共查询到20条相似文献，搜索用时 31 毫秒
1.
D. C. Sharma Bhawani Kochar Ankita Bhardwaj Manminder Riyat Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2009,24(3):245-249
In order to scientifically evaluate the effect of copper bhasm, it was orally administered in a dose of 2 mg/day for seven
days to one month old male chicks. There was significant fall in total red cells, and rise in plasma iron, PCV and MCV indicating
hemolysis, compensated by increased heme synthesis. A significant increase in plasma iron binding capacity points to beneficial
effect of copper bhasm on liver as transferrin is synthesized in liver. Ferritin (storage iron) was unaltered in seven days
treatment. The effect of copper bhasm on tissue distribution of essential elements was variable. Calcium, sodium and potassium
were significantly increased in all the tissues. The last two may have been contributed by the bhasm itself. Magnesium behaviour
was similar to calcium. Iron and zinc showed variable effects. Copper level in whole blood, plasma and erythrocytes increased
significantly showing that copper bhasm was well absorbed and the effect observed can be ascribed to it. The bhasm was well
tolerated and no growth retardation was seen. 相似文献
2.
I. Mazumdar K. Goswami Md Suhrab Ali 《Indian journal of clinical biochemistry : IJCB》2017,32(1):110-116
Jewelry utilizes lead either directly or as a base metal. Costume jewelry requires lead before molding and plating the product with valuable metals. Therefore, such ornaments have a great potential to release heavy metals having health hazards. Also, jewelry makers engaged in preparing German silver, an alloy, apply lead in smelting, alloying, rolling and milling silver wires and pieces. The metal is taken up by blood, soft tissues and bone. The biological effects of lead are dependent upon the level and duration of exposure. Lead inhibits three enzymes of heme biosynthesis- δ-amino-levulinic-acid dehydratase (ALAD), coproporphyrin oxidase, and ferrochelatase, impairing heme synthesis and depressing serum level of erythropoietin resulting in decreased hemoglobin synthesis. Lead exposure also affects calcium metabolism and impair the synthesis of Calcitriol. In the present study, jewelry makers from Dhaka, Bangladesh, were shown to have significantly high levels of lead, protein, albumin, and parathormone in their blood, and significantly high amount of zinc-protoporphyrin and δ-amino-levulinic-acid in their urine. The control group, on the other hand showed significantly higher amounts of calcium (both total and ionized form) Vitamin D3 and non-activated erythrocyte ALAD in their blood, along with hemoglobin. It might be due to inhibition of 1-α-hydroxylase enzyme in renal tubules. Lead causes nephro-toxicity and inhibits 1-α- hydroxylase enzyme leading to decreased calcitriol synthesis resulting in impaired calcium absorption across gastro-intestinal tract and renal tubules. Low Vitamin D3 and significantly increased Parathyroid hormone (PTH) in study group has been found. 相似文献
3.
4.
CO2浓度升高对植物种子萌发及叶片的影响 总被引：1，自引：0，他引：1
利用OTC－1型开顶式室进行了CO2浓度对植物种子发芽率、发芽势以及叶片形态结构的影响试验研究。结果表明：CO2浓度升高对发芽率影响不大,但发芽势明显增设,CO2浓度有加速种子萌发的作用。CO2浓度升高对C3作物叶面积、叶干物重增加显著,C4作物增加不明显;随着CO2浓度升高,C3作物叶片气孔密度变小,C4作物（玉米）呈相反趋势;水分胁迫使气孔密度增加;CO2浓度升高,气孔阻力增大,蒸腾速率下降。 相似文献
5.
烟雾吸入伤早期氧化与抗氧化动态平衡变化的实验研究 总被引：1，自引：0，他引：1
采用大鼠烟雾吸入伤模型，动态观察了伤后血浆、支气管肺泡灌洗液（ＢＡＬＦ）和肺组织中超氧化物歧化酶（ＳＯＤ）活性、丙二醛（ＭＤＡ）和共轭二烯（ＣＤ）含量的变化，辅以动脉血气分析、肺水量测定、ＢＡＬＦ中白细胞分类计数和病理检查．结果发现，伤后动物出现急性呼吸衰竭和严重肺水肿，肺内大量炎细胞聚集浸润；血浆、ＢＡＬＦ及肺组织中ＳＯＤ活性明显降低，ＣＤ和ＭＤＡ含量显著增加，ＭＤＡ／ＳＯＤ比值亦明显增高，且与ＢＡＬＦ中中性粒细胞数增加显著相关，提示氧化与抗氧化平衡失调可能在急性烟雾吸入性肺损伤的发生发展中起重要作用 相似文献
6.
Al-Orf SM 《Indian journal of clinical biochemistry : IJCB》2011,26(2):154-160
In this study it was planned to investigate the effect of oxidized phosphatidylcholine (derived from egg) feeding on lipid
peroxidation of different tissues in rats. Male Wistar albino rats were fed oxidized and unoxidized phosphatidylcholine for
2 and 4 weeks, respectively. During the period of study food intake and body weights of animals increased gradually. Animals
fed oxidized phosphatidylcholine for 2 and 4 weeks showed 33 and 15% spontaneous hemolysis of red blood cells in vitro. Under
identical experimental conditions animals given unoxidized phosphatidylcholine showed 14.5 and 13.4% hemolysis for 2 and 4
week’s period, respectively. Thiobarbituric acid reactive substances (TBARS) level in thymus, spleen, kidney, heart, liver
and lung significantly increased in rats given oxidized phosphatidylcholine as compared to unoxidized group. Furthermore,
in oxidized phosphatidylcholine group TBARS values in kidney, liver and lungs continued to rise for 4 weeks of treatment while
TBARS level in heart, spleen and thymus was found to be decreased at the end of 4 weeks of oxidized phosphatidylcholine feeding.
Plasma triacylglycerol and cholesterol was found to increase in rats who had received oxidized phosphatidylcholine for 2 weeks.
These findings suggest that excess and persistent intake of oxidized phosphatidylcholine can cause significant damage to organs. 相似文献
7.
水稻生长对气温变化响应的研究——以江苏姜堰市不同播种期试验为例 总被引：2，自引：1，他引：1
以中熟中粳徐稻3号为试验品种,研究气温升高对苏南地区(江苏姜堰市)水稻生长的影响。通过文献阅读获取当地播期试验数据,与同期气象数据相结合,构建水稻增温试验,模拟研究气候变化对水稻生长的影响。结果表明,气温升高有利于苏南地区的水稻生长。各生理指标受升温影响的具体表现为:水稻生育期缩短,尤其是营养生长时期;叶面积指数(LAI)增量在播种至拔节期及拔节至抽穗期增加,抽穗至成熟期减小,升温有利于水稻生长前期的叶片增长,同时也会加快后期的叶片衰亡;光合势(LAD)在播种至拔节期及拔节至抽穗期下降,而抽穗至成熟期增加;水稻生长各个时期的干物质(DMA)累积增量与群体生长率(CGR)均增加。分析表明,拔节至抽穗期与抽穗至成熟期出现气温饱和点,分别为27.5℃与23℃,均在最适温度范围内。 相似文献
8.
S. Mohanty P. K. Sahu M. K. Mandal P. C. Mohapatra A. Panda 《Indian journal of clinical biochemistry : IJCB》2006,21(1):101-105
This work was undertaken to investigate correlation between oxidative stress and initiation of pathogenesis of pregnancy induced
hypertension (PIH). Fifty primigravidae in age group of 20–35 years and gestational age 28–42 weeks with PIH were taken as
cases. Twenty healthy primigravidae with no medical and surgical complications of pregnancy and with blood pressure ≤140/90
mm Hg served as controls. The cases were again subgrouped as severe preeclampsia (12 in number) and mild pre-eclampsia (38
in number). All of them were evaluated for serum malondialdehyde (MDA), Serum vitamin E and plasma vitamin C levels. The serum
MDA levels were raised significantly in women with mild preeclampsia (P<0.01) and in women with severe preeclampsia (P<0.01)
in comparison to normal primi gravida. The serum vitamin E levels were decreased in primi gravida with mild preeclampsia (p<0.1)
and in primi with severe pre eclampsia (P<0.1) in comparison to normal primi gravida but the fall was not statistically significant.
There was a significant fall (P<0.05) in the vitamin C levels in primi with mild preeclampsia than in the normal primi. The
vitamin C levels in severe preeclamptic patients were lower than the normal primi but the fall was not statistically significant
(P=0.10). The serum MDA and vitamin E showed a negative correlation in all the cases. The serum MDA and plasma vitamin C also
showed a negative correlation in the control and study group. This observation suggests that in hypertensive disorders of
pregnancy there is an imbalance between lipid peroxidation and antioxidant vitamin status because of oxidative stress. The
decreased serum concentrations of the antioxidant vitamins supports the hypothesis that lipid peroxidation is an important
causative factor in the pathogenesis of preeclampsia. The rise in antioxidants is probably to compensate the increased peroxide
load in severe preeclampsia. 相似文献
9.
Shashi Seth Bina Ravi H. S. Randhawa Neelam Chillar Harbans Lal 《Indian journal of clinical biochemistry : IJCB》1996,11(1):49-51
Gamma-glutamyl transpeptidase (gamma-GT) levels were estimated in the sera of patients with breast cancer and compared with those of benign breast diseases and healthy controls. Serum gamma-GT levels were found to be significantly increased in patients with breast cancer compared to the controls as well as benign breast diseases. The rise however, was nearly same in all the patients irrespective of histopathology of cancer but was directly related to tumour mass. After mastectomy the levels remained higher upto 3 months. In patients with cancer the rise in serum gamma-GT was significantly higher as compared to those with benign breast diseases. Although gamma-GT is an index of liver diseases, its high level in breast carcinoma suggests the release of the membrane bound constituents from different tissues even in carcinoma. 相似文献
10.
盆栽实验条件下,研究了种植在两种土壤基质的豆科草本植物鸡眼草(Kummerowia striata)对水分胁迫和丛枝菌根真菌的响应。水分处理为对照(土壤相对含水量为70%~80%)和中度干旱胁迫(土壤相对含水量为45%~55%),菌根真菌处理为接种和不接种处理。结果表明,水分和基质均影响菌根真菌的侵染率,水分胁迫降低侵染率,条件较好的基质1菌根真菌的侵染率明显高于条件较差的基质2。两种基质条件下,接种菌根真菌都显著降低叶片丙二醛含量(P<0.05)但提高了可溶性糖含量、增加了鸡眼草的分枝数和提高了鸡眼草的地上部分和地下部分生物量。干旱胁迫处理,基质1下菌根真菌提高植物抗旱性的效果为4.29%,而基质2下菌根真菌提高植物抗旱性的效果为11.29%。 相似文献
11.
为了解和掌握叶片处理段工艺参数与切丝含水率的相关关系,采用一元线性回归分析方法对叶片处理段工艺参数松散回潮累计加水量、叶片加料累计加水量、叶片处理段加水总量及贮叶时间与切丝含水率的相关性进行了分析,描述了叶片处理工艺参数与切丝含水率的相关性,建立叶片处理工艺参数与切丝含水率均值的一元线性方程。结果表明,松散回潮累计加水量及叶片处理段累计加水量与切丝含水率均值相关性较强,一元线性回归方程较为显著;叶片加料加水累计量及贮叶时间与切丝含水率均值不具有相关性;贮叶时间对烟片加料含水率与切丝含水率的差值相关性较强,一元线性回归方程较为显著;叶片加料出口含水率与切丝含水率相关性较强。 相似文献
12.
以遗传性非胰岛素依赖型糖尿病ＫＫ小鼠为动物模型,研究钒对雌雄性糖尿病小鼠的降糖作用．实验选择３周龄的ＫＫ小鼠,雌雄各半,通过自由饮水方式给予雌雄性小鼠０ｍｇ/Ｌ、０.１ｍｇ/Ｌ和１００ｍｇ/Ｌ的钒酸铵,实验周期为１７周,观察不同剂量钒酸铵对血糖、甘油三酯和总胆固醇代谢的影响．研究结果表明,０１ｍｇ?Ｌ钒酸铵对雌雄性小鼠的血糖水平和血液生化指标没有明显的影响,高剂量钒酸铵（１００ｍｇ?Ｌ）明显降低雄性糖尿病小鼠的饮水量、血糖水平、糖基化血红蛋白、甘油三酯和总胆固醇等,葡萄糖耐量水平得到显著改善,对糖尿病小鼠的肝肾功能没有影响．结果提示钒酸铵对雌性小鼠和雄性小鼠具有降血糖作用,其作用效果有明显的性别差异． 相似文献
13.
It is very difficult, if not impossible, to remove the last traces of hypo from photographic papers by any known procedure of washing. The sulfur in the residual hypo ultimately, and especially under abnormal conditions of temperature and humidity, combines with the silver image to form yellowish brown silver sulfide. This phenomenon is known as sulfiding or “fading” of the image. The various factors which affect the rate of fading of images and the washing out of hypo from films and papers are outlined.Chemical methods of hypo elimination have been proposed from time to time but the majority of these have not been satisfactory because they tend to leave substances such as thionates in the photographic material, which are equally as difficult to wash out as hypo and which also tend to sulfide or fade the silver image. A new hypo eliminator is recommended consisting of two volatile chemicals, hydrogen peroxide and ammonia. This eliminator oxidizes the hypo to sodium sulfate, which is inert and soluble in water, while any excess eliminator evaporates on drying.Two formulas and treatments are proposed: (1) Complete elimination of hypo for use by the professional, advanced amateur, and photofinisher who demand the highest standard of photographic quality in their prints.(2) Almost complete elimination of hypo (less than o.oi milligram per square inch).Since the conditions to which prints will be subjected are rarely known in advance, use of the “complete elimination treatment” is advised in all cases. 相似文献
14.
气候变化对蒙古栎生长和气候生产力的影响 总被引：5，自引：0，他引：5
本文通过试验研究和模式计算,讨论了气候变化对蒙古栎(Quercus mongolica)的影响.结果表明,CO2浓度升高有利于蒙古栎的生长和材积量的累积,当CO2浓度增加1倍时,叶面积增加28.1%,主茎新增量增加23.3%,分株数增加22.5%,叶片气孔阻力增加41.8%,而光合作用速率增加16.5%;而土壤干旱不利于蒙古栎的生长和材积的累积,当土壤湿度由60%～80%下降到45%～60%时,叶面积减小36.5%,主茎新增量减少34.3%,分株数减少37.5%,光合作用速率减小35.1%.大气中CO2浓度升高可以减弱干旱所带来的不利影响.我国东北地区蒙古栎的气候生产力在118 m3～288m3/hm2之间,积温对蒙古栎数量成熟龄时材积量的影响不大,但积温增加可以缩短蒙古栎的成熟龄,从而缩短蒙古栎的生长周期,而降水和辐射增加有利于蒙古栎气候生产力的提高. 相似文献
15.
P. Subash 《Indian journal of clinical biochemistry : IJCB》2016,31(2):185-193
The objective of the present study was to investigate the antioxidant status and the extent of oxidative DNA damage in lymphocytes and their relation with essential hypertension (EHT). A total of 100 South Indian subjects aged 30–65 were included for the study. Of these 50 were normotensive controls (group-1) with blood pressure ≥120/80 mm Hg, 50 were newly diagnosed (group-2) and were not on any antihypertensive drugs, but had systolic blood pressure ranging between 140 and 160 mmHg and diastolic blood pressure 95–100 mmHg and 50 newly diagnosed essential hypertensive patients underwent drug therapy for 1 year was considered as group-3. Enzymatic and non-enzymatic antioxidants significantly decreased and lymphocyte DNA damage was significantly increased in newly diagnosed hypertensive patients compared with control group. The major decrease in DNA damage and significant improvement in enzymatic and non-enzymatic antioxidants were observed after 1 year of antihypertensive therapy in treated group compared with newly diagnosed hypertensive patients. Total antioxidant status and lymphocyte DNA damage showed a strong negative correlation in all the three groups. Essential hypertension associated with oxidative stress which in turn causes genotoxic susceptibility to variety of disease including cancer. In the absence of DNA repair process and DNA checkpoint mechanisms, the genomic integrity is susceptible to extensive damage. In our study, increased oxidative DNA damage and decreased antioxidant levels were frequently observed in the newly diagnosed essential hypertensive patients, suggesting that oxidative stress is important in the pathogenesis of EHT. Therefore, the present study has additional clinical implication. Further investigations with large number of patients along with antioxidant supplement are highly warranted. 相似文献
16.
17.
Santosh Kumar Singh Achyut Narayan Kesari Prashant Kumar Rai Geeta Watal 《Indian journal of clinical biochemistry : IJCB》2007,22(2):48-52
The present study reveals the effect of Musa paradisiaca stem juice on blood glucose level (BGL) of normal & diabetic rats.
The dose of 500 mg/kg bodyweight produces a significant rise of 28.3% in blood glucose level after 6h of oral administration
in normal rats. Whereas, in sub diabetic rats the same dose produces a rise of 16.4% in blood glucose levels within 1h during
glucose tolerance test (GTT) and a rise of 16% after 4 h in fasting blood glucose levels of severe diabetic cases. These results
were unexpected and important to report as other species of Musa like Musa sapientum has been reported for its hypoglycemic
effect. 相似文献
18.
Gora Dadheech Sandhya Mishra Shiv Gautam Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2006,21(2):34-38
A disturbance in the antioxidant defense system including α-tocopherol, ascorbic acid and reduced glutahtione metabolism due
to free radical induced oxidative injury has been implicated in various neuro-psychiatric disorders. The roles of these antioxidants,
changes in their blood levels and correlation with oxidative stress were studied in a common psychiatric illness Schizophrenia.
Fifty-eight subjects of either sex ranging in age from 18–60 years divided into two age groups (≤40 and >40 years) diagnosed
for schizophrenia, and forty age and sex-matched normal subjects as controls were included in the study. Blood samples were
analyzed for malondialdehyde (MDA), α-tocopherol, total ascorbic acid (TAA), dehydro ascorbic acid (DHAA), reduced ascorbic
acid (RAA), leucocyte ascorbic acid (LAA) and reduced glutathione (GSH). A decrease in the levels of α-tocopherol, total ascorbic
acid and reduced glutathione was found in schizophrenics compared to normal controls. Further a significant rise in oxidative
stress and decreased antioxidant status was observed in the chronic stage of schizophrenia as compared to those in acute condition.
A significant rise in dehydroascorbic acid with concomitant fall in reduced ascorbic acid suggests scavenging action of ascorbic
acid and its utilization with increased oxidative stress as indicated by high blood malondialdehyde levels. Leucocyte ascorbic
acid, a better index of ascorbic acid status was also found to be reduced in schizophrenics, suggesting depletion of body
stores of ascorbic acid and the condition worsened with advancing age. 相似文献
19.
The decreased serum levels of triiodothyroinine (T3) and thyroxine (T4) in hypothyroid patients is well established but whether
there is any correlation of creatinephosphokinase (CPK) with hypothyroidism is not well established. There is a paucity of
reference on this study. Therefore a study of serum CPK and thyroid profile was carried out in thyroid diseases. In hypothyroid
patients T3, T4 levels in serum were found to be lowered with an increase level of thyroid stimulating hormone (TSH) associated
with marked rise in serum CPK level. In hyperthyroid patients serum levels of T3, T4 were found to be increased with decrease
in TSh with significant decrease in creatine phosphokinase level. Serum creatine phosphokinase levels thus show an inverse
relation with serum T3, T4 levels. 相似文献
20.
模拟根系分区交替滴灌对茄子生长与水分利用的影响研究 总被引：5，自引：0，他引：5
通过玻璃土箱试验模拟了交替滴灌方式、固定滴灌方式和常规滴灌方式对茄子生长、根系分布和产量及水分利用的影响。结果表明,交替滴灌使灌溉用水效率明显增加,产量水平上的水分利用效率达58．0kg/m^3,可节约用水30％以上并增加产量;交替滴灌减少水分入渗深度,刺激根系生长,明显提高根密度．并在土壤中分布均匀：交替滴灌通过部分根区干燥产生根源信号调节气孔行为,使蒸腾速率明显降低,而植株光合作用没有受到明显影响,使单叶水分利用效率得以提高。 相似文献