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1.
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2.
Low energy availability, defined as low caloric intake relative to exercise energy expenditure, has been linked to endocrine alterations frequently observed in chronically energy-deficient exercising women. Our goal was to determine the endocrine effects of low energy availability in exercising men. Six exercising men (VO2peak: 49.3 ± 2.4 ml · kg?1 · min?1) underwent two conditions of low energy availability (15 kcal · kg?1 fat-free mass [FFM] · day?1) and two energy-balanced conditions (40 kcal · kg?1 FFM · day?1) in randomised order. During one low energy availability and one balanced condition, participants exercised to expend 15 kcal · kg?1 FFM · day?1; no exercise was conducted during the other two conditions. Metabolic hormones were assessed before and after each 4-day period. Following both low energy availability conditions, leptin (?53% to ?56%) and insulin (?34% to ?38%) were reduced (P < 0.05). Reductions in leptin and insulin were independent of whether low energy availability was attained with or without exercise (P > 0.80). Low energy availability did not significantly impact ghrelin, triiodothyronine, testosterone and IGF-1 (all P > 0.05). The observed reductions in leptin and insulin were in the same magnitude as changes previously reported in sedentary women. Further research is needed to understand why other metabolic hormones are more robust against low energy availability in exercising men than those in sedentary and exercising women.  相似文献   

3.
Many physically active individuals have undertaken intermittent fasting to reduce their daily caloric intake. However, abstaining from meals for a specific length of time may lead to the acute disturbance of highly carbohydrate-dependent exercise performance. The purpose of this study was to observe the effect of 10 days of intermittent fasting on high-intensity type exercises, Wingate anaerobic (WT) and prolonged high-intensity time-to-exhaustion (HIT) cycling test. Twenty participants were randomised into an intermittent fasting (FAS) and a control group (CON). One day after baseline data collection on Day-0 where participants consumed their recommended daily caloric intake (FAS?=?2500?±?143?kcal?day?1; CON?=?2492?±?20?kcal?day?1) served over a course of five meals, the FAS group consumed only four meals where 40% was restricted by the omission of lunch (FAS?=?1500?±?55?kcal?day?1). This diet was then continued for 10 days. Data on exercise performance and other dependent variables were collected on Day-2, -4, -6, -8 and -10. A reduction in WT power in the FAS group was observed on Day-2 (821.74?±?66.07?W) compared to Day-0 (847.63?±?95.94?W) with a moderate effect size (p?p?p?相似文献   

4.
Exercise testing on motorised treadmills provides valuable information about running performance and metabolism; however, the impact of treadmill type on these tests has not been investigated. This study compared the energy demand of running on two laboratory treadmills: an HP Cosmos (C) and a Quinton (Q) model, with the latter having a 4.5 times stiffer running platform. Twelve experienced runners ran identical bouts on these treadmills at a range of four submaximal velocities (reported data is for the velocity that approximated 75–81% VO2max). The stiffer treadmill elicited higher oxygen consumption (C: 46.7 ± 3.8; Q: 50.1 ± 4.3 ml·kg?1 · min?1), energy expenditure (C: 16.0 ± 2.5; Q: 17.7 ± 2.9 kcal · min?1), carbohydrate oxidation (C: 9.6 ± 3.1; Q: 13.0 ± 3.9 kcal · min?1), heart rate (C: 155 ± 16; Q: 163 ± 16 beats · min?1) and rating of perceived exertion (C: 13.8 ± 1.2; Q: 14.7 ± 1.2), but lower fat oxidation (C: 6.4 ± 2.3; Q: 4.6 ± 2.5 kcal · min?1) (all analysis of variance treadmill comparisons P < 0.01). This study confirms that caution is required when comparing performance and metabolic results between different treadmills and suggests that treadmills will vary in their comparability to over-ground running depending on the running platform stiffness.  相似文献   

5.
This study aimed to describe the body composition and physiological changes which take place during the in-season and recovery periods of a group of natural bodybuilders. Natural male bodybuilders (n?=?9) were assessed 16 (PRE16), 8 (PRE8), and 1 (PRE1) week(s) before, and 4 (POST4) weeks after a bodybuilding competition. Assessments included body composition, resting metabolic rate (RMR), serum hormones, and 7-day weighed food and training diaries. Change in parameters was assessed using repeated-measures analysis of variance. Dietary protein intake remained high throughout the study period (2.8–3.1?g?kg?1?d?1). Fat mass (FM) was significantly reduced from PRE16 to PRE1 (8.8?±?3.1 vs. 5.3?±?2.4?kg, P?.01). There was a small decrease in lean mass (LM) from PRE8 to PRE1 (71.8?±?9.1 vs. 70.9?±?9.1?kg, P?P?>?.05). Large reductions in total and free testosterone (16.4?±?4.4 vs. 10.1?±?3.6?nmol?L?1, P?. 116.8?±?76.9?pmol?L?1, P?. 19.9?±?7.6?nmol?L?1, P?. 72.5?±?8.5?kg, P?. 25.4?±?9.3?nmol?L?1, P?相似文献   

6.
Abstract

It has been shown that the critical power (CP) in cycling estimated using a novel 3-min all-out protocol is reliable and closely matches the CP derived from conventional procedures. The purpose of this study was to assess the predictive validity of the all-out test CP estimate. We hypothesised that the all-out test CP would be significantly correlated with 16.1-km road time-trial (TT) performance and more strongly correlated with performance than the gas exchange threshold (GET), respiratory compensation point (RCP) and V?O2 max. Ten club-level male cyclists (mean±SD: age 33.8±8.2 y, body mass 73.8±4.3 kg, V?O2 max 60±4 ml·kg?1·min?1) performed a 10-mile road TT, a ramp incremental test to exhaustion, and two 3-min all-out tests, the first of which served as familiarisation. The 16.1-km TT performance (27.1±1.2 min) was significantly correlated with the CP (309±34 W; r=?0.83, P<0.01) and total work done during the all-out test (70.9±6.5 kJ; r=?0.86, P<0.01), the ramp incremental test peak power (433±30 W; r=?0.75, P<0.05) and the RCP (315±29 W; r=?0.68, P<0.05), but not with GET (151±32 W; r=?0.21) or the V?O2 max (4.41±0.25 L·min?1; r=?0.60). These data provide evidence for the predictive validity and practical performance relevance of the 3-min all-out test. The 3-min all-out test CP may represent a useful addition to the battery of tests employed by applied sport physiologists or coaches to track fitness and predict performance in atheletes.  相似文献   

7.
Various inflammation parameters are increased with childhood obesity, but few comparable data are found in lean growing athletes. This study aims to characterize differences in 12 simultaneously measured inflammatory parameters between pubertal rhythmic gymnasts (RG) and untrained controls (UC), and to examine the relationship between body composition and inflammatory markers. Sixty 10–12-year-old girls were divided into RG (n?=?30) and UC (n?=?30). Fat mass (FM) and fat free mass (FFM) were measured by dual-energy X-ray absorptiometry. Leptin and 12 inflammatory parameters (interleukin [IL]-2, IL-4, IL-6, IL-8, IL-10, vascular endothelial growth factor, interferon-gamma [IFN-γ], tumor necrosis factor-alpha, IL-1α, IL-1β, monocyte chemotactic protein-1 and epidermal growth factor) were measured from fasting blood samples. No differences were seen in 12 inflammatory markers between studied groups. As expected, leptin (RG: 2.4?±?1.1; UC: 7.6?±?4.2?ng?ml?1) and FM (RG: 7.3?±?2.3; UC: 11.8?±?5.1?kg) were lower (p?<?.05) in RG compared to UC. In the whole group of lean pubertal girls, 69.0% of the variability in body FM was determined by leptin, and 11.2% of the variability in body FFM was explained by IFN-γ. In conclusion, measured 12 inflammatory biomarkers were not different between RG and UC, despite lower leptin and FM in RG. In lean pubertal girls, IFN-γ was independently associated with FFM, and leptin with FM.  相似文献   

8.
ABSTRACT

Ultra-endurance athletes accumulate an energy deficit throughout their events and those competing in self-sufficient multi-stage races are particularly vulnerable due to load carriage considerations. Whilst urinary ketones have previously been noted in ultra-endurance exercise and attributed to insufficient carbohydrate (CHO) availability, not all studies have reported concomitant CHO intake. Our aim was to determine changes in blood glucose and β-hydroxybutyrate concentrations over five days (240 km) of a self-sufficient multi-stage ultramarathon in combination with quantification of energy and macronutrient intakes, estimated energy expenditure and evaluation of energy balance. Thirteen runners (8 male, 5 female, mean age 40 ± 8 years) participated in the study. Glucose and β-hydroxybutyrate were measured every day immediately post-running, and food diaries completed daily. CHO intakes of 301 ± 106 g·day?1 (4.3 ± 1.8 g·kg?1·day?1) were not sufficient to avoid ketosis (5-day mean β-hydroxybutyrate: 1.1 ± 0.6 mmol.L?1). Furthermore, ketosis was not attenuated even when CHO intake was high (9 g·kg?1·day?1). This suggests that competing in a state of ketosis may be inevitable during multi-stage events where load reduction is prioritised over energy provisions. Attenuating negative impacts associated with such a metabolic shift in athletes unaccustomed to CHO and energy restriction requires further exploration.  相似文献   

9.
Abstract

Low energy availability [(energy intake – exercise expenditure)/kg lean body mass], a component of the Female Athlete Triad, has been associated with menstrual disturbances and low bone mass. No studies have examined the energy availability of athletes across a season. The purpose of this study was to assess the prevalence of, and what contributes to, low energy availability in Division I female soccer players across a season. Nineteen participants aged 18–21 years (mean [Vdot]O2max: 57.0 ± 1.0 mL · kg?1 · min?1) were studied during the pre, mid, and post season. Mean energy availability was overall lowest at mid season, and lower at mid than post season (35.2 ± 3.7 vs. 44.5 ± 3.7 kcal · kg?1 lean body mass, P = 0.009). Low energy availability (<30 kcal · kg?1 lean body mass) was observed in 5/19 (26.3%), 5/15 (33.3%), and 2/17 (11.8%) of participants during the pre, mid, and post season. Dietary energy intake was lower mid (P = 0.008) and post season (P = 0.022) than it was pre season (pre: 2794 ± 233 kcal · day?1; mid: 2208 ± 156 kcal · day?1; post: 2161 ± 143 kcal · day?1). Exercise energy expenditure decreased significantly (P ≤ 0.001) over time (pre: 819 ± 57 kcal · day?1; mid: 642 ± 26 kcal · day?1; post: 159 ± 28 kcal · day?1). Low energy availability was due to lower dietary energy intake at lunch during pre season (P = 0.014) and during lunch and dinner during mid season (P ≤ 0.030). Energy availability was inversely related to body dissatisfaction (r = ?0.62, P = 0.017) and drive for thinness (r = ?0.55, P = 0.041) during mid season. Although most Division I female soccer players are not at risk for low energy availability, a concerning proportion exhibited low energy availability at pre or mid season. Further studies are needed to explore strategies to prevent and monitor low energy availability in these athletes.  相似文献   

10.
Abstract

Energy turnover was assessed in two conditions of mixed ultra-endurance exercise. In Study 1, energy expenditure and intake were measured in nine males in a laboratory over 24 h. In Study 2, energy expenditure was assessed in six males during an 800-km Adventure race (mean race time 152.5 h). Individual correlations between heart rate and oxygen uptake ([Vdot]O2) were established during pre-tests when kayaking, cycling, and running. During exercise, energy expenditure was estimated from continuous heart rate recordings. Heart rate and [Vdot]O2 were measured regularly during fixed cycling work rates to correct energy expenditure for drift in oxygen pulse. Mean energy expenditure was 18,050 ± 2,390 kcal (750 ± 100 kcal · h?1) and 80,000 ± 18,000 kcal (500 ± 100 kcal · h?1) in Study 1 and Study 2 respectively, which is higher than previously reported. Energy intake in Study 1 was 8,450 ± 1,160 kcal, resulting in an energy deficit of 9,590 ± 770 kcal. Body mass decreased in Study 1 (?2.3 ± 0.8 kg) but was unchanged in Study 2. Fat mass decreased in Study 2 (?2.3 ± 1.5 kg). In Study 1, muscle glycogen content decreased by only 60%. Adventure racing requires a high energy expenditure, with large inter-individual variation. A large energy deficit is caused by inadequate energy intake, possibly due to suppressed appetite and gastrointestinal problems. The oxygen pulse, comparing start to 12 h of exercise and beyond, increased by 10% and 5% in Study 1 and Study 2 respectively. Hence, estimations of energy expenditure from heart rate recordings should be corrected according to this drift.  相似文献   

11.
Abstract

Individuals with impaired glucose tolerance (IGT) are at greater risk of developing diabetes than in normoglycaemia. The aim of this study was to examine the effects of 12-weeks exercise training in obese humans with IGT. Eleven participants (6 males and 5 females; 49±9 years; mean Body Mass Index (BMI) 32.4 kg · m?2), completed a 12-week brisk walking intervention (30 min per day, five days a week (d · wk?1), at 65% of age-predicted maximal heart rate (HRmax). Anthropometric measurements, dietary intake, pulse wave velocity (PWV, to determine arterial stiffness) and blood pressure (BP) were examined at baseline and post intervention. Fasting blood glucose, glycosylated haemoglobin, insulin, blood lipids, indices of oxidative stress and inflammation (lipid hydroperoxides; superoxide dismutase; multimeric adiponectin concentration and high-sensitivity C-reactive protein) were also determined. Post intervention, PWV (9.08±1.27 m · s?1 vs. 8.39±1.21 m · s?1), systolic BP (145.4±14.5 vs. 135.8±14.9 mmHg), triglycerides (1.52±0.53 mmol . L?1 vs. 1.31±0.54 mmol . L?1), lipid hydroperoxides (1.20±0.47 μM · L?1 vs. 0.79±0.32 μM · L?1) and anthropometric measures decreased significantly (P < 0.05). Moderate intensity exercise training improves upper limb vascular function in obese humans with IGT, possibly by improving triglyceride metabolism, which may subsequently reduce oxidative stress. These changes were independent of multimeric adiponectin modification and alterations in other blood biomarkers.  相似文献   

12.
Abstract

Due to the unique energetic demands of professional young collision sport athletes, accurate assessment of energy balance is required. Consequently, this is the first study to simultaneously investigate the energy intake, expenditure and balance of professional young rugby league players across a pre-season period. The total energy expenditure of six professional young male rugby league players was measured via doubly labelled water over a fourteen-day assessment period. Resting metabolic rate was measured and physical activity level calculated. Dietary intake was reported via Snap-N-Send over a non-consecutive ten-day assessment period, alongside changes in fasted body mass and hydration status. Accordingly, energy balance was inferred. The mean (standard deviation) difference between total energy intake (16.73 (1.32) MJ.day?1) and total energy expenditure (18.36 (3.05) MJ.day?1) measured over the non-consecutive ten-day period was unclear (?1.63 (1.73) MJ.day?1; ES?=?0.91?±?1.28; p?=?0.221). This corresponded in a most likely trivial decrease in body mass (?0.65 (0.78) kg; ES?=?0.04?±?0.03; p?=?0.097). Resting metabolic rate and physical activity level across the fourteen-day pre-season period was 11.20 (2.16) MJ.day?1 and 1.7 (0.2), respectively. For the first time, this study utilises gold standard assessment techniques to elucidate the distinctly large energy expenditures of professional young rugby league players across a pre-season period, emphasising a requirement for equally large energy intakes to achieve targeted body mass and composition adaptations. Accordingly, it is imperative that practitioners regularly assess the energy balance of professional young collision-sport athletes to ensure their unique energetic requirements are achieved.  相似文献   

13.
Abstract

This study investigated the effects of acute caffeine ingestion following short-term creatine supplementation on an incremental cycling to exhaustion task. Twelve active males performed the task under three conditions: baseline condition (BASE, no ergogenic aid), creatine plus caffeine condition (CRE + CAF), and creatine with placebo condition (CRE + PLA). Following the establishment of BASE condition, participants were administered CRE + CAF (0.3 g·kg?1·day?1 of creatine for 5 days followed by 6 mg·kg?1 of caffeine 1 h prior to testing) and CRE + PLA (0.3 g·kg?1·day?1 of creatine for 5 days followed by 6 mg·kg?1 of placebo 1 h prior to testing) in a double-blind, randomized crossover and counterbalancing protocol. No significant differences were observed in relative maximal oxygen consumption ([Vdot]O2max) (51.7±5.5, 52.8±4.9 and 51.3±5.6 ml·kg?1·min?1 for BASE, CRE + CAF and CRE + PLA, respectively; P>0.05) and absolute [Vdot]O2max (3.6±0.4, 3.7±0.4 and 3.5±0.5 l·min?1 for BASE, CRE + CAF and CRE + PLA, respectively; P>0.05). Blood samples indicated significantly higher blood lactate and glucose concentrations in the CRE + CAF among those in the BASE or CRE + PLA condition during the test (P<0.05). The time to exhaustion on a cycling ergometer was significantly longer for CRE + CAF (1087.2±123.9 s) compared with BASE (1009.2±86.0 s) or CRE + PLA (1040.3±96.1 s). This study indicated that a single dose of caffeine following short-term creatine supplementation did not hinder the creatine–caffeine interaction. In fact, it lengthened the time to exhaustion during an incremental maximum exercise test. However, this regime might lead to the accumulation of lactate in the blood.  相似文献   

14.
ABSTRACT

The systematic review and meta-analysis evaluated the effect of aerobic, resistance and combined exercise on RMR (kCal·day-1) and performed a methodological assessment of indirect calorimetry protocols within the included studies. Subgroup analyses included energy/diet restriction and body composition changes. Randomized control trials (RCTs), quasi – RCTs and cohort trials featuring a physical activity intervention of any form and duration excluding single exercise bouts were included. Participant exclusions included medical conditions impacting upon RMR, the elderly (≥65 years of age) or pregnant, lactating or post-menopausal women. The review was registered in the International Prospective Register of Systematic Reviews (CRD 42,017,058,503). 1669 articles were identified; 22 were included in the qualitative analysis and 18 were meta-analysed. Exercise interventions (aerobic and resistance exercise combined) did not increase resting metabolic rate (mean difference (MD): 74.6 kCal·day-1[95% CI: ?13.01, 161.33], P = 0.10). While there was no effect of aerobic exercise on RMR (MD: 81.65 kCal·day-1[95% CI: ?57.81, 221.10], P = 0.25), resistance exercise increased RMR compared to controls (MD: 96.17 kCal·day-1[95% CI: 45.17, 147.16], P = 0.0002). This systematic review effectively synthesises the effect of exercise interventions on RMR in comparison to controls; despite heterogenous methodologies and high risk of bias within included studies.  相似文献   

15.
Abstract

The aim of this study was to examine how running experience affects leg stiffness (Kleg) and spring-mass characteristics during running stages associated with the onset of blood lactate accumulation (OBLA). Seven trained (66.9?±?4.8?kg; 182?±?4.0?cm; 23.1?±?3.1 years) and 13 untrained (78.5?±?7.6?kg; 182?±?3.0?cm; 20.3?±?1.5 years) runners completed an incremental treadmill run. Running velocity was increased by 1 km.h?1 every four minutes and blood lactate samples were taken at every stage, in addition to a 10?s video recording using ‘Runmatic’. Once 4?mmol?L?1 (OBLA; the second lactate turn point) had been reached one more stage was completed. Spring-mass characteristics across groups and at pre-OBLA, OBLA and post-OBLA were compared. The velocity at OBLA was higher for the trained runners compared to the untrained runners (18?±?0.7 vs 11?±?1.3 km.h?1, p?<?0.001). Kleg was similar between untrained and trained runners across each stage (15.8?±?0.3 vs 14.3?±?0.3 kN.m) and did not change between stages, yet spring-mass characteristics differed between groups. Vertical stiffness increased in the trained runners from pre-OBLA to post-OBLA (45.5?±?3.35–51.9?±?3.61 kN?1), but not in untrained runners (35.0?±?5.2–39.6?±?5.7 kN?1). Kleg was strongly related to Fpeak for trained runners only (r?=?0.79; untrained runners, r?=?0.34). Kleg was unaffected by physiological training status and was maintained across all OBLA stages. Trained runners appear to have optimised their spring-mass system in a homogenous manner, whilst less consistent spring-mass characteristics were observed in untrained runners.  相似文献   

16.
ABSTRACT

Fat-free mass index (FFMI) is a height-adjusted metric of fat-free mass which has been suggested as a useful method of body composition assessment in athletic populations. The purpose of this study was to determine sport-specific FFMI values and the natural upper threshold of FFMI in female athletes. 372 female collegiate athletes (Mean±SD; 20.03±1.55 years, 167.55±7.50 cm, 69.46±13.04 kg, 24.18±5.48% bodyfat) underwent body composition assessment via dual-energy x-ray absorptiometry. FFMI was adjusted to height via linear regression and sport-specific reference values were determined. Between-sport differences were identified using one-way ANOVA with Tukey post-hoc tests. Average FFMI was 18.82±2.08 kg/m2; height-adjusted values were not significantly different (p<0.05) than unadjusted values. FFMI in rugby athletes (20.09±2.23 kg/m2) was found to be significantly higher (p<0.05) than in gymnastics (18.62±1.12 kg/m2), ice hockey (17.96±1.04 kg/m2), lacrosse (18.58±1.84 kg/m2), swim & dive (18.16±1.67 kg/m2), and volleyball (18.04±1.13 kg/m2). FFMI in cross country (16.56±1.14 kg/m2) and synchronized swimming (17.27±1.47 kg/m2) was significantly lower (p<0.05) than in Olympic weightlifting (19.69±1.98 kg/m2), wrestling (19.15±2.47 kg/m2), and rugby. The upper threshold for FFMI in female athletes (97.5th percentile) was 23.90 kg/m2. These results can be used to guide personnel decisions and assist with long-term body composition, training, and nutritional goals.  相似文献   

17.
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18.
Abstract

This study was designed to investigate the effect of ingesting a glucose plus fructose solution on the metabolic responses to soccer-specific exercise in the heat and the impact on subsequent exercise capacity. Eleven male soccer players performed a 90 min soccer-specific protocol on three occasions. Either 3 ml · kg?1 body mass of a solution containing glucose (1 g · min?1 glucose) (GLU), or glucose (0.66 g · min?1) plus fructose (0.33 g · min?1) (MIX) or placebo (PLA) was consumed every 15 minutes. Respiratory measures were undertaken at 15-min intervals, blood samples were drawn at rest, half-time and on completion of the protocol, and muscle glycogen concentration was assessed pre- and post-exercise. Following the soccer-specific protocol the Cunningham and Faulkner test was performed. No significant differences in post-exercise muscle glycogen concentration (PLA, 62.99 ± 8.39 mmol · kg wet weight?1; GLU 68.62 ± 2.70; mmol · kg wet weight?1 and MIX 76.63 ± 6.92 mmol · kg wet weight?1) or exercise capacity (PLA, 73.62 ± 8.61 s; GLU, 77.11 ± 7.17 s; MIX, 83.04 ± 9.65 s) were observed between treatments (P > 0.05). However, total carbohydrate oxidation was significantly increased during MIX compared with PLA (P < 0.05). These results suggest that when ingested in moderate amounts, the type of carbohydrate does not influence metabolism during soccer-specific intermittent exercise or affect performance capacity after exercise in the heat.  相似文献   

19.
Professional soccer players from the first team (1st team, n = 27), under twenty-one (U21, n = 21) and under eighteen (U18, n = 35) squads of an English Premier League soccer team were assessed for whole body and regional estimates of body composition using dual-energy X-ray absorptiometry (DXA). Per cent body fat was lower in 1st team (10.0 ± 1.6) compared with both U21 (11.6 ± 2.5, P = 0.02) and U18 (11.4 ± 2.6, P = 0.01) players. However, this difference was not due to variations (P = 0.23) in fat mass between squads (7.8 ± 1.6 v 8.8 ± 2.1 v 8.2 ± 2.4 kg, respectively) but rather the presence of more lean mass in 1st team (66.9 ± 7.1 kg, P < 0.01) and U21 (64.6 ± 6.5 kg, P = 0.02) compared with U18 (60.6 ± 6.3 kg) players. Accordingly, fat mass index was not different (P = 0.138) between squads, whereas lean mass index was greater (P < 0.01) in 1st team players (20.0 ± 1.1 kg · m?2) compared with U18 players (18.8 ± 1.4 kg · m?2). Differences in lean mass were also reflective of higher lean tissue mass in all regions, for example, upper limbs/lower limbs and trunk. Data suggest that training and nutritional interventions for younger players should therefore be targeted to lean mass growth as opposed to body fat loss.  相似文献   

20.
This prospective study determined whether: (1) objective physical activity (PA) and sedentary (SED) time at 9 years was associated with cognition at 15 years, (2) cognition at 9 years was associated with PA and SED at 15 years, and (3) the change in PA and SED from 9 to 15 years was associated with the change in cognition. Cognitive performance was assessed from picture vocabulary, verbal analogy, passage comprehension, and applied problem tasks. Regression models were used to explore each aim while adjusting for covariates. Among the combined sample, SED (min· day?1) at 9 years was unrelated with cognitive performance at 15 years, whereas participating in ≥ 60 min· day?1 of moderate-to-vigorous PA (MVPA) at 9 years predicted lower cognitive scores at 15 years. In the reverse direction, cognitive performance at 9 years was unrelated with SED and MVPA (min· day?1) at 15 years. Over 6 years, increased SED (min· day?1) predicted lower improvement to verbal analogy scores (B = ?0.01, p = 0.028). In comparison, an increase (or relatively smaller decline) in MVPA (min· day?1) predicted greater improvement in applied problem scores (B = 0.06, p = 0.007). Contextual information regarding SED and MVPA behavior would help understand bi-directional associations of activity and cognition.  相似文献   

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