乳腺癌患者保留肋间臂神经的临床意义     

李洪涛  赵凯  李媛媛  王金科  信国峰 《河北北方学院学报(医学版)》2006,23(2):9-12

目的：探讨乳腺癌腋窝淋巴结清扫术保留肋间臂神经的价值。方法：对天津医科大学附属肿瘤医院2000．1-2001．12月间69例保留肋间臂神经和34例切除肋间臂神经的乳腺癌患者进行随访。结果：肋间臂神经保留组术后48例无感觉方面上的变化，11例发生感觉麻木，1例上肢出现烧灼感，9例上肢出现感觉减退；而肋间臂神经切除组术后3例出现腋窝无汗．18例发生感觉麻木，4例上肢出现烧灼感，9例上肢出现感觉减退。两组之间在统计学上有显著性差异（x^2=48．1570；P〈0．05）；肋间臂神经保留组58例术后未发生患肢疼痛，11例发生患肢疼痛；而肋问臂神经切除组5例术后未发生患肢疼痛，29例术后发生患肢疼痛。两组患者之间在统计学上有显著性差异（x^2=46．1194；P〈0．05）。结论：乳腺癌患者保留肋间臂神经可以明显减少术后患侧上肢感觉障碍和疼痛的发生，从而提高患者的生活质量。  相似文献   

Surgical management of gastric stump cancer： a report of 37 cases   总被引：3，自引：0，他引：3  

Chen L  Tian H  Chen J  He ZG  Tao SF  Lokesh G  Peng SY 《Journal of Zhejiang University. Science. B》2005,6(1):38-42

Objective: To observe the clinicopathological characteristics of gastric stump cancer (GSC) and evaluate the benefits of radical surgery of GSC. Methods: The clinicopathological characteristics and postoperative survival time of 37 GSC patients who underwent surgery were investigated retrospectively. The survival time was compared according to the type of surgical pTMN stage. Survival curves were traced by using Kaplan-Meier methods. Results: Most GSC (32/37) was detected in patients who had received Billroth Ⅱ reconstruction after partial gastrectomy for benign gastric disease. The lesser curvature side and the suture line of anastomosis were the most frequent sites where GSC occurred (27/37). Differentiated adenocarcinoma was the dominant histopathological type (24/37). The postoperative 5-year survival rate of early stage GSC patients (n=9) was significantly higher than advanced stage GSC (n=12) (55.6% vs 16.5%, xL2=1 1.48, P＜0.01). Five-year survival rate of 21 GSC patients with radical resection were 75% (3/4) for stage Ⅰ, 60% (3/5) for stage Ⅱ, 14.2% (1/7) for stage Ⅲ, and 0% (0/5) for stage Ⅳ respectively.The median survival time of 21 GSC patients who underwent radical resection was longer than those undergoing palliative operation (43.0m vs 13.0m, xL2=36.31, P＜0.01), the median survival time of stage Ⅳ patients with radical resection was 23.8months. Conclusions: Without remote metastasis, radical resection for GSC is possible, and is an effective way to improve the prognosis of GSC. Even in stage Ⅳ GSC, radical resection can still prolong the survival time. It is necessary for the patients with benign gastric diseases who received partial gastrectomy to carry out the endoscopy follow-up, especially in patients with Billroth Ⅱ reconstruction procedure at 15-20 years.  相似文献   

Study on interleukin-18 gene transfer into human breast cancer cells to prevent tumorigenicity   总被引：1，自引：0，他引：1  

韩明勇  郑树  于金明  彭佳萍  郭其森  王家林 《Journal of Zhejiang University. Science. B》2004,(4)

INTRODUCTIONInterleukin-18(IL-18),originallydescribedasinterferon(IFN)-g-inducingfactor,isan18.3-kDaproinflammatorycytokineproducedbyactivatedmacrophagesanddendriticcells,andplaysanim-portantroleintheTh1response,primarilybasedonitsabilitytoinduceIFN-gproductioninTcellsandNKcells.IL-18inducesproliferationofactivatedTcells,secretionofseveralcytokines,andpartici-patesinbothinnateandacquiredimmunity.TheroleofIL-18inantitumorimmunitywassuggestedinmanystudies.Genetransferofcytokinesisani…  相似文献   

Review: Video-assisted thoracic surgery--the past, present status and the future     

LUH Shi-ping  LIU Hui-ping 《Journal of Zhejiang University. Science. B》2006,7(2)

  相似文献   

Survivin在乳腺癌及大肠癌中表达的临床意义     

张秀昌  张杰  薄爱华  张晓丽  孙黎 《河北北方学院学报(医学版)》2007,24(3):9-11

目的：探讨大肠癌、乳腺癌中生存素的临床意义。方法：收集大肠癌68例,乳腺癌69例,利用SABC免疫组织化学方法,检测Survivin表达状况。结果：大肠癌和乳腺癌中Survivin阳性率分别为63.24%和42.03%,Survivin在大肠癌低分化组和深浸润组阳性率明显高于浅浸润和高分化组;在浸润型乳腺癌组和有淋巴结转移组Survivin阳性率明显增高。结论：Survivin表达与癌组织生物学特性有关;检测癌组织中Sur-vivin表达可以提示预后及指导靶向治疗方案的制定。  相似文献   

肺内孤立性结节的HRCT扫描与病理相关研究     

崔书君  康燕华  刘昭 《河北北方学院学报(医学版)》2006,23(6):5-8

目的：探讨肺内孤立性结节（Solitary pulmonary nodule．SPN）的HRCT特征与良恶性病变之间的关系。方法：对66例肺内孤立性结节病灶进行螺旋HRCT增强扫描，观察结节增强的程度、周围的血管以及瘤肺界面的特征，来判定结节的良恶性。结果：病理证实50例周围型肺癌（Peripheral lung cancer，PLC）．16例良性结节。①PLC血供较良性结节丰富；②动脉期结节强化程度增强明显，平衡期达到峰值为PLC，PLC瘤肺界面清晰伴有深分叶，良性结节周围模糊。结论：PLC血供丰富、增强快，平衡期达最高，瘤肺界面清晰；良性结节增强慢，与肺界面关系模糊。  相似文献   

支气管肺癌并发肺脓肿48例临床分析   总被引：4，自引：0，他引：4  

支学军  王蕾 《河北北方学院学报(医学版)》2005,22(1):53-54

目的:探讨支气管肺癌并发肺脓肿的诊断.方法:回顾分析48例支气管肺癌并发性肺脓肿的临床、放射、纤维气管镜检查及开胸肺活检方面的资料.结果:肺癌合并肺脓肿时思维要开阔,纤支镜或开胸肺活检可协助肺癌确诊.结论:纤支镜对肺脓肿、肺癌明确诊断帮助很大,可减少误诊机会.  相似文献   

Distribution of H.pylori antigens in gastric mucosa and its significance   总被引：2，自引：0，他引：2  

陆新良  钱可大  唐训球  朱永良 《Journal of Zhejiang University. Science. B》2004,(2)

INTRODUCTION Helicobacter pylori (H.pylori) was grouped as a class I carcinogen by the International Agency for Research on Cancer in 1994. A direct relation be-tween H.pylori infection and gastric carcinogenesis was demonstrated in 1998 in an experimental animal model (Watanabe et al., 1998). However, the role of H.pylori in human gastric carcinogenesis is sup-ported almost exclusively by epidemiological data and prospective histopathological studies. So far the mechanism of H.pylor…  相似文献   

关于膳食纤维抗大肠癌的研究   总被引：5，自引：0，他引：5  

刘金香  熊友爱 《江西教育学院学报》2003,24(3):37-39

科学家和医生们对食物纤维与结肠癌风险之间的关系，已进行了20多年的研究，取得了许多研究成果，但也存在着一些争论。本文介绍了国外对此问题的研究方向、研究方法及其进展情况。  相似文献   

艾迪加体部伽玛刀治疗非小细胞肺癌疗效观察     

钱永红  孙小东  赵琦 《雁北师范学院学报》2007,23(2):73-75

为了观察艾迪加体部伽玛刀治疗非小细胞肺癌的近期疗效及毒副反应,经临床、影像学和病理学诊断90例非小细胞肺癌,采用随机分组原则分为艾迪加体部伽玛刀治疗组和单纯体部伽玛刀治疗组.结果表明,治疗后3个月复查艾迪加体部伽玛刀治疗组总有效率和CR均略高于单纯体部伽玛刀治疗组;治疗后白细胞下降率分别为4.44%和17.78%,症状改善率分别为84.44%和62.22%,KPS提高率分别为62.22%和33.33%,组间差异性明显.可见,艾迪加体部伽玛刀治疗既能提高非小细胞肺癌的局部控制率,又能增强机体免疫功能.  相似文献