模拟梯度交替海拔低氧训练对大鼠骨骼肌相关代谢的影响     

刘金柱 《德州学院学报》2012,28(4):45-48

应用人工低压氧舱模拟高原训练的方法,建立梯度交替海拔的动物训练模型,下高原调整后以45m/min的速度快速力竭,紫外分光光度法测定固定海拔2500m、4000m以及2500m～4000m交替训练模式大鼠骨骼肌匀浆液中肌糖原、SOD、MDA、LDH、ATP指标变化,为运动员高原训练后平原快速运动参赛提供参考.  相似文献   

模拟低氧训练对大鼠红细胞流变性的影响     

杜美珍 《忻州师范学院学报》2012,28(2):119-121

目的:旨在观察2800m海拨高度的训练对大鼠血红蛋白及红细胞流变性的影响。方法:采用SD(Sprague-Dewley)大鼠40只,随机将其分为常氧常压组(LN),常氧常压训练组(LNT),低氧低压组(LH),低氧低压训练组(LHT)。LN、LNT组和LH、LHT分别置于正常海拔高度与相当于2800m的生活条件下,其训练环境同生活环境保持一致。LNT和LHT组分别在所控制的环境中,进行为期五周的训练。每周训练五天。结果:发现五周的低氧刺激或低氧训练,LH和LHT组的血红蛋白含量、红细胞压积和红细胞变形能力均显著升高(P<0.05),但LN和LNT组未发生显著变化。结论:五周的低氧刺激或低氧训练,均能提高大鼠机体内的血红蛋白含量、红细胞压积和红细胞变形能力,低氧刺激与低氧结合训练刺激所产生的效果并没有显著性差异。  相似文献   

模拟高住低训对女子长跑运动员运动能力的影响   总被引：1，自引：0，他引：1  

王晓红  魏永  潘华山  熊卫权  毛书凯 《首都体育学院学报》2008,20(5)

模拟高原训练方法之一的低氧屋有其独特的运动训练功能。通过观察用低氧屋间歇性常压低氧居住对女子长跑运动员的运动能力的影响。结果发现:长期间歇性低氧居住可以使女子长跑运动员的耐力提高获得像高原训练的效果,从一定程度来讲是低氧居住刺激RBC、Hob产生,血液携氧能力增加,最大摄氧量提高所致。  相似文献   

高住低训抑制大鼠骨骼肌mTOR蛋白表达   总被引：1，自引：1，他引：0  

贺道远  曾凡星  王伟明 《北京体育大学学报》2008,31(8)

目的:探讨运动和低氧影响骨骼肌生长的分子调控机制。方法:SD大鼠分为6组:1)28 d组,包括对照组、常氧运动组、低氧暴露组、高住低训组;2)复氧7 d组,包括低氧暴露复氧7 d组、高住低训复氧7 d组,每组6只。常氧运动组进行4周的跑台运动。低氧暴露组白天与对照组在常氧下生活,晚上在氧浓度13.6%低氧舱内低氧暴露12 h;复氧7 d组进行低氧暴露后复氧7 d。高住低训组每天运动后1 h进行低氧暴露。实验后取腓肠肌称重,采用western blot测定mTOR蛋白表达。结果:1)28 d常氧运动后骨骼肌mTOR蛋白表达明显上降(p<0.05);2)28 d高住低训后骨骼肌mTOR蛋白表达明显下降(p<0.05),复氧7 d后显著回升(p<0.05)。结论:运动和低氧调节骨骼肌mTOR蛋白表达,提示高住低训抑制骨骼肌生长可能与运动、低氧调控骨骼肌mTOR信号并影响蛋白翻译过程有关。  相似文献   

跨文化视角下我国留学生适应辅助项目的发展     

孟蕾 《世界教育信息》2007,(6):75-78

留学生脱离自身文化母体的浸润,进入新的社会文化中生活,会遇到语言和生活习惯等方面的适应问题。研究表明,留学生辅助项目能够帮助学生缩短文化适应期,减弱甚至克服文化冲击带来的各种不适。目前,我国高校已开展了此类适应辅助项目,但与留学大国相比还有很大的发展空间。  相似文献   

Mechanisms underlying reductions in stroke volume at rest and during exercise at high altitude     

Mike Stembridge  Philip N. Ainslie  Rob Shave 《European Journal of Sport Science》2016,16(5):577-584

High-altitude exposure challenges the cardiovascular system to maintain oxygen delivery to the mitochondria under conditions of hypoxic stress. Following acclimatisation (3–5 days), stroke volume (SV) falls to below sea-level values but heart rate remains elevated, such that cardiac output is maintained compared to sea level. The decrease in SV has been a topic of research for over 40 years, but the underlying mechanisms are incompletely understood. Impaired systolic contractile function secondary to reduced coronary arterial oxygen tension has been investigated as a potential cause for the decrease in SV. However, despite in vitro evidence of impaired cardiac contractile force in severe hypoxia, the majority of studies to date have reported enhanced in vivo ventricular systolic function at rest and during exercise in humans up to and above 5000?m. However, the elevated function observed at rest has recently been suggested to reduce the functional reserve available during exercise. While in vivo systolic function appears enhanced at high altitude, a decrease in left ventricular end-diastolic volume (EDV) and altered filling patterns of both ventricles has been observed. The reduction in ventricular filling will undoubtedly affect SV, and four potential mechanisms have been proposed to explain the reduction in left ventricular filling. In this article, both historical and recent reports of systolic function at high altitude will be reviewed, and evidence supporting and refuting each of the four mechanisms underpinning reduced left ventricular filling will be discussed.  相似文献   

不同海拔高度低氧暴露及运动对大鼠氧传递能力的影响     

杜霞  藤井久雄  苏青青  马延峰  马福海 《福建体育科技》2016,(4):24-27

对大鼠采用不同海拔及组合模式的低氧暴露和运动方法,通过红细胞等指标探讨不同海拔高度下的低氧适应和机体氧传递能力。方法：9周龄wistar雄性大鼠80只（体重269.38±6.24g）,分为非运动组和运动组两大组。每组分为0m、2200m、2200＋3500m、3500m共4组,每小组10只。其中运动组大鼠每天在时速设定为20－22m／mim、坡度0°的跑台上训练90分钟,每周5天共6周。结果：3500m及以下的4种不同海拔高度下无论是低氧暴露还是运动,红系细胞RBC、 Hb、 Hct均表现随海拔的升高而升高,而运动组的升高幅度更为显著,同时2200＋3500m组合式模式无论是运动组还是非运动组均出现了最高峰值。结论：在不同海拔环境下低氧是影响血细胞升高的重要因素,但低氧环境下复合运动负荷更能促进血细胞RBC、 Hb、 Hct生成,且2200＋3500 m组合式模式更能有效的促进红系细胞生成量,从而更有利于提高机体氧传递能力和有氧能力。  相似文献   

低氧减肥的研究及应用     

邓潇潇  吴红豫 《福建体育科技》2016,(2)

采用综述的方法,分析了低氧运动减肥的科学性,以及低氧在大众健康促进中的应用,得出主要结论：多数低氧暴露结合中等强度有氧运动对于脂肪代谢有积极作用,在降低体重的同时可能有利于身体成分的良好改变,提高身体健康程度,低氧对于大众健康的促进也有一定意义。建议：后续研究应提出针对青少年的个性化训练方案,例如结合个体最大脂肪代谢率等;未来应进一步确认是否低氧训练可作为一种新的减体重同时治疗肥胖相关疾病的手段,并阐明潜在机制。  相似文献   

低氧、运动对大鼠腓肠肌血管内皮细胞生长因子表达的影响   总被引：2，自引：0，他引：2  

王维群  陆彩凤  姜文凯  雷涛  潘菊芳 《西安体育学院学报》2008,25(6)

选用健康雄性SD大鼠144只，采用ELISA法，研究短期低氧、不同强度常氧运动和高住低练对大鼠腓肠肌VEGF表达的影响。结果表明，低氧和常氧运动诱导的骨骼肌VEGF表达属早期效应，长时间中等强度的运动比间歇性的高强度运动诱导更多的VEGF表达，高住低练削弱了长时间中等强度运动诱导的VEGF表达。  相似文献   

Altitude training in endurance running: perceptions of elite athletes and support staff     

Gareth Turner  Barry W Fudge  Jamie S M Pringle  Neil S Maxwell  Alan J Richardson 《Journal of sports sciences》2019,37(2):163-172

This study sought to establish perceptions of elite endurance athletes on the role and worth of altitude training. Elite British endurance runners were surveyed to identify the altitude and hypoxic training methods utilised, along with reasons for use, and any situational, cultural and behaviour factors influencing these. Prior to the 2012 Olympics Games, 39 athletes and 20 support staff (coaches/practitioners) completed an internet-based survey to establish differences between current practices and the accepted “best-practice”. Almost all of the athletes (98%) and support staff (95%) surveyed had utilised altitude and hypoxic training, or had advised it to athletes. 75% of athletes believed altitude and hypoxia to be a “very important” factor in their training regime, with 50% of support staff believing the same. Athletes and support staff were in agreement of the methods of altitude training utilised (i.e. 'hypoxic dose’ and strategy), with camps lasting 3–4 weeks at 1,500–2,500 m being the most popular. Athletes and support staff are utilising altitude and hypoxic training methods in a manner agreeing with research-based suggestions. The survey identified a number of specific challenges and priorities, which could provide scope to optimise future altitude training methods for endurance performance in these elite groups.  相似文献