreased,while protein,amino acid,sugar contents and protease and α-amylase activities were increased due to TDM treatment and led to early sprouting. 相似文献
23.
Moushumi Lodh Binita Goswami Rajni Dawar Mahajan Dipankar Sen Nirmal Jajodia Abhishek Roy 《Indian journal of clinical biochemistry : IJCB》2015,30(2):174-179
Low back pain is very disabling and dispiriting because of the physical impediment it causes and its psychological effects. Innumerable factors have been implicated in its etiology. In spite of improvements in diagnostic modalities, a considerable number of such cases fall in the ambiguous zone of unknown etiology or ‘idiopathic.’Early diagnosis of low back pain will allow effective prevention and treatment to be offered. This study was conducted to assess the contribution of vitamin D levels and other biochemical factors to chronic low back pain in such cases. All patients attending the orthopedics OPD for low back pain in whom a precise anatomical cause could not be localized, were prospectively enrolled in this study. We measured serum levels of glucose, calcium, phosphorus, uric acid, rheumatoid factor, C reactive protein, alkaline phosphatase, total protein, albumin and 25 (OH) D concentrations in 200 cases and 200 control samples. The patients showed significantly lower vitamin D levels compared to controls with p value < 0.0001. The maximum number of low back pain patients were in the age group of 31–50 years (42 %).The average BMI was 23.27 ± 5.17 kg/sq m, 73 % of total patient population were females and 27 % were known case of type 2 diabetes mellitus. Calcium, alkaline phosphatase, was positively correlated with vitamin D and glucose showed a negative correlation with vitamin D in the patient population. The problem of low back pain provides a challenge to health care providers. The problem in developing countries is compounded by ignorance to report for early treatment and occupational compulsions in rural areas and sedentary lifestyle in urban youth. The authors strongly recommend early frequent screening for vitamin D along with glucose, protein, albumin, calcium, phosphorus, CRP as part of general health checkup for non-specific body pain, especially low back pain. 相似文献
24.
M. Mastan U. V. Prasad P. R. Parthasarathy 《Indian journal of clinical biochemistry : IJCB》2007,22(1):122-127
Bacopa monniera, a medicinal plant distributed throughout India. Cytosine arabinoside (1-β-arabinofuranosylcytosine; Ara-C)
is the most important antimetabolite chemotherapeutic drug used for acute leukemia. In this study we examined the chemoprotective
property of an ethanolic extract of Bacopa monniera on biochemical changes in chick embryo. CA caused biochemical changes
in a concentration and time dependent manner in amniotic fluid, liver and heart tissues. Ethanolic extract of BM given to
chick embryo at doses of 2, 4, 6 mg per egg. There is significant decrease in biochemical levels of glucose, protein, urea,
uric acid, creatinine and inorganic phosphorus. Enzymatic activities of alkaline phosphatase, lactate dehydrogenase, serum
glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase and malatedehydrogenase were also decreased with
dose dependent manner in amniotic fluid, liver and heart tissues. 相似文献
25.
K. M. Elizabeth 《Indian journal of clinical biochemistry : IJCB》2005,20(2):150-153
The antimicrobial activity of crude and methanol extract ofTerminalia bellerica dry fruit was tested by disc diffusion method, against 9 human microbial pathogens. Crude aqueous extract of dry fruit at
4 mg concentration showed zone of inhibition ranging from 15.5–28.0 mm.S. aureus was found to be highly susceptible forming highest zone of inhibition, suggesting thatT. bellerica was strongly inhibitory towards this organism. These pathogens were highly sensitive to the methanol extract forming 14.0
to 30.0 mm zone of inhibition suggesting that the methanol extract ofT. bellerica was more effective than crude extract against most of the microbes tested exceptE. coli (enteropathogen) andP. aeruginosa. The minimal inhibitory concentrations (MICs) of crude and methanol extracts were determined by broth dilution technique
which ranged from 300 to >2400 μg/ml and 250 μg to >2000 μg/ml respectively, indicating thatT. bellerica was highly effective againstS. aureus with lower MIC values. There were some biochemical alterations induced byT. bellerica. These results indicate thatT. bellerica dry fruit possesses potential broad spectrum antimicrobial activity. 相似文献
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27.
研究一类生化反应的数学模型,利用微分方程定性理论,完整地解决了该系统极限环的存在性、唯一性和不存在性. 相似文献
28.
青春期女孩雌激素的分泌在初潮时期迅速升高,而反映骨代谢变化情况的生化标志物(bone biochemical marker)在血液中的水平明显下降,这表明雌激素的水平与骨代谢生化标志物之间存在着相关性、骨代谢生化标志物的下降标志着长骨两端骺软骨的生长骨板逐渐愈合,长骨内外表面骨组织合成减少,骨密度、骨松质的重建减慢,雌激素导致的这些变化主要通过促进生长骨板中的软骨细胞及骨密质和骨松质中破骨细胞凋亡来实现。在青春早期桡骨骨折的发生率十分的高,这可能与骨代谢生化标志物水平增高有关,另外,女孩初潮时间推迟会导致中老年时期骨折的危险因素增高,与同龄人相比骨密度下降。这都表明初潮时期女孩的雌激素分泌对骨骼的代谢有着重要的调节作用。 相似文献
29.
Fleming JJ Janardhan HP Jose A Selvakumar R 《Indian journal of clinical biochemistry : IJCB》2011,26(1):32-40
In the present study, the cause of suspected false-positive (anomalous) values for CK-MB activity, in Indian patients investigated
for ACS. Total serum CK and CK-MB activity, serum Troponin I were measured and CK-MB as a percentage of the total CK activity
(%CK-MB) calculated. CK-MB was also estimated using densitometry and CK-MB mass assay. Anomalous specimens were tested for
the presence of CK isoenzymes. In 22 healthy subjects, 11 male and female, the %CK-MB ranged from 3.6 to 30.2. In 11 male
patients, with proven ACS, the %CK-MB was from 4.0 to 17.5. The cut off for anomalous CK-MB activity values was set as >33.0%.
In 35 patients with anomalies, total CK values ranged from 39 to 231 U/L, CK-MB from 30 to 161 U/L. Investigation of CK isoenzymes,
showed 10 patients had a CK-BB band, 14 an intermediate band between CK-MM and CK-MB (macro-CK type 1), 7 had a cathodal band
(macro-CK type 2), and 3 had a band intermediate between CK-MB and CK-BB. This later band does not seem to have been previously
reported. Against the CK-MB mass assay, the activity assay showed no correlation, in 43 patients (19 M, 24 F), Pearson coefficient
(R2) was 0.006. The CK-MB immunoinhibition assay is better described as measuring “non-CK-MM activity.” A %CK-MB activity >6%
as a marker of ACS is not valid in our patient population. Laboratories should not use only CK-MB activity as a biochemical
marker of ACS. 相似文献
30.