共查询到20条相似文献，搜索用时 562 毫秒
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近十年,生物高分子材料的发展突飞猛进,国内外学者对于医学应用领域中炙手可热的生物高分子——壳聚糖的研究更是有如井喷之势。本文综述了近几年国内外学者在组织工程应用研究领域中的多种壳聚糖复合支架的制备方法及其特性,尤其着重综述了骨组织工程领域和皮肤组织工程领域中的多种壳聚糖复合支架的制备方法和特性。并对壳聚糖复合支架在组织工程中的发展进行了展望,认为增强支架的生物相容性,提高复合支架的力学性能,将是未来几年中壳聚糖复合支架研究的重心所在。 相似文献
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介绍了生物可降解高分子的定义与生物可降解高分子的分类。重点分类阐述了几类生物可降解高分子的合成与制备方法及生物可降解高分子的几个重要应用领域,指出了其应用潜力及应用前景。 相似文献
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生物可降解高分子的合成及其应用研究进展 总被引：1，自引：0，他引：1
介绍了生物可降解高分子的定义与生物可降解高分子的分类.重点分类阐述了几类生物可降解高分子的合成与制备方法及生物可降解高分子的几个重要应用领域,指出了其应用潜力及应用前景. 相似文献
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高性能混凝土是一种满足特殊性能组合要求,其制备的主要技术途径是掺优质活性掺和料和高效减水剂,使高性能混凝土变得既经济又具有环境生态保护作用。本文主要研究I级粉煤灰、矿渣微粉二者双掺高性能混凝土（HPC）试验其工作性能和力学性能,并在重点工程中得到了应用。 相似文献
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水泥基材料的微观力学性能与结构特征决定了其宏观力学及耐久性能,纳米压痕能够测定硬化水泥浆体微观结构各相的力学性能。本文介绍了纳米压痕测试技术在水泥基材料中的样品制备方法及试验方案,结合统计纳米压痕技术、相关电镜及微观测试方法,详细分析了水泥基材料中微/纳观组分及力学性能和加入细掺料的水泥基材料组分及力学性能的变化特征,同时分析了水泥基材料界面区微观力学性能,尤其对硬化后水泥浆体中大量存在并显著影响水泥基材料的水化硅酸钙(C-S-H)凝胶物理化学性能变化规律进行了重点分析,为今后纳米压痕测试在水泥基材料中的应用推广,建立水泥基材料微观力学性能与宏观性能之间的联系提供借鉴。 相似文献
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We present facile strategies for the fabrication of two types of microfluidic devices made of hydrogels using the natural biopolymers, alginate, and gelatin as substrates. The processes presented include the molding-based preparation of hydrogel plates and their chemical bonding. To prepare calcium-alginate hydrogel microdevices, we suppressed the volume shrinkage of the alginate solution during gelation using propylene glycol alginate in the precursor solution along with sodium alginate. In addition, a chemical bonding method was developed using a polyelectrolyte membrane of poly-L-lysine as the electrostatic glue. To prepare gelatin-based microdevices, we used microbial transglutaminase to bond hydrogel plates chemically and to cross-link and stabilize the hydrogel matrix. As an application, mammalian cells (fibroblasts and vascular endothelial cells) were cultivated on the microchannel surface to form three-dimensional capillary-embedding tissue models for biological research and tissue engineering. 相似文献
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The successful encapsulation of human hepatocellular carcinoma (HepG2) cells would greatly assist a broad range of applications in tissue engineering. Due to the harsh conditions during standard chitosan fiber fabrication processes, encapsulation of HepG2 cells in chitosan fibers has been challenging. Here, we describe the successful wet-spinning of chitosan-alginate fibers using a coaxial flow microfluidic chip. We determined the optimal mixing conditions for generating chitosan-alginate fibers, including a 1:5 ratio of 2% (w∕w) water-soluble chitosan (WSC) solution to 2% (w∕w) alginate solution. Ratio including higher than 2% (w∕w) WSC solution increased aggregation throughout the mixture. By suspending cells in the WSC-alginate solution, we successfully fabricated HepG2 cell-laden fibers. The encapsulated HepG2 cells in the chitosan-alginate fibers were more viable than cells encapsulated in pure alginate fibers, suggesting that cross-linked chitosan provides a better environment for HepG2 cells than alginate alone. In addition, we found that the adhesion of HepG2 cells on the chitosan-alginate fiber is much better than that on the alginate fibers. 相似文献
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There are a plethora of approaches to construct microtissues as building blocks for the repair and regeneration of larger and complex tissues. Here we focus on various physical and chemical trapping methods for engineering three-dimensional microtissue constructs in microfluidic systems that recapitulate the in vivo tissue microstructures and functions. Advances in these in vitro tissue models have enabled various applications, including drug screening, disease or injury models, and cell-based biosensors. The future would see strides toward the mesoscale control of even finer tissue microstructures and the scaling of various designs for high throughput applications. These tools and knowledge will establish the foundation for precision engineering of complex tissues of the internal organs for biomedical applications. 相似文献
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高等职业教育的＂职业性＂、修订后的《教学要求》和现有高职英语教材的使用现状显示了建设具有职业特色的高职英语教材的必要性。以需求分析为前提、以多方参与编选教材为途径、以工作任务为导向、以职业技能实训教材的编写为重点、以立体化教材为形式、以不同专业、层次为基准是建设彰显职业特色的高职英语教材体系的几个对策。 相似文献
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介绍了共混法和插层复合法两种PE纳米塑料的制备方法，纳米粒子填充到PE中表现出良好的力学性能、耐磨性能、加工性能、电学性能、磁性能和热性能．概述了PE纳米塑料的研究进展情况，指出目前聚乙烯纳米塑料的研究、开发和应用还处于起步阶段，有待研究的理论和实际问题还很多，但作为一种重要的新型材料，其应用必将具有广阔的前景。 相似文献
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本文通过对机械制图与CAD的关系分析,指出三维几何造型是制图课程教改的内容之一,利用多媒体在机械制图几何画法和绘制组合体三视图等教学过程中运用CAD软件三维几何造型,充分发挥学生想象力,提高学生识图和绘图能力,培养设计和创新意识等;通过CAD二维辅助和三维几何造型训练,学生不仅了解了CAD软件,且能够认识到这种现代工具进行工程设计的便捷、准确性,以及CAD技能对工科大学生的重要性。 相似文献
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Flexible batteries, which maintain their functions potently under various mechanical deformations, attract increasing interest due to potential applications in emerging portable and wearable electronics. Significant efforts have been devoted to material synthesis and structural designs to realize the mechanical flexibility of various batteries. Carbon nanotubes (CNTs) have a unique one-dimensional (1D) nanostructure and are convenient to further assemble into diverse macroscopic structures, such as 1D fibers, 2D films and 3D sponges/aerogels. Due to their outstanding mechanical and electrical properties, CNTs and CNT-based hybrid materials are superior building blocks for different components in flexible batteries. This review summarizes recent progress on the application of CNTs in developing flexible batteries, from closed-system to open-system batteries, with a focus on different structural designs of CNT-based material systems and their roles in various batteries. We also provide perspectives on the challenges and future research directions for realizing practical applications of CNT-based flexible batteries. 相似文献
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This paper reviews our work on the application of ultrafast pulsed laser micro∕nanoprocessing for the three-dimensional (3D) biomimetic modification of materials surfaces. It is shown that the artificial surfaces obtained by femtosecond-laser processing of Si in reactive gas atmosphere exhibit roughness at both micro- and nanoscales that mimics the hierarchical morphology of natural surfaces. Along with the spatial control of the topology, defining surface chemistry provides materials exhibiting notable wetting characteristics which are potentially useful for open microfluidic applications. Depending on the functional coating deposited on the laser patterned 3D structures, we can achieve artificial surfaces that are (a) of extremely low surface energy, thus water-repellent and self-cleaned, and (b) responsive, i.e., showing the ability to change their surface energy in response to different external stimuli such as light, electric field, and pH. Moreover, the behavior of different kinds of cells cultured on laser engineered substrates of various wettabilities was investigated. Experiments showed that it is possible to preferentially tune cell adhesion and growth through choosing proper combinations of surface topography and chemistry. It is concluded that the laser textured 3D micro∕nano-Si surfaces with controllability of roughness ratio and surface chemistry can advantageously serve as a novel means to elucidate the 3D cell-scaffold interactions for tissue engineering applications. 相似文献