| 运动调节CSE/H_2S系统在实验性SD大鼠动脉粥样硬化进程中的作用 |
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| 引用本文： | 刘芳.运动调节CSE/H_2S系统在实验性SD大鼠动脉粥样硬化进程中的作用[J].成都体育学院学报,2010,36(3). |
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| 作者姓名： | 刘芳 |
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| 作者单位： | 西南大学体育学院,重庆,400715 |
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| 摘 要： | 探讨动脉粥样硬化进程中胱硫醚-r-裂解酶/硫化氢(CSE/H2S)系统的变化以及有氧运动对该系统的影响.方法:以实验性动脉粥样硬化(atherosclerosis ,AS)SD大鼠16只做为动物模型,随机分为M组(运动组)每天游泳运动30分钟持续8周(n=8),和不做运动组N(n=8).同时设正常对照组C( n = 8) ,给予普通饲料喂养.然后取静脉血和主动脉组织,分别用沉淀漂浮酶联法、和去蛋白法测定各实验组血中 TC、 TG、 LDL、 HDL、H2S含量,用亚甲基蓝法主动脉组织中诱导型胱硫醚-r-裂解酶的活性.结果:8周末与对照组比较,发现模型组M、N血脂水平明显升高,血浆中H2S含量下降,CSE 活性减少,与C组相比差异有显著性.
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| 关 键 词： | 动脉粥样硬化 胱硫醚-r-裂解酶 硫化氢 有氧运动 |
Effect of the CSE/H_2S System of Exercise Intervention on Atherosclerosis of the Experimental SD Rat |
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| Liu Fang.Effect of the CSE/H_2S System of Exercise Intervention on Atherosclerosis of the Experimental SD Rat[J].Journal of Chengdu Physical Education Institute,2010,36(3). |
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| Authors: | Liu Fang |
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| Institution: | Liu Fang(Physical Education College,Southwest University,Chongqing 400715) |
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| Abstract: | Objective: To investigate changes in the CSE/H2S system in the process of atherosclerosis as well as the effect of aerobics on the system.Methods: 16 SD rats of experimental atherosclerosis are made into models and randomly divided into the M group and the N group,with M group swimming 30 minutes each day for eight weeks on end,while the N group not doing any exercise.At the same time,the control group is fed normally.Then levels of serum lipids and serum H2S are determined by the immunohistochenistry techn... |
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| Keywords: | atherosclerosis cystathionine-r-lyase hydrogen sulphide aerobics |
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