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The normal family of linear (time-variant) n-ports is introduced as the most natural extension of ordinary scalar driving-point immittance behaviour. The normality induces a certain symmetry and simplicity which merits due emphasis in future n-port research investigations. As an application of the concept of normality the overdamped-underdamped criterion is extended to n-ports. Also, an interesting problem of maximal power transfer is solved and the absolute energy invariant index calculated. This paper invites attention to the development of circuit synthesis procedures based on the algebraic structure of the normal family.  相似文献   
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Dissipative operators appear in abundance in the study of dynamical systems. In the classical circuit theory they are presented as Positive Real Functions. The coefficients of the Taylor expansion of PRF (driving-point impedance or admittance) must satisfy certain derived inequalities. A method is suggested for obtaining restrictions of the derivative of Positive Real Functions (Dissipative Operators).  相似文献   
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Selection medium is important in sperm isolation for assisted reproductive technologies. Contrary to the naturally occurring human cervical mucus which has a high viscosity, most current practices for motility based sperm selection use a low viscosity medium. In this study, we used a microfluidic device to assess the effects of high viscosity media made with hyaluronic acid (HA) and methyl cellulose (MC) on bovine and human sperm motility and viability (sperm transferred directly from cryoprotectant). The microfluidic penetration test, viability, and motility were compared for sperm swimming in both HA and MC media with about 20cp viscosity (measured at 20 °C). Our resulted indicate that MC medium resulted in a significantly higher number of viable bovine sperm penetrating the medium as compared to HA. Furthermore, MC resulted in the selection of a sperm subpopulation with a 274% increase in sperm viability in comparison to the raw semen, while HA increased viability by only 133%. In addition to viability, bovine sperm motility parameters were significantly higher in the MC medium as compared with HA. Experiments with human sperm swimming in MC indicate that sperm swim slower and straighter at higher viscosities. In conclusion, the results indicate that in a micro-confined environment representative of the in vivo environment, MC is a preferred high viscosity medium to ensure the highest concentration of motile and viable sperm.  相似文献   
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Methods for assaying lysosomal diseases in dried blood samples are very useful today due to its several advantages related to the stability of samples, its transportation, handled and analysis, and its potential use for newborn screening compared to traditional methods in leucocytes samples. For this reason, it is important to validate these assays before being used in routine laboratory. Because of different in biological markers based on ethnicity, we aimed this study to validation a DBS-based fluorometric assay for measurement of α-l-Iduronidase activity for diagnosis of MPS I patients in Iran. DBS samples were collected from 15 MPS I patients and 60 healthy age matched subjects. Diagnostic value, biological variance and α-l-Iduronidase activity were determined. DBS α-l-Iduronidase activity was significantly higher in male subjects than in female group. Using a cut-off level of 1.08 µmol/spot 20 h, sensitivity and specificity were 100 and 98 %. The linearity of test was proved and we showed that within-run and between run precision were 5.6 and 14.66 %. Measurement of α-l-Iduronidase activity in DBS samples is an accurate test for diagnosis of MPS I and because of its rapid shipping and simplicity to keeping, DBS-based enzyme activity could be considered as a useful diagnostic tool in this disease.  相似文献   
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This paper introduces a new way of evaluating instructional strategies by using computers. Two basic theories, instructivism and constructivism, are discussed and critically evaluated in terms of their effectiveness in conceptual learning. Despite the current popularity of constructivism, the radical form of it is criticized in this paper. The advantages and limitations of these two approaches, especially the radical forms of constructivism, are outlined. After borrowing some ideas from other effective conceptual change models, an integrative model for conceptual learning (the Inventive Model) is introduced. Two versions of multimedia physics software are developed by the authors. The first version is based on the Inventive Model and the second version based on a radical constructivist model. The effectiveness of the Inventive Model was compared with the radical constructivist approach and conventional science instruction. Students' log files were analyzed to investigate the nature and the processes of the conceptual change. A conceptual test and a knowledge test were used to compare the groups. The quantitative results showed the superiority of the Inventive Model over the other models in conceptual learning and the superiority of conventional instruction in learning the basic knowledge. The qualitative analysis showed that only the Inventive Model lead to coherent conceptual learning. It was concluded that the process of conceptual change is gradual and continuous. Analysis of students' log files revealed no moments of dramatic change in students' conceptions.  相似文献   
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The main purpose of this study was to assess the effects of doodling on the learning performance of high school female students in Tehran. The design of this research was a pre‐test–post‐test with a control group. A group of 169 junior high school 12–13 year‐old students was chosen for this study. After being taught a section of the Natural Science course, the students were asked to answer questions related to the lessons. After that, their grades were used as the pre‐test scores. The post‐test was carried out after the devised treatment. During ten sessions of the same course and teacher, the students were each given a blank sheet of paper and were asked for doodling if they felt like doing it. After each session, a couple of relevant written questions were asked to evaluate how well students had learned the lessons. The experiment and control group both consisted of 27 randomly selected students; participants in the experiment group were doodlers and those in the control group did not doodle. To evaluate the doodling effect a t‐test analysis was performed. Comparison of the grades showed that the experiment group outperformed the control group significantly.  相似文献   
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