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1.
Colak T Akca T Turkmenoglu O Canbaz H Ustunsoy B Kanik A Aydin S 《Journal of Zhejiang University. Science. B》2008,9(4):319-323
Objective: This prospective randomized clinical trial was conducted to evaluate the necessity of drainage after total thyroidectomy or lobectomy for benign thyroidal disorders. Methods: A total of 116 patients who underwent total thyroidectomy or lobectomy for benign thyroidal disorders were randomly allocated to be drained or not. Operative and postoperative outcomes including operating time, postoperative pain assessed by visual analogue scale (VAS), total amount of intramuscular analgesic administration, hospital stay, complications, necessity for re-operation and satisfaction of patients were all assessed. Results: The mean operating time was similar between two groups (the drained and non-drained groups). The mean VAS score was found to be significantly low in the non-drained group patients in postoperative day (POD) 0 and POD 1. The mean amount of intramuscular analgesic requirement was significantly less in the non-drained group. One case of hematoma, two cases of seroma and three cases of transient hypoparathyroidism occurred in the non-drained group, whereas one case of hematoma, two cases of seroma, two cases of wound infections and two cases of transient hypoparathyroidism occurred in the drained group. No patient needed re-operation for any complication. The mean hospital stay was significantly shorter and the satisfaction of patients was superior in the non-drained group. Conclusion: These findings suggest that postoperative complications cannot be prevented by using drains after total thyroidectomy or lobectomy for benign thyroid disorders. Furthermore, the use of drains may increase postoperative pain and the analgesic requirement, and prolong the hospital stay. In the light of these findings, the routine use of drains might not be necessary after thyroid surgery for benign disorders. 相似文献
2.
目的观察蒙脱石和氯己定联合治疗复发性口疮的疗效。方法复发性口疮病人 68例 ,随机分成A、B两组。A组为蒙脱石和 2 %氯己定联合治疗 34例 (男性 1 6例 ,女性1 8例 ) ;B组为 2 %氯己定、口服维生素B2 、维生素C、甲硝唑治疗 34例 (男性 1 4例 ,女性 2 0例 )。结果A组总有效率为 98 83% ,B组总有效率为 82 1 9%。两组比较差异有显著意义 (P <0 0 1 )。结论蒙脱石和氯己定联合治疗复发性口疮疗效更佳。 相似文献
3.
Xiao-hong Pan Ying-xue Chen Mei-xiang Xiang Geng Xu Jian-an Wang 《Journal of Zhejiang University. Science. B》2010,11(10):754-761
A meta-analysis was performed to address the efficacy and safety of paclitaxel-eluting stent (PES) in ST-segment elevation
myocardial infarction (STEMI) patients. A systematic literature search was conducted to identify all randomized clinical trials
in mortality, recurrent myocardial infarction (rMI), repeat revascularization (RR), and stent thrombosis (ST). A total of
4190 STEMI patients were enrolled in six randomized trials comparing PES with bare-metal stent (BMS). The pooled repeat revascularization
rate was 5.7% in PES group, significantly lower than 10.0% in BMS group with an odds ratio (OR) of 0.56, 95% confidence interval
(CI) [0.44, 0.72] (P<0.00001). No significant difference was found between PES and BMS groups in mortality at one year after the indexing procedure
(3.9% vs. 5.1%, OR 0.88, 95% CI [0.63, 1.21], P=0.42). Similarly, rMI rate did not differ significantly between the two groups (3.4% vs. 4.1%, OR 0.80, 95% CI [0.56, 1.13],
P=0.21). PES was also associated with the comparable pooled rate of definite stent thrombosis with BMS (2.3% vs. 2.4%, OR 0.81,
95% CI [0.52, 1.26], P=0.35). The results show that PES improved clinical outcomes in STEMI patients with a decreased need for repeat revascularization
and no concerns for safety. 相似文献
4.
Anticoagulation therapy in intra-aortic balloon counterpulsation: Does IABP really need anti-coagulation? 总被引：1，自引：0，他引：1
INTRODUCTIONTheintra aorticballoonpump(IABP)isthemostwidelyusedofallcirculatoryassistdevicestodayandisroutinelyusedinawiderangeofse riouscardiovascularconditions,rangingfromhe modynamicinstabilityinpatientssufferingfromcomplicationsofacutemyocardialinfarc… 相似文献
5.
An unembalmed cadaveric preparation for simulating pleural effusion: A pilot study of chest percussion involving medical students 
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下载免费PDF全文 Cadaveric simulations are an effective way to add clinical context to an anatomy course. In this study, unembalmed (fresh) cadavers were uniquely prepared to simulate pleural effusion to teach chest percussion and review thoracic anatomy. Thirty first‐year medical students were assigned to either an intervention (Group A) or control group (Group B). Group A received hands‐on training with the cadaveric simulations. They were instructed on how to palpate bony landmarks for identifying the diaphragm and lobes of the lungs, as well as on how to properly perform chest percussion to detect abnormal fluid in the pleural space. Students in Group B practiced on each other. Students in Group A benefited from the training in several ways. They had more confidence in their percussive technique (A = mean 4.3/5.0, B = 2.9/5.0), ability to count the ribs on an intact body (A = mean 4.0/5.0, B = 3.0/5.0), and ability to identify the lobes of the lungs on an intact body (A = mean 3.8/5.0, B = 2.3/5.0). They also demonstrated a greater ability to locate the diaphragm on an intact body (A = 100%, B = 60%) and detect abnormal pleural fluid (A = 93%, B = 53%) with greater confidence (A = mean 3.7/5.0, B = 2.5/5.0). Finally, the hands‐on training with the unembalmed cadavers created more excitement around learning in Group A compared with Group B. This study shows that simulating pleural effusion in an unembalmed cadaver is a useful way to enhance anatomy education. Anat Sci Educ 10: 160–169. © 2016 American Association of Anatomists. 相似文献
6.
应用不同选色方法对临床烤瓷修复效果的影响 总被引：2，自引：0，他引：2
[目的]初探应用不同比色方法对临床烤瓷修复效果的影响.[方法]A组选择诊室日光灯下进行人工和电脑选色,部位在修复体对称牙或邻牙的颈1/3、中1/3和切1/3分别比色;B组在不同光源下,多次进行人工和电脑选色.首先在日光灯下选色,然后在窗前选色,最后在中午时分北向的日光下终选色,选色部位如A组.[结果]临床成功病例结果经卡方分析表明:A组电脑和人工选色之间有显著性差异P<0.05;A组和B组之间应用人工选色有显著性差异P<0.05,而应用电脑选色无显著性差异P>0.05;B组应用电脑与人工选色之间无显著性差异.P>0.05.[结论]应用电脑选色不受外界环境因素的影响,比人工选色要客观;人工选色应尽量在多种光源下多次选色. 相似文献
7.
Objective: To investigate if intra-aortic balloon pump(IABP) is contraindicated without anticoagulation therapy. Methods:
Some 153 IABP patients in the King Abdulaziz Cardiac Center(KSA) were randomly assigned into two groups. Anticoagulation group
(Group A) consisted of 71 patients who were given heparin intravenously with target aPTT50–70 seconds. Non-anticoagulation
group (Group B) consisted of 82 patients without intravenous heparin during balloon pumping. Hematological parameters including
platelet count, D-dimer, Plasminogen activator inhibitor-1 (PAI-1) and fibrinogen degradation products (FDP) were checked
respectively at the point of baseline, 24 hours, 48 hours and 24 hours post IABP counterpulsation. Clot deposits on balloon
surface, vascular complications from IABP including bleeding and limb ischemia were recorded. Results: Platelet count and
PAI-1 level decreased at 24 hours and 48 hours in both groups (P<0.05). D-dimer dimer and FDP level increased at 24 hours and 48 hours in both groups(P<0.05), but returned to the baseline level 24 hours post IABP removal (P>0.05). Three patients in Group A and 2 patients in Group B developed minor limb ischemia (P>0.05). No major limb ischemia in either group. Two patients in Group A suffered major bleeding and required blood transfusion
or surgical intervention, whereas no patient had major bleeding in Group B. Eight patients had minor bleeding in Group A,
but only 2 patients in Group B (P<0.05). No clot deposit developed on IABP surface in either group. Conclusion: IABP is safe without routine anticoagulation
therapy. Selecting appropriate artery approach and early detection intervention are key methods for preventing complications. 相似文献
8.
Wen-hua RUAN Mei-li HUANG Xiao-lei HE Feng ZHANG Hai-biao TAO 《Journal of Zhejiang University. Science. B》2013,14(3):253-258
Objective:To evaluate the pharmacological effects of traditional Chinese medicine,bear bile capsule and Huangqi granule,on recurrent parotitis in children.Methods:In this prospective,controlled,and randomized study,a total of 151 young children were divided into three groups:Group A included massaging the children’s parotid region and melting vitamin C in their mouth daily;Group B included swallowing bear bile capsule and Huangqi granule daily;and Group C included massages and vitamin C as prescribed in Group A,and traditional Chinese medicine as prescribed in Group B.Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years.Analysis of variance(ANOVA) and Ridit analysis were employed for statistical analysis.Results:The recurrence rate decreased in every group,but was significantly more in Groups B and C when compared to Group A.The recurrences significantly decreased(P<0.01) in Group B and their recovery rate was as high as 63%,significantly better than those of the other groups(P<0.01).Conclusions:Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children. 相似文献
9.
10.
Sunil Jonathan Holla Kalpana Ramachandran Bina Isaac Shajan Koshy 《Anatomical sciences education》2009,2(4):179-183
Authors report here a survey of medical student feedback on the effectiveness of two different anatomy curricula at Christian Medical College, Vellore, India. Undergraduate medical students seeking the Bachelor in Medicine and Bachelor in Surgery (M.B.B.S.) degrees were divided into two groups by the duration of their respective anatomy curriculum. Group 1 students had completed a longer, 18‐month curriculum whereas Group 2 counterparts followed a shorter, 12‐month curriculum. Students' responses to a questionnaire were studied. Analysis of feedback from Groups 1 and 2 contrasted the effectiveness of the two anatomy curricula. The coverage of gross anatomy was rated adequate or more than adequate by 98% of Group 1 and 91% of Group 2. A desire for greater emphasis on gross anatomy teaching was expressed by 24% of Group 1 and 50% of Group 2 (P = 0.000). Two‐thirds of all students felt that the one‐year program was not adequate, and 90% of Group 1 and 74% of Group 2 felt that clinically oriented anatomy teaching required more emphasis. Dissection was helpful or very helpful for 94% of Group 1 and 88% of Group 2. This study suggests that a better understanding of gross anatomy was gained from a course of longer duration (18 months with 915 contact hr vs. 12 months with 671 contact hr). Students who completed the longer anatomy course had greater appreciation of the need for clinically oriented anatomy teaching and dissection. Anat Sci Educ 2:179–183, 2009. © 2009 American Association of Anatomists. 相似文献
11.
目的:探求适用于低收入人群十二指肠溃疡(DU)患者经济、有效的治疗方案。方法:将156例活动性DU患者随机分成2组,治疗组82例,用呋喃唑酮200mg、乐得胃2片每天三次,法莫替丁20mg早晚各一次治疗2周:对照组74例,用羟氨苄青霉素500mg、胶体果胶铋100mg(以Bi计)每天三次,奥美拉唑40mg每天早晨一次治疗2周,疗程结束时复查胃镜观察溃疡愈合情况,疗程结束后4周取胃粘膜检查幽门螺杆菌(HP),观察HP根除情况。结果:治疗组和对照组对DU有效率分别为93.6％和94.5％,无统计学差异(P>0.05),HP根除率分别为82.3％和95.7％,对照组明显高于治疗组(P<0.01);治疗组2例出现白细胞轻度降低(3.5×10~9/L),对照组1例ALT轻度升高,治疗结束后均恢复,余无严重不良反应。呋喃唑酮、乐得胃、法莫替丁联合治疗DU,虽然HP根除率稍低,但经济、安全、有效,尤其适用于低收入患者。 相似文献
12.
雷雯 《洛阳师范学院学报》2012,(11):82-86
采用元分析法,使用国际Cochrane协作组织提供的Review Manage 4.2软件,对健美操锻炼与心血管机能关系的40篇文献的数据进行定量化综合分析.结果表明:健美操锻炼对安静心率的总效果量d=-0.68,95%置信区间为[-0.73,-0.62],P<0.01,具有统计学显著性意义,效果量为中;对收缩压的总效果量d=-0.48,95%置信区间为[-0.80,-0.17],P<0.01,具有统计学显著性意义,效果量为小;对舒张压的总效果量d=-0.15,95%置信区间为[-0.35,0.06],且Z=1.40,P〉0.05,其效果量不具有统计学显著性差异. 相似文献
13.
本实验采集4头波尔山羊种公羊精液,比较4种精液冷冻保存稀释液配方[A葡萄糖-柠檬酸钠-乙二胺四乙酸;B乳糖-葡萄糖-柠檬酸钠;C葡萄糖-柠檬酸钠-三羟甲基氨基甲烷;D蔗糖-葡萄糖-柠檬酸-谷氨酸-三羟甲基氨基甲烷]并进行细管和颗粒不同冻精制作,测定解冻后精子活率、畸形率、顶体完整率.结果表明,D稀释液解冻后的精子活率平均为40.50%,顶体完整率50.25%,优于A和B液,呈显著或极显著差异(P<0.05,P<0.01),而C稀释液解冻后的精子活率平均为38.5%,顶体完整率48.48%,优于A和B(P<0.05);细管冻精效果优于颗粒冻精(P<0.05).结论:最佳处理方式为利用D稀释液配方进行细管冻精. 相似文献
14.
Xin-xin Xu Lian-bao Cao Zhe Wang Zhen Xu Bing-qian Zhang She-ling Wu Sha-sha Qi Lei Yan Zi-jiang Chen 《Journal of Zhejiang University. Science. B》2018,19(5):383-389
The pathogenesis and therapeutic treatment of intrauterine adhesions (IUAs) remain unsolved, highlighting the need for stable and effective experimental animal models. In this study, uterine electrocoagulation of twenty-one female New Zealand White rabbits was carried out to establish an IUA model. As rabbits have two completely separate uterine horns, each rabbit had its own internal control: one uterine horn was given an electrothermal injury (Group A, n=21), and the contralateral uterine horn received no treatment and served as the control (Group B, n=21). The endometrial morphology, number of endometrial glands, area of endometrial fibrosis, and number of implanted fetuses were compared between the two groups. In Group A, the numbers of endometrial glands on Days 7 and 14 and the number of implanted fetuses were significantly lower than those in Group B (P<0.05, P<0.05, and P<0.01, respectively), while the ratio of the area with endometrial stromal fibrosis to the total endometrial area was significantly increased (P<0.01). These results suggest that this method of electrothermal injury is effective for the establishment of a rabbit IUA model between 7 and 14 d after surgery. 相似文献
15.
Reflecting on how “the very nature of language learning has changed”(New London Group [NLG], 1996, p. 64), this article describes an inquiry-driven teaching approach to middle school English. Looking at student outcomes utilizing Google’s 20% approach, this study explored how mentorship, digital tools, and student interests provide “opportunities [for students] to find their own voices” (NLG, 1996, p. 71). In particular, this article analyzes student inquiry based on the 4 pedagogical foundations of multiliteracies: situated practice, overt instruction, critical framing, and transformed practice. By focusing on the voices and experiences of students, this framework highlights what multiliteracies can look like within classrooms. Ultimately, this study of literacies within inquiry-driven classrooms responds to the call of multiliteracies research from 20 years ago that, “Students need to develop the capacity to speak up, to negotiate, and to be able to engage critically with the conditions of their working lives” (New London Group, 1996, p. 67). 相似文献
16.
目的：比较多种模式联合镇痛与单纯术后镇痛在膝关节置换术中的镇痛效果。方法：选取2009年1月至2013年8月入院拟行人工全膝关节置换术的患者共80例,随机分为多种模式联合镇痛组（A组）及单纯术后镇痛组（B组）。分别记录两组患者术后各时间段静息痛的疼痛评分、膝关节活动度进行统计学分析。结果：A组与B组患者术后72 h内各时间段疼痛评分,差异有统计学意义（P〈0.05）,术后72 h内两组患者膝关节活动度,差异有统计学差异（P〈0.05）。结论：多种模式联合镇痛应用于膝关节置换术围手术期镇痛及促进患者术后早期膝关节主动活动是有效、安全的。具有使用安全、副作用少、易于推广的特点。 相似文献
17.
Chen XC Weng J Chen XQ Du JZ Zhu MP Pan YQ Liu M 《Journal of Zhejiang University. Science. B》2008,9(9):739-746
Objective: To study the relationships among magnetic resonance imaging (MRI), histological findings, and insulin-like growth factor-I (IGF-I) in steroid-induced osteonecrosis of the femoral head in rabbits. Methods: Thirty rabbits were randomly divided into experimental Group A (n=15) and control Group B (n=15). The 7.5 mg/kg (2 ml) ofdexamethasone (DEX)and physiological saline (2 ml) were injected into the fight gluteus medius muscle twice at one-week intervals in animals of Groups A and B, respectively. At 4, 8 and 16 weeks after obtaining an MRI, the rabbits were sacrificed and the femoral head from one side was removed for histological study of lacunae empty of osteocytes, subchondral vessels, and size of fat cells under microscopy, and the femoral head from the other side was removed for enzyme-linked immunoadsorbent assay (ELISA) for IGF-I.Results: At 4, 8 and 16 weeks after treatment, no necrotic lesions were detected in Group B, while they were detected in Group A.Light microscopy revealed that the fat cells of the marrow cavity were enlarged, subchondral vessels were evidently decreased,and empty bone lacunae were clearly increased. The IGF-I levels in Group A were significantly higher than those in Group B. At 8 weeks after the DEX injection, the MRI of all 20 femora showed an inhomogeneous, low signal intensity area in the femoral head,and at 16 weeks, the findings of all 10 femora showed a specific "line-like sign". The MRI findings of all femora in Group B were normal. Conclusion: MRI is a highly sensitive means of diagnosing early experimental osteonecrosis of the femoral head. However, the abnormal marrow tissues appeared later than 4 weeks when the expression of IGF-I increased. This reparative factor has an early and important role in response to steroid-induced osteonecrosis of the femoral head, and provides a theoretical foundation for understanding the pathology and designing new therapies. 相似文献
18.
在格区间集合[L]上定义t-T模及其广义逆算子αT,研究它们的性质,利用它们给出群G上格区间值Fuzzy子集组成的集合中[L]G元素的sup-T合成运算和inf-αT合成运算,得到这些运算的代数性质以及一些重要的关系式。 相似文献
19.
In order to examine the relationship between broad personality traits and learning approaches, 852 university students completed the NEO-FFI [Costa, P. T., Jr., & McCrae, R. R. (1992). Revised NEO Personality Inventory (NEO-PI-R) and NEO Five-Factor Inventory (NEO-FFI): Professional manual. Odessa, FL: Psychological Assessment Resources] and SPQ [Biggs, J. B. (1987). The Study Process Questionnaire manual. Victoria: Australian Council for Educational Research], which assess personality and learning approaches, respectively. Seven previous studies were used to generate hypotheses on the relationship between these two measures, but only the positive link between Openness to Experience and Deep learning was supported by both correlational and structural equation modelling tests. Openness was also found to be negatively linked to Surface learning, but other Big Five traits were not saliently associated with learning approaches. Results indicate that the overlap between learning approaches and personality traits is lower than previously suggested. Implications are discussed. 相似文献
20.
Effects of β-Aescin on the expression of nuclear factor-κB and tumor necrosis factor-α after traumatic brain injury in rats 总被引：9，自引：0，他引：9
To investigate the inhibiting effect of β-Aescin on nuclear factor-κB(NF-κB)activation and the expression of tumornecrosis factor-α(TNF-α)protein after traumatic brain injury(TBI)in the rat brain,62 SD rats were subjected to lateral corticalimpact injury caused by a free-falling object and divided randomly into four groups:(1)sham operated(Group A);(2) injured(Group B);(3)β-Aescin treatment(Group C);(4) pyrrolidine dithocarbamate(PDTC) treatment(Group D).β-Aescin was ad-ministered in Group C and PDTC treated in Group D immediately after injury.A series of brain samples were obtained directly 6h,24 h and 3 d respectively after trauma in four groups.NF-κB activation was examined by Electrophoretic Mobility Shift Assay(EMSA);the levels of TNF-α protein were measured by radio-immunoassay(RIA);the water content of rat brain was measuredand pathomorphological observation was carried out.NF-κB activation,the levels of TNF-α protein and the water content of ratbrain were significantly increased(P＜0.0 相似文献