The legacy of Nikola Tesla
The AC system that he helped to usher in     

D P Sen Gupta 《Resonance》2007,12(3):54-69

Alternating Current (AC) is used all over the world today. In India we use AC at 50 Hz (cycles per second) and in USA and Canada at 60 Hz. During the latter part of the 19th century, even during the early part of the 20th century, Direct Current or DC was widely used. Had we continued with DC, electricity would not have been as widely available as it is today and its use would have been cumbersome, costly and severely restricted. We owe it mainly to the Serbian genius Nikola Tesla that electricity has reached almost every nook and corner of most continents.  相似文献   

Interaction of LDL and platelets in ischaemic and ischaemic risk subjects     

Yashika Gupta  V. Mallika  D. K. Srivastava 《Indian journal of clinical biochemistry : IJCB》2005,20(1):87-94

Platelets play a vital role in the progression of atherosclerosis and thrombosis, a major cause of death worldwide. Platelets are activated by many triggers like elevated LDL in blood resulting in aggregation and formation of plaque. The purpose of this study was to investigate the effect of LDL and signal transduction inhibitor on the activation of platelets in Ischaemic risk subjects. Platelets from IHD and hyperlipidemic subjects were hypersensitive to ADP, as higher levels of platelet aggregation were observed in these groups. LDL from IHD hyperlipidemic subjects was more effective in activating platelets from any other group. Ox-LDL was more effective in activating platelets than native-LDL as monitored by level of platelet aggregation induced by PAF and thrombin. Calcium channel blocker, nifedipine and verapamil inhibited platelet aggregation at micromolar level. Protein kinase inhibitor, staurosporine was effective in inhibiting ADP induced aggregation at nanomolar level.  相似文献   

Liquid–Liquid Extraction and Solid Phase Extraction for Urinary Organic Acids: A Comparative Study from a Resource Constraint Setting     

Chandrawati Kumari  Bijo Varughese  Siddarth Ramji  Seema Kapoor 《Indian journal of clinical biochemistry : IJCB》2016,31(4):414-422

Pre analytical process of extraction for accurate detection of organic acids is a crucial step in diagnosis of organic acidemias by GCMS analysis. This process is accomplished either by solid phase extraction (SPE) or by liquid–liquid extraction (LLE). Both extraction procedures are used in different metabolic laboratories all over the world. In this study we compared these two extraction procedures in respect of precision, accuracy, percent recovery of metabolites, number of metabolites isolated, time and cost in a resource constraint setup. We observed that the mean recovery from SPE was 84.1 % and by LLE it was 77.4 % (p value <0.05). Moreover, the average number of metabolites isolated by SPE and LLE was 161.8 ± 18.6 and 140.1 ± 20.4 respectively. The processing cost of LLE was economical. In a cost constraint setting using LLE may be the practical option if used for organic acid analysis.  相似文献   

QTL analysis for some quantitative traits in bread wheat     

Pushpendra KG  Harindra SB  Pawan LK  Neeraj K  Ajay K  Reyazul RM  Amita M  Jitendra K 《Journal of Zhejiang University. Science. B》2007,8(11):807-814

Quantitative trait loci (QTL) analysis was conducted in bread wheat for 14 important traits utilizing data from four different mapping populations involving different approaches of QTL analysis. Analysis for grain protein content (GPC) sug- gested that the major part of genetic variation for this trait is due to environmental interactions. In contrast, pre-harvest sprouting tolerance (PHST) was controlled mainly by main effect QTL (M-QTL) with very little genetic variation due to environmental interactions; a major QTL for PHST was detected on chromosome arm 3AL. For grain weight, one QTL each was detected on chromosome arms 1AS, 2BS and 7AS. QTL for 4 growth related traits taken together detected by different methods ranged from 37 to 40; nine QTL that were detected by single-locus as well as two-locus analyses were all M-QTL. Similarly, single-locus and two-locus QTL analyses for seven yield and yield contributing traits in two populations respectively allowed detection of 25 and 50 QTL by composite interval mapping (CIM), 16 and 25 QTL by multiple-trait composite interval mapping (MCIM) and 38 and 37 QTL by two-locus analyses. These studies should prove useful in QTL cloning and wheat improvement through marker aided selection.  相似文献   

Muscle relaxation therapy in hyperkinesis: is it effective?     

V Bhatara  L E Arnold  T Lorance  D Gupta 《Journal of learning disabilities》1979,12(3):182-186

  相似文献   

Examining the discourse on waste in school education from the standpoint of marginalized communities in Mumbai     

Srivastava  Himanshu  Gupta  Ankush  Raveendran  Aswathy 《Cultural Studies of Science Education》2022,17(2):301-330

Cultural Studies of Science Education - The M(East) ward of Mumbai is home to one of Asia’s largest open landfill sites. Waste, therefore, is a source of livelihood for millions of people...  相似文献   

The perceived impact of external evaluation: the system,organisation and individual levels—Estonian case     

Riin Seema  Maiki Udam  Heli Mattisen  Liia Lauri 《Higher Education》2017,73(1):79-95

The purpose of this article is to provide an overview of how the employees of higher education institutions perceive the impact of external evaluations. The study was conducted using the concurrent mixed method and involved 361 employees from Estonian universities and professional higher education institutions. The results indicated that evaluation is mostly deemed necessary at the levels of the organisation and the system; from the personal viewpoint of an employee, positive effects of external evaluations are perceived to a lesser degree. The negative influences mentioned were increased bureaucracy, extra work and stress. Top managers of institutions most often saw the positive influences from external evaluations since they help to implement reorganisations and development activities within an organisation. Managers perceived the positive effects of external evaluations on their everyday work as well, more than other employees did. Researchers felt the positive effects of external evaluations least. Nearly a quarter of all employees of higher education institutions do not perceive the effects of external evaluations on their everyday work at all. Employees of professional higher education institutions perceive the positive effects of external evaluations to a greater extent than employees of universities do, indicating that external evaluation has contributed to the development of their organisations. The differences in opinions of the employees of higher education institutions regarding perceived positive and negative impacts of external evaluations—whether on individual, organisation or system points of view—indicate that employees do not identify closely enough with the organisation and its strategic goals.  相似文献   

Lipid peroxide levels and antioxidant status in alcoholic liver disease     

Seema Gupta  Rajesh Pandey  Ranjan Katyal  H. K. Aggarwal  R. P. Aggarwal  S. K. Aggarwal 《Indian journal of clinical biochemistry : IJCB》2005,20(1):67-71

The present study was conducted to evaluate some of the components of antioxidant defense system and oxidative damage in 20 male patients of alcoholic liver disease (ALD). The results were compared with 20 healthy male smokers and 20 healthy male non-smokers volunteers. Patients were subjected to detailed clinical examination and laboratory investigations. Blood samples were collected for estimating reduced glutathione (GSH), total thiols (T-SH) malondialdehyde (MDA), transaminases (AST, ALT), glutathione-S-transferease (GST) and gammaglutamyl transferase (GGT). Serum aspartate amino transferase (AST)/alanine amino transferase (ALT) ratio was significantly (p<0.01) reduced in ALD patients as compared to the controls. However, the core of utility of MDA and GST was found to be significantly (p<0.01) increased in ALD patients compared to controls. There was a significant negative correlation of MDA with both GSH and TSH. Plasma GGT levels were significantly (p<0.01) increased in alcoholics and the enzyme showed a significant positive correlation with MDA. These results give enough evidence of increased oxidative stress and compromised antioxidant defense system in patients with ALD.  相似文献   

Bancroftian filariasis in south east Madhya Pradesh: Pre-control epidemilogical observations     

Vandana Dixit  Ashok V. Kurup  A K Gupta  O M Kataria  G B K S Prasad 《Indian journal of clinical biochemistry : IJCB》1997,12(1):39-43

Lymphatic filariasis caused byWuchereria bancrofti is a major health problem next only to malaria. A study had been conducted to estimate the prevalence of microfilaraemia in a rural endemic community near Raipur. The incidence of microfilaramia in the community was found to be about 14% when studied by night finger prick method. The incidence appears to be more in males as compared to females. The infection rate in vector population i.e.,Culex quinquefasciatus was recorded at a rate of 10%. No relationship could be drawn between the rates of vector and human filarial infections or between the density of vector population and the rate of vector/human infection(s). Prior health education is essential before taking up control and preventive measures in given endemic zone.  相似文献   

Hyperhomocysteinemia,MMPs and Cochlear Function: A Short Review     

Seema Bhargava  Meghaa Shanta Bhargava  Eishaan Kamta Bhargava  LM Srivastava 《Indian journal of clinical biochemistry : IJCB》2016,31(2):148-151

Hyperhomocysteinemia (HHCY) has been demonstrated to affect cochlear microvasculature as well as cochlear epithelial cells directly, with a resultant alteration of the expression of matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitors of metalloproteinases (TIMPs). Hence, ascertaining the optimum concentration of MMPs and TIMPs in the cochlea could help to inhibit hearing loss due to HHCY by the administration of appropriate MMP inhibitors, Since infections/inflammations as well as ototoxic antibiotics have a similar mechanism of otic pathology, the cochlear damage they cause could also be similarly prevented.  相似文献