排序方式： 共有8条查询结果，搜索用时 171 毫秒
1
1.
2008年冬天,一个雪夜,噩耗从天而降:父亲的爷爷、我的太爷爷去世了,远在外地的父亲听到这个消息,连夜赶了回来。此时,寒风凛冽,大雪纷飞。曾听父亲说过,小时候,爷爷对他特别好,什么好东西都留着给他。门外喇叭声不断,父亲骑着电动车到了家,奶奶和我站在厨房门口望着他。他劈头一句就是:爷爷真走了吗? 相似文献
3.
这是一堂初三的作文研究性教学课,目的在于让学生学会将主观感受注入所描摹的事物中。笔者希望通过让学生观察一种比较陌生、但近年来颇引人关注的花———"彼岸花"的外形,再结合此花的传说,引导学生描摹出这种花在典型环境下的"神韵",从而举一反三,让作文中的描写为叙事服务,不脱离叙事而突兀地存在,同时更具典型性,避免流俗、人云亦云。考虑到课堂教学的紧凑性,加之本课时中拓展环节难度较大等因素,课前我安排学生仔细观察彼岸花的图片,并要求每人写一句话进行描写,至少使用一种修辞手法。 相似文献
4.
6.
Purpose: To investigate the relationship between expression of cell cycle-related protein cyclin D1, p27kipl and the pathogenesis of bronchioloalveolar carcinoma (BAC) and the value of prediction of prognosis. Methods: Cyclin D 1 and p27kip 1 protein were detected by immunohistochemical En Vision method in 43 BACs. Results: The positivity of cyclin D 1 in BAC was 65.1% (28/43), which was significantly higher than that in normal pulmonary tissue (0/13), P＜0.01. No statistically significant association was found between cyclin D1 expression data and sex, age, tobacco-use history, histologic subtype (mucinous vs nonmucinous), stromal fibrosis, lymph node metastasis, clinical stage or postoperative survival period (P＞0.05), while cyclin D1 expression was found to be negatively correlated with tumor size (P＜0.05). The positivity of p27kipl in BACs was 51.2% (22/43), significantly lower than that in normal pulmonary tissue (12/13), P＜0.01. p27kipl expression level was not associated with sex, age, tobacco-use history, tumor size or histologic subtype (P＞0.05), but was negatively correlated with stromal fibrosis, lymph node metastasis and clinical stage (P＜0.05); and positively associated with postoperative survival period (P＜0.01). The survival rate of p27kipl positive group was significantly higher than that of p27kipl negative group (P＜0.01). No statistically significant correlation was found between cyclin D 1 and p27kipl expression. Conclusions: Increased cyclin D1 expression and decreased p27kip 1 expression are related to the pathogenesis of BAC;decreased p27kipl expression is associated with metastasis progression; immunodetection ofp27kip 1 is useful for assessment of prognosis. 相似文献
7.
INTRODUCTION Bronchioloalveolar carcinoma (BAC) is a par-ticular subtype of pulmonary adenocarcinoma de-rived from clara cell and type II pneumocyte. BAC cells grow along and within alveolar spaces while the alveolar framework of the lung is preserved. The incidence of BAC appears to be rising recently. The etiology and pathogenesis of this unique neoplastic disease are still unclear; many studies of oncogene and tumor suppressor gene expression include BAC with all adenocarcinoma o… 相似文献
8.
近年来全球天然气需求和价格的不断增长促使欧盟开展天然气市场改革以确保天然气供给安全和相关产业竞争力。但欧盟相关改革指令的执行情况并不尽如人意,从而导致欧盟天然气市场改革进展缓慢,各成员国天然气市场仍处在分割的状况。欧盟天然气市场改革这种差强人意的状况引发了欧盟官方和学术界的各种讨论。本文对各方观点进行分析,揭示了欧盟指令效力的不对称、基建能力不足、监管和处罚措施不力以及贸易联系刚性是阻碍欧盟天然气市场改革的主要障碍,并在此基础上对欧盟天然气市场发展前景进行展望,本文认为欧盟天然气市场的发展进程将会出现以下趋势：①欧盟内部天然气市场发展呈现多层次性的特点;②欧盟天然气基建设施进一步发展,LNG在欧盟天然气市场中地位显著上升;③天然气短期交易发展迅速,长期合同虽减少仍占据重要地位;④欧盟天然气市场定价机制多样化,但石油价格仍然对天然气价格有重大影响。 相似文献
1