| 运动性疲劳对大鼠海马一氧化氮合成酶活性的影响 |
| |
| 引用本文： | 曹电康,刘鸿宇,续俊,姚晋宏,白莉芳.运动性疲劳对大鼠海马一氧化氮合成酶活性的影响[J].北京体育大学学报,2005,28(12):1647-1648. |
| |
| 作者姓名： | 曹电康 刘鸿宇 续俊 姚晋宏 白莉芳 |
| |
| 作者单位： | 中北大学运动人体科学实验中心,山西,太原,030051 |
| |
| 基金项目： | 中北大学校科研和教改项目 |
| |
| 摘 要： | 为了探讨海马一氧化氮合成酶(NOS)与运动性疲劳的关系,研究了运动性疲劳对大鼠海马NOS活性的影响.经4周大强度游泳训练制成大鼠运动疲劳模型,在安静状态下,用放射免疫学方法检侧了大鼠海马NOS总活性.结果表明:疲劳组大鼠海马NOS总活性大于对照组(P<0.05).说明:运动性疲劳作为一种应激可使大鼠海马神经元中的NOS上调,海马NOS神经元参与了中枢运动性疲劳的形成,其机理可能与海马神经元对应激反应的心理、行为、内分泌调节以及NO的神经毒性有关.
|
| 关 键 词： | 运动性疲劳 海马 一氧化氮合成酶(NOS) 大鼠 运动 性疲劳 大鼠海马神经元 一氧化氮合成酶活性 影响 Nitric Oxide Synthase Activity Fatigue Effects Research 神经毒性 内分泌调节 行为 心理 应激反应 机理 中枢 对照组 结果 方法 |
| 文章编号： | 1007-3612(2005)12-1647-02 |
| 修稿时间： | 2004年6月23日 |
Research on Effects of Exercise-induced Fatigue on Activity of Nitric Oxide Synthase (NOS) in Rat hippocampus |
| |
| CAO Dian-kang,LIU Hong-yu,XU Jun,YAO Jing-hong,BAI Li-fang.Research on Effects of Exercise-induced Fatigue on Activity of Nitric Oxide Synthase (NOS) in Rat hippocampus[J].Journal of Beijing Sport University,2005,28(12):1647-1648. |
| |
| Authors: | CAO Dian-kang LIU Hong-yu XU Jun YAO Jing-hong BAI Li-fang |
| |
| Abstract: | In order to explore the relationship between exercise-induced fatigue and nitric oxide synthase(NOS) in hippocampus,this study explored effects of exerciseinduced fatigue on expression of NOS in rat hippocampus.After four-week swimming exercise with high-level intensity,under the quiet situation,the general NOS activity in rat hippocampus was tested adopted radioimmunological technique.The results of this study indicated that there existed a significant increase of the general NOS activity in rat hippocampus in fatigue group(P<0.05).It was concluded that exercise-induced fatigue as a stress can inspire upregulated expression of NOS in hippocampus,which was involved in forming of exercise-induced central fatigue.It was proposed that it was due to the psychological,behavioral,endocrine regulation of hippocampus on stress,and NO neurotoxicity. |
| |
| Keywords: | exercise-induced fatigue hippocampus nitric oxide synthase(NOS) rat |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
