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| 绞股蓝对实验性高脂血症大鼠血浆脂蛋白代谢及相关酶活性的影响 | |
| 引用本文： | 李香华,周亮,何晓知,唐祥斌,彭雨.绞股蓝对实验性高脂血症大鼠血浆脂蛋白代谢及相关酶活性的影响[J].北京体育大学学报,2007,30(2):206-207,212. |
| 作者姓名： | 李香华 周亮 何晓知 唐祥斌 彭雨 |
| 作者单位： | 1. 湖南理工学院体育系,湖南,岳阳,414006 2. 北京体育大学,北京,100084 3. 长沙理工大学体育系,湖南,长沙,410077 4. 湖南师范大学体育系,湖南,长沙,410081 |
| 基金项目： | 湖南科技厅自然科学基金 |
| 摘 要： | 用高脂饲料喂饲大鼠6周,复制成高脂血症模型,而后进行4周高、低两种剂量的绞股蓝和阳性对照药血脂康进行实验性治疗.给药4周后处死动物,比较血清总胆固醇及甘油三酯含量、血清高密度脂蛋白胆固醇和低密度脂蛋白胆固醇含量,同时测定血浆总脂解酶、脂蛋白脂酶和肝脂酶活性.结果发现,高、低剂量绞股蓝和血脂康均能使血清总胆固醇、甘油三酯和低密度脂蛋白胆固醇含量降低,同时能提高血浆总脂解酶和脂蛋白脂酶活性,高剂量绞股蓝还能显著提高肝脂酶活性.结果提示,绞股蓝具有明显的降低肝脏和血清脂质的作用,可能与提高血浆脂蛋白代谢相关酶的活性有关. |
| 关 键 词： | 高脂血症 脂蛋白 总脂解酶 脂蛋白脂酶 肝脂酶 绞股蓝 实验性 高脂血症 大鼠血浆 脂蛋白代谢 相关酶活性 影响 Rats Hyperglycemia Experimental Effects Enzyme Activity Related Metabolism Lipoprotein 酶的活性 作用 血清脂质 肝脏 高剂量 |
| 文章编号： | 1007-3612(2007)02-0206-03 |
| 修稿时间： | 2006年4月12日 |
The Effects of Gynostemmapentaphyllum on Experimental Hyperglycemia Rats' Plasma Lipoprotein Metabolism and Their Related Enzyme Activity |
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| LI Xiang-Hua,ZHOU Liang,HE Xiao-zhi,TANG Xiang-bin,PENG Yu.The Effects of Gynostemmapentaphyllum on Experimental Hyperglycemia Rats'''' Plasma Lipoprotein Metabolism and Their Related Enzyme Activity[J].Journal of Beijing Sport University,2007,30(2):206-207,212. | |
| Authors: | LI Xiang-Hua ZHOU Liang HE Xiao-zhi TANG Xiang-bin PENG Yu |
| Abstract: | The rats were raised with high fat diet for six weeks and then the model of hyperglycemia was then established.After that,the rats were treated with high or low dose of Gynostemmapentaphyllum and Xiezhikang as a masculine comparison for four weeks.Then,those rats were executed and their plasma TC,TG,LDL-C,HDL-C,PHTA,LPL and HL were compared.The results showed that high and low dose of Gynostemmapentaphyllum could decrease the serum cholesterol,triglyceride and LDL-C remarkably and raise the activity of PHTA and LPL.The high dose of Gynostemmapentaphyllum could also elevate the activity of HL.The results showed that the Gynostemmapentaphyllum can decrease lipid in serum and improve their componential,which may be related with the raised activity of related enzyme. |
| Keywords: | hyperglycemia lipoprotein PHTA LPL HL |
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